Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT07158463Recruiting
Plasma exchange in children with kidney disease
This study looks back at kids aged 1–18 who had a treatment called therapeutic plasma exchange (TPE) in the pediatric kidney unit. TPE is a procedure that replaces the liquid part of the blood, which may help with certain kidney conditions.
SohagAges 1–18 - NCT07153861Recruiting
Mouth tissue vs lip tissue for female urethral repair
This trial compares using a graft from the mouth or lip to treat a narrowed urethra in women. It aims to find which approach works better for improving urinary flow.
Tanta, El-GharbiaAges 18 years+ - NCT07096453RecruitingPhase 1/Phase 2
CMV prevention in kidney transplant patients switching to belatacept
This trial tests whether an experimental drug (CMVIG) can prevent CMV infection in kidney transplant patients who are switching to or already on belatacept, a newer immunosuppressant. It may help protect those at higher risk for CMV.
Minneapolis, MinnesotaAges 18–70 - NCT07159165Enrolling by invitation
Registry study of MIUS for enlarged prostate
This study collects information from men treated with a minimally invasive surgery called MIUS for an enlarged prostate that blocks urine flow. It aims to learn how well the procedure works by tracking results over time.
SamsunAges Any age - NCT07747740RecruitingPhase 2
Bladder cancer treatment after BCG therapy fails
This trial compares two combinations of chemotherapy drugs given directly into the bladder to see which works better for patients whose bladder cancer has not responded to BCG therapy.
Moscow, MoscowAges 18 years+ - NCT05176483RecruitingPhase 1
New drug combinations for advanced solid tumors
This trial tests a new drug called zanzalintinib, which may slow or shrink various types of advanced cancer. It is given together with other cancer treatments, and the study is looking at many different cancers including kidney, prostate, bladder, lung, liver, and more.
Phoenix, ArizonaAges 18 years+ - NCT07746895RecruitingPhase 4
Study of pegcetacoplan for C3G or IC-MPGN kidney disease
This study looks at how well pegcetacoplan works and how safe it is for people with two rare kidney diseases, called C3G and IC-MPGN. It will help doctors understand how the medicine helps patients in real life, outside of a strict clinical trial.
KingswoodAges Any age - NCT07747272Recruiting
Nerve-sparing prostate surgery and erectile function
This study looks at how your health before surgery affects your erectile function after robot-assisted prostate removal. It aims to help doctors predict and improve recovery of erectile function.
Florence, ItalyAges 18–75 - NCT07747727Recruiting
Ultrasound and walking tests for stress incontinence
This study looks at how the pelvic floor changes after menopause and whether simple tests like ultrasound and checking how you walk can help understand stress incontinence. It may help find better ways to diagnose this condition.
Banhā, QalyoubiaAges 50–65 - NCT06465069RecruitingPhase 1
Study of a new drug for advanced bladder and other solid tumors
This study tests a new drug (LY4052031) for people with several types of advanced solid tumors, especially bladder cancer. It aims to see if the drug is safe and effective when given alone or after other treatments have stopped working.
Duarte, CaliforniaAges 18 years+ - NCT06661720RecruitingPhase 3
Tivozanib and pembrolizumab after kidney cancer surgery
This trial is testing if adding the targeted therapy tivozanib to the immunotherapy drug pembrolizumab (Keytruda) can help prevent kidney cancer from coming back after all known tumors have been removed by surgery.
Phoenix, ArizonaAges 18 years+ - NCT06506643RecruitingPhase 1/Phase 2
Study of KLS-1 for solid tumors and CLL
This trial tests a new drug called KLS-1 for people with solid tumors (like melanoma, pancreatic, or prostate cancer) or chronic lymphocytic leukemia (CLL) that is no longer responding to standard treatments. The goal is to see if KLS-1 is safe and can shrink tumors or slow the cancer.
KropyvnytskyiAges 18 years+ - NCT07226544RecruitingPhase 2
Ivonescimab before surgery for high-risk kidney cancer
This trial tests giving the drug ivonescimab before surgery for patients with high-risk clear cell kidney cancer. The goal is to see if it can help shrink the tumor and improve outcomes.
