Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,626 recruiting studies in this area right now.
By phase
- Not applicable4,298
- Phase 2850
- Phase 1470
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Ovarian Cancer72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Colorado71
Recruiting studies6,626 total
- NCT05382572Recruiting
Pulmonary fibrosis community registry for patients and families
This study builds a community registry to learn about people affected by pulmonary fibrosis and related lung conditions, including patients, caregivers, and close family. By joining, you help researchers better understand needs and experiences in the real world.
Chicago, IllinoisAges 18 years+ - NCT05384873Recruiting
Immunonutrition to improve immunotherapy in metastatic lung cancer
This trial studies whether adding special nutrition (oral immunonutrition supplements) can help immunotherapy work better in people with metastatic non-small cell lung cancer. Participants receive immunotherapy, with or without chemotherapy, and must be able to take oral supplements.
PaviaAges 18 years+ - NCT05384769Recruiting
Blood test for early lung cancer screening in high-risk people
This study checks whether a blood test (a liquid biopsy) can be used along with standard lung cancer screening to find lung cancer early in people at higher risk. It may help see if the blood test is practical and useful for screening—without needing symptoms.
Duarte, CaliforniaAges 50–80 - NCT05387304Recruiting
Follow-up study for people with COVID infection in Shanghai
This study follows people in Shanghai who have tested positive for the COVID virus, even if they have no symptoms yet. It helps doctors understand what happens after infection and in people who later get a diagnosis.
ShanghaiAges Any age - NCT05387369Recruiting
Real-world study of Paxlovid for hospitalized COVID-19 patients
This study checks how Paxlovid works in everyday care for people who are hospitalized with confirmed COVID-19. If you have a positive COVID-19 test and mild to moderate symptoms, this trial may help doctors understand how well the treatment performs outside of tightly controlled settings.
ShanghaiAges 12 years+ - NCT05389774Recruiting
Testing an AI tool that predicts lung cancer risk from CT scans
This study tests whether Optellum’s AI prediction tool can better identify which lung nodules found on CT scans are more likely to be cancer. You may be asked to provide specific types of CT images so the tool can be evaluated.
BangorAges 35 years+ - NCT05391100Recruiting
Screening people with rheumatoid arthritis for lung scarring
This study looks for early lung scarring in people who have rheumatoid arthritis. It may help find a serious lung condition earlier so doctors can watch or treat it sooner.
BudapestAges 40 years+ - NCT05391737Recruiting
Study of fluid in the lungs after open-water swimming
This study looks at what happens in the lungs after open-water swimming. It may help doctors better understand and recognize “swimming-induced lung fluid,” especially by using lung ultrasound when symptoms happen.
FalunAges 18 years+ - NCT05392881Recruiting
Lung disease biobank for adults followed at a university clinic
This study collects and stores samples and health information from adults being followed for interstitial lung disease or certain rare lung conditions. The goal is to help researchers study these diseases over time and improve future care.
Kansas City, KansasAges 18 years+ - NCT05395689RecruitingPhase 3
Dust mite allergy vaccine for ongoing runny nose and asthma
This Phase 3 study tests Beltavac®, a treatment aimed at dust mite allergies, to see if it can improve persistent nasal allergy symptoms and help people whose asthma is also affected. You may be a good match if you have confirmed dust mite sensitization and ongoing moderate-to-severe symptoms.
Orihuela, AlicanteAges 12–65 - NCT05395598Recruiting
Long-term follow-up for large aortic root aneurysm risks
This study follows people with an enlarged aortic root to track how often serious complications happen over time. It may help doctors understand risk and improve care by observing outcomes for up to five years.
Lille, Please Choose...Ages 45–80 - NCT05397717Recruiting
Study of outcomes after spontaneous collapsed lung
This study follows adults with a “spontaneous pneumothorax,” meaning a lung collapse that happens without trauma, to see what outcomes they experience. You may be followed during and after hospitalization, because your results can help doctors understand and improve care.
