Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06080503Recruiting
Comparing shorter vs. standard radiation for early vocal cord cancer
This study tests if a shorter course of radiation (hypofractionated) works as well as the standard longer course for people with early-stage cancer of the vocal cords. The goal is to find a treatment that is more convenient and has similar results.
Dallas, TexasAges 18 years+ - NCT06080776RecruitingPhase 3
SH-1028 vs placebo for early-stage EGFR-mutated lung cancer
This trial tests a pill called SH-1028 (an EGFR-targeted