Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT07246304RecruitingEarly Phase 1
Cell therapy for DLL3-positive small cell lung cancer
This trial tests a new cell therapy called TC-D101 for people with a type of small cell lung cancer that has DLL3 protein on its surface. It may be an option if standard treatments have stopped working or are not suitable.
Nanjing, JiangsuAges 18–75 - NCT07245368RecruitingPhase 1/Phase 2
Testing a new asthma drug in healthy people and those with asthma
This study tests an investigational drug called PRA-216, first in healthy volunteers to check safety, then in people with mild-to-moderate asthma to see if it helps control symptoms. It's an early-stage trial to find out if the drug is safe and works.
Botany, New South WalesAges 18–65 - NCT04025541Recruiting
Blood tests to study tumor markers
This trial looks at blood samples to measure substances that may reflect cancer (tumor markers). It may help doctors understand cancer better and improve future monitoring, as long as you can safely and regularly take part.
MontpellierAges 18 years+ - NCT04903262Recruiting
Extra CO2 removal to protect lungs in moderate ARDS
This study tests an “extra-CO2 removal” breathing support approach to help protect the lungs in people with moderate ARDS, a serious lung injury. You would be on a ventilator for a short time, and the team would check whether this approach improves breathing outcomes while aiming to be safer for the lungs.
BolognaAges 18–100 - NCT07243249Recruiting
Quick virus test to guide antibiotic use
This study tests whether a quick test for COVID-19, flu, and RSV can help doctors avoid giving antibiotics when they aren't needed. It's for people with fever or chest infection symptoms who are not sick enough to be hospitalized.
GarchesAges 1 year+ - NCT07240558RecruitingPhase 3
Flu vaccine study for organ transplant patients
This study tests whether a special flu vaccine, designed for a future pandemic, works safely in people who have had an organ transplant. It aims to find a better way to protect transplant patients from severe flu.
Toronto, OntarioAges 18 years+ - NCT07247669Recruiting
AI phone triage for emergencies
This study tests if artificial intelligence can help identify time-sensitive emergencies like stroke, heart attack, or trouble breathing from recorded phone calls. The goal is to make emergency response faster and more accurate.
Málaga, MálagaAges Any age - NCT07243132Recruiting
Long-term survivors in metastatic lung cancer study
This study looks at people who have lived more than three years with advanced lung cancer (non-small cell or small cell) that has spread. The goal is to better understand why some people do well for a long time and how to help more patients.
Aix-en-ProvenceAges 18 years+ - NCT07248774Recruiting
Breathing exercises for children with pleural effusion
This trial compares three types of breathing exercises to help children with pleural effusion (fluid around the lungs) recover after a chest tube is placed. The exercises aim to improve lung function and make breathing easier.
Lahore, Punjab ProvinceAges 5–16 - NCT07245329Recruiting
Expanded sinus surgery with throat tissue ablation for nasal polyps
This trial tests a more thorough sinus surgery combined with removing lymphoid tissue in the throat to see if it helps people with nasal polyps. Researchers want to know if this approach reduces inflammation and improves symptoms.
Wuhan, HubeiAges 18–65 - NCT07249567Recruiting
Comparing COPD, PRISm, and healthy adults
This study compares the health of people with COPD (chronic lung disease) and those with PRISm (a milder lung condition) to healthy adults. The goal is to understand how these conditions affect daily life and overall health.
KarabükAges 40 years+ - NCT07246265Recruiting
Morphine clearance study for sickle cell crisis in ICU
This study looks at how the body clears morphine in adults with sickle cell disease who are in the intensive care unit (ICU) for a pain crisis or acute chest syndrome and are receiving morphine through a patient-controlled analgesia (PCA) pump. The goal is to understand how kidney function affects morphine breakdown.
Tours, FranceAges 18 years+ - NCT07241182Recruiting
Mushroom extract supplement for lung cancer chemo patients
This study tests whether a supplement from a medicinal mushroom (Antrodia cinnamomea, also known as niu zhang zhi) can improve quality of life for people with lung cancer who are receiving platinum-based chemotherapy.
TaipeiAges 18–99 - NCT07247461Recruiting
Draining lung abscesses through the chest wall
This trial tests if draining a lung abscess through a tube placed in the chest is effective. If you have a lung abscess at least 4 cm wide in the outer part of your lung and signs of infection, you may be able to join.
AarhusAges 18 years+ - NCT07247474Recruiting
Using electrical impedance tomography for heart and lung imaging
This trial uses a safe, non-invasive technique called EIT to monitor heart and lung function in children and young adults with certain heart or lung conditions, compared with healthy volunteers. It may help doctors better understand and manage these conditions.
Aurora, ColoradoAges 2 weeks–25 years - NCT07241208Recruiting
Comparing two ways to place breathing tube for lung surgery
This study compares two methods to insert a special breathing tube (double-lumen tube) for lung surgery. One method uses a camera on a flexible scope (fiberoptic bronchoscopy) and the other uses a video laryngoscope. Your participation could help doctors know which method works better.
SeoulAges 19 years+ - NCT07248995Recruiting
Ultrasound to set breathing support in brain injury patients with lung issues
This trial tests if chest and head ultrasound can help doctors adjust the breathing machine (PEEP) for patients with both a severe brain injury and a serious lung condition called ARDS. The goal is to improve care without harming the brain.
ThessalonikiAges 18 years+ - NCT07247227Recruiting
Sugemalimab plus chemotherapy for advanced lung cancer
This trial tests a new immunotherapy drug (sugemalimab) combined with chemotherapy as a first treatment for advanced non-small cell lung cancer. It aims to see if this combination works well in real-world patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07242547RecruitingPhase 2
Tarlatamab maintenance for limited-stage small cell lung cancer
This trial tests a new immunotherapy medicine called tarlatamab given as maintenance therapy after initial treatment for limited-stage small cell lung cancer. It aims to keep the cancer from coming back.
Albacete, AlbaceteAges 18 years+ - NCT07243964Recruiting
Predicting lung transplant outcomes with molecular analysis
This study uses advanced blood and tissue testing to predict how well a new lung will work after transplant. If you've had a lung transplant and are stable, you may help researchers improve care for future patients.
ShanghaiAges 18 years+ - NCT07245888Recruiting
Studying pneumonia in ventilated ICU patients
This study looks at different types of lung infections in ICU patients on breathing machines. By analyzing fluid from your lungs, researchers hope to better understand pneumonia and improve treatment.
LimogesAges 18 years+ - NCT07243652Recruiting
Helping kids recover after bronchiolitis
This study tests a program called I-DECIDE to help children recover after being hospitalized with bronchiolitis. It may help parents manage symptoms and decide when to seek care.
Birmingham, AlabamaAges birth–2 years - NCT07249372RecruitingPhase 2
DRP-104 for a specific type of advanced lung cancer
This trial tests a new drug, DRP-104, for people with advanced non-small cell lung cancer that has a change in the NFE2L2 or KEAP1 genes. It is for people whose cancer has gotten worse after standard treatments like chemotherapy and immunotherapy.
New York, New YorkAges 18 years+ - NCT07243873Recruiting
Improving lung cancer diagnosis with synthetic PET scans
This study uses a computer-generated PET scan from your CT scan to help doctors diagnose and plan treatment for non-small cell lung cancer more precisely. It is observational, meaning no new treatments are given—just extra imaging analysis.
Zunyi, GuizhouAges 18–85
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.