Hong KongAges 18 years+ - NCT05398094RecruitingPhase 2
Sotorasib for KRAS-mutant Stage III lung cancer without chemo-radiation
This Phase 2 study tests sotorasib (also called AMG510) in people with Stage III lung cancer that cannot be removed by surgery and that has a specific KRAS mutation (p.G12C). You may be able to join if you cannot safely receive chemo-radiotherapy at the same time, and the study checks whether sotorasib can help shrink or control the cancer.
Alicante, AlicanteAges 18 years+ - NCT05399056Recruiting
Peer support and storytelling to help COPD lung rehab
This study aims to improve how well people with COPD can take part in pulmonary rehabilitation by using peer coaching and short storytelling videos. If you recently had a COPD flare and are being referred to lung rehab, this may offer extra support to help you complete the program.
Springfield, MassachusettsAges 40 years+ - NCT05401110RecruitingPhase 1
Osimertinib plus antibody treatment for EGFR-mutated lung cancer
This Phase 1 study tests the combination of osimertinib (a targeted lung cancer pill) with an antibody called carotuximab to treat advanced EGFR-mutated non-small cell lung cancer. It aims to see whether adding the antibody can help when the cancer has grown despite prior EGFR-targeted therapy.
Beverly Hills, CaliforniaAges 18 years+ - NCT05401071RecruitingPhase 2/Phase 3
Test shorter rifapentine-based treatment for drug-sensitive TB
This trial studies whether a rifapentine-based TB regimen can work just as well while shortening treatment time. It’s for people with rifampicin-sensitive, smear-positive lung tuberculosis.
Guiyang, GuizhouAges 18–60 - NCT05403177Recruiting
Share your cancer data and samples for Ontario research
This study collects and combines medical records, genetic (genomic) data, and tumor/blood samples from people with cancer. It helps researchers build and improve a large “gold standard” cancer dataset that can support future studies and better understanding of cancer.
Kingston, OntarioAges 18 years+ - NCT05406570Recruiting
Personalized breathing settings for adults with severe ARDS
This trial tests a more tailored way to set the amount of air delivered by a ventilator in people with severe ARDS. The goal is to see if personalized breathing settings can improve breathing and heart-related monitoring while patients are in intensive care.
LyonAges 18 years+ - NCT05407792Recruiting
Long-term tablets to help bronchiectasis flare-ups
This trial studies whether long-term Staphylococcus albicans tablets can safely reduce bronchiectasis flare-ups and improve symptoms. It may help people with frequent infections/attacks due to bronchiectasis.
Jinan, ShandongAges 18 years+ - NCT05415267RecruitingPhase 3
Boosting COVID protection during long-term immune suppression
This study looks at how well a COVID-19 booster works in adults who need long-term medicines that lower immune response. It aims to see whether immunosuppressed people benefit from booster vaccination safely.
Blacktown, New South WalesAges 18 years+ - NCT05417776RecruitingPhase 2
PET scan test for early lung scarring
This trial uses a special PET/MRI scan to look for early signs of lung scarring and inflammation using a “collagen-targeting” tracer. It may help doctors better identify early interstitial lung disease (IL D) and track it over time.
Boston, MassachusettsAges 40 years+ - NCT05419076RecruitingPhase 2
SRS radiation for small cell lung cancer with brain spread
This Phase 2 trial tests a type of focused radiation (stereotactic radiosurgery, or SRS) for people with small cell lung cancer that has spread to the brain. It looks at whether this approach can treat brain metastases when the cancer has limited to a certain number of spots.
Basking Ridge, New JerseyAges 18 years+ - NCT05425264Recruiting
Home exercise coaching by video after COVID
This trial tests a home-based exercise and physical therapy program delivered by video after a COVID-19 infection. It may help you rebuild strength and breathing safely, especially if you also have certain long-term health conditions.
Baltimore, MarylandAges 50–85 - NCT05426135Recruiting
AI tool to assess cancer risk and guide care
This study tests an artificial intelligence (AI) system that uses your health information and medical images to better judge cancer risk and support diagnosis and treatment decisions. It may help doctors make more consistent assessments by combining clinical records, imaging, and other lab-style data.
Wuhan, HubeiAges 18–75
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,626 recruiting pulmonology studies from the U.S. registry right now, out of 10,582 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.