Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,504 recruiting studies in this area right now.
By phase
- Not applicable2,821
- Phase 2564
- Phase 1366
- Phase 3271
- Phase 1/Phase 2230
- Phase 4194
- Phase 2/Phase 358
Top conditions
- Prostate Cancer651
- Bladder Cancer191
- Acute Kidney Injury136
- Chronic Kidney Diseases131
- Breast Cancer104
- Chronic Kidney Disease104
- Renal Cell Carcinoma80
- Urinary Incontinence64
- Colorectal Cancer60
- Kidney Cancer60
- Ovarian Cancer60
- Lung Cancer55
- Lupus Nephritis54
- Cancer51
- Melanoma50
- Benign Prostatic Hyperplasia48
- Prostate Cancer (Adenocarcinoma)46
- Renal Cancer46
Leading sponsors
- Mayo Clinic62
- National Cancer Institute (NCI)45
- Peking University First Hospital38
- M.D. Anderson Cancer Center36
- Novartis Pharmaceuticals35
- Chinese University of Hong Kong34
- AstraZeneca30
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris28
- University of California, San Francisco28
Where studies are running
- California350
- Alabama112
- Arizona103
- Florida97
- New York95
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Ohio48
Recruiting studies4,504 total
- NCT07648290RecruitingEarly Phase 1
Testing a Self-Check System After Bladder Botox Treatment
This study tests a computer-based system to help you monitor your bladder symptoms after receiving Botox injections for overactive bladder or urge incontinence. The goal is to see if you can use this self-check tool at home to track how well the treatment is working.
Cleveland, OhioAges 18 years+ - NCT07741214Enrolling by invitation
Low-power prostate surgery comparison
This trial compares two common surgical methods for men with bothersome urinary symptoms due to an enlarged prostate. It aims to find which approach gives better relief with fewer side effects.
CairoAges 50 years+ - NCT07739121Recruiting
Testing AI vs. tumor boards for cancer treatment advice
This trial compares treatment recommendations from large language models (AI) against those from experienced tumor boards for five common cancer types. The goal is to see if AI can help doctors make better decisions.
ParisAges 18 years+ - NCT07740239Recruiting
Study on frailty in seriously ill adults
This study looks at why some seriously ill adults become frail. It involves imaging and other tests to help doctors better understand and care for patients with serious conditions.
TampereAges Any age - NCT04812366RecruitingPhase 2
Genetic test-guided treatment before prostate surgery
This trial tests different drugs before prostate surgery based on a person's genetic profile. It aims to find better treatments for high-risk prostate cancer that hasn't spread yet.
Sacramento, CaliforniaAges 18 years+ - NCT06995677RecruitingPhase 2
TYRA-300 pill for low-grade bladder cancer with FGFR3 change
This study tests an experimental pill called TYRA-300 for people with low-grade bladder cancer that hasn't spread into the muscle layer. The pill targets a specific gene change (FGFR3) found in the tumor. The goal is to see if it can slow or shrink the cancer.
Homewood, AlabamaAges 18 years+ - NCT06613100RecruitingPhase 1
Xaluritamig before prostate surgery for high-risk prostate cancer
This study tests an experimental drug called xaluritamig given before surgery for men with localized prostate cancer that is intermediate or high risk. The goal is to see if it can help shrink the cancer before the prostate is removed.
San Francisco, CaliforniaAges 18 years+ - NCT07688447Recruiting
Comparing two surgeries for small enlarged prostate
This study compares two surgical methods for men with a small enlarged prostate (30 mL or less) who have moderate to severe urinary symptoms. It tests whether adding a small cut in the bladder neck to the standard laser surgery (ThuLEP) works better than ThuLEP alone.
Shanghai, Shanghai MunicipalityAges 50–85 - NCT07483827RecruitingPhase 1
Testing CPV-104 safety in healthy people and C3G patients
This trial tests a new drug called CPV-104. First, healthy volunteers will receive a single dose to check safety. Then, people with C3 glomerulopathy (a rare kidney disease) will receive multiple doses to see if it helps and is safe.
ViennaAges 18 years+ - NCT07239219Recruiting
Testing a special rinse to prevent infection after catheter removal
This trial tests whether using a special antiseptic solution (Irrisept) when removing a urinary catheter can lower the chance of getting a urinary tract infection. It is for people visiting a urology clinic for catheter removal who are not already on antibiotics.
Columbus, OhioAges 18 years+ - NCT07525960RecruitingPhase 1
Testing NDI-5001 for X-linked Nephrogenic Diabetes Insipidus
This study tests a new drug called NDI-5001 in adult men with a specific genetic form of nephrogenic diabetes insipidus (a condition where the kidneys cannot concentrate urine properly). The trial checks whether the drug is safe, how your body handles it, and whether it might help reduce excessive urination and thirst.