Duarte, CaliforniaAges 18 years+ - NCT05334069Recruiting
Blood test study for early cancer detection in patients
This study collects blood from people with cancer and people without cancer (or with possible cancer) to test whether new blood tests can detect cancer earlier. Your blood samples help researchers evaluate how well these tests work.
Anchorage, AlaskaAges 40–75 - NCT07200830RecruitingPhase 3
Testing different schedules of a targeted radiation drug for advanced prostate cancer
This trial tests two different dosing schedules of a drug called Lutetium-177 PSMA RLT, which delivers radiation directly to prostate cancer cells. It is for men with advanced prostate cancer that has stopped responding to hormone therapy and has spread, who have not yet had chemotherapy for this stage of the disease.
Anchorage, AlaskaAges 18 years+ - NCT07277413RecruitingPhase 1
Study of IDE892 for advanced solid tumors with MTAP deletion
This study tests a new drug called IDE892, alone or in combination, for people with advanced solid tumors that have a specific genetic change (MTAP deletion). The goal is to see if the drug is safe and whether it can shrink tumors.
Santa Rosa, CaliforniaAges 18 years+ - NCT07223736Recruiting
AI education for new mothers after birth
This study tests an AI-based education tool for first-time mothers to help with recovery and reduce loneliness after childbirth. You participate from home using your smartphone for 2-6 weeks after delivery.
La Jolla, CaliforniaAges 18 years+ - NCT06439862Recruiting
Quality of life in children with posterior urethral valves
This study looks at how children with posterior urethral valves (a condition that affects urination) feel about their quality of life as they grow up. It will help doctors understand how these children are doing emotionally and socially, so they can improve care.
Bron, BronAges 6–17 - NCT05039619RecruitingPhase 2
Obinutuzumab trial for adolescents with active lupus kidney inflammation
This Phase 2 study tests obinutuzumab, a targeted antibody medicine, in teens with active lupus nephritis (inflammation in the kidney). It looks at whether it helps kidney disease and is safe, including how the body handles the drug.
Loma Linda, CaliforniaAges 5–17 - NCT05796375RecruitingPhase 2
Urine testing instead of repeat bladder scope checks
This Phase 2 study tests whether urine tests can help monitor “non-muscle-invasive” bladder cancer without doing as many invasive bladder scopes (cystoscopies). If you qualify, you may be able to replace some scope visits with urine sample testing while still keeping close watch for cancer coming back.
West Haven, ConnecticutAges 18 years+ - NCT07614477RecruitingPhase 2
Testing EVER001 for kidney protein-loss diseases
This study tests a new drug called EVER001 to see if it can reduce protein loss in urine and improve kidney function in patients with specific kidney diseases (FSGS, MCD, or IgAN). These are autoimmune kidney conditions that cause the kidneys to leak protein into the urine.
Beijing, Beijing MunicipalityAges 18–75 - NCT06931340RecruitingPhase 3
Adding chemo to hormone therapy for advanced prostate cancer
This trial is for men with metastatic prostate cancer that has already spread beyond the pelvis. It tests whether adding a chemotherapy drug (docetaxel) to the usual hormone therapy plus apalutamide can help control the cancer better than hormone therapy alone.
Tucson, ArizonaAges 18 years+ - NCT07594106RecruitingPhase 1/Phase 2
New immunotherapy for advanced prostate or kidney cancer
This trial tests new experimental drugs (REGN15505 and REGN4336) designed to target and attack cancer cells in advanced prostate cancer or kidney cancer. These drugs work by boosting your immune system to recognize and destroy cancer, and may be combined with other approved immunotherapy drugs.
Goodyear, ArizonaAges 18 years+ - NCT06632977RecruitingPhase 2
Matching targeted treatments to your prostate cancer's genetics
This trial is testing whether matching your cancer's specific genetic changes to a targeted treatment can help control metastatic prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. You may receive a drug, a radioactive treatment, or a combination based on your tumor's molecular profile.
Birmingham, AlabamaAges 18 years+
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.