Jacksonville, FloridaAges 18–55 - NCT06910813RecruitingPhase 1/Phase 2
Gene therapy trial for children with cystinosis
This trial tests a new gene therapy called DFT383 for children aged 2 to 5 with nephropathic cystinosis. It aims to see if the treatment is safe and can help improve kidney function.
Phoenix, ArizonaAges 2–5 - NCT07646847Recruiting
A support program for people with cancer on immunotherapy
This study tests a program that helps people with cancer manage side effects and find resources for needs like food, transportation, or housing. It is for patients who are starting or recently started immunotherapy for certain cancers.
Basking Ridge, New JerseyAges 18 years+ - NCT07419841RecruitingPhase 1
A study of CTX-10726 for certain advanced cancers
This trial tests a new drug called CTX-10726 in people with advanced kidney, liver, stomach, or uterine cancer that has not responded to standard treatments. The goal is to see if the drug is safe and tolerable.
Omaha, NebraskaAges 18 years+ - NCT05759923RecruitingPhase 1
Study of OATD-02 for hard-to-treat solid tumors
This early (first-in-human) study tests whether OATD-02 is safe and tolerable, and whether it shows any anti-cancer activity. It is for adults with certain advanced or metastatic cancers that have already been treated with the standard options.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT07085104RecruitingPhase 1
Study of ALLO-329 for lupus, myositis, or scleroderma
This trial tests a new one-time cell therapy (ALLO-329) made from donor cells to target and calm overactive immune cells in people with lupus, myositis, or scleroderma that hasn't improved with usual medications. It aims to see if this treatment is safe and can help reduce disease activity.
Phoenix, ArizonaAges 18–74 - NCT07011719RecruitingPhase 3
Kidney cancer trial: new combo vs. cabozantinib alone
This trial tests a new drug (casdatifan) combined with cabozantinib for advanced clear cell kidney cancer, comparing it to cabozantinib alone. It's for people who haven't taken these specific medicines before and are still in fairly good health.
Gilbert, ArizonaAges 18 years+ - NCT05751434RecruitingPhase 2
Exercise therapy for prostate cancer patients on active surveillance
This trial tests whether an exercise program can help men with early-stage prostate cancer who are being monitored instead of treated. If you are not very active now, you may be able to join a structured exercise plan to see if it improves your health and cancer signs.
Durate, CaliforniaAges 18 years+ - NCT06963346RecruitingPhase 1
Bladder cancer trial: targeted drug plus immunotherapy before surgery
This trial tests a combination of a targeted drug (HDAC inhibitor, given directly into the bladder) and an immunotherapy (Durvalumab, given through a vein) before bladder removal surgery. It's for people with muscle-invasive bladder cancer who cannot take the chemo drug cisplatin.
Tampa, FloridaAges 18 years+ - NCT07224776RecruitingPhase 1
Sparsentan for proteinuria from VEGF inhibitor cancer treatment
This trial tests if sparsentan can reduce high levels of protein in the urine caused by VEGF signaling pathway inhibitors (VSPIs), a type of cancer treatment. It may help protect kidney function during cancer therapy.
Boston, MassachusettsAges 18 years+ - NCT06604130Enrolling by invitation
Prostate cancer diagnosis using blood exosomes
This study explores whether a simple blood test that looks at tiny particles called exosomes can help diagnose prostate cancer, possibly reducing the need for biopsies. If you have higher PSA levels and are scheduled for a biopsy, this trial might be a fit.
Lanzhou, GansuAges 18 years+ - NCT06948552RecruitingPhase 2
Using a light-sensitizing drug to find cancer in the upper urinary tract
This trial tests whether taking a drug called 5-ALA before a scope procedure helps doctors spot cancer cells in the upper urinary tract more clearly. If you are having a scope to check for or treat a tumor in this area, this experimental imaging method might help guide treatment.
Detroit, MichiganAges 18–75 - NCT05267626RecruitingPhase 1/Phase 2
AU-007 antibody for hard-to-remove or spread skin and lung cancers
This trial tests AU-007, an antibody that targets the IL-2 pathway, in people with certain advanced skin (melanoma) or lung (NSCLC) cancers. It’s designed for cancers that have already progressed after prior immune and other treatments, to see if AU-007 can shrink tumors or control disease.
Miami, FloridaAges 18 years+ - NCT01500447Recruiting
Study of inherited causes of low puberty hormones
This study looks at families to understand inherited (genetic or family-related) reasons some people have delayed puberty or develop puberty abnormally. It may help doctors better figure out the cause of low sex hormone levels and related hormone problems.
Bethesda, MarylandAges 1 month–120 years
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,504 recruiting nephrology & urology studies from the U.S. registry right now, out of 7,162 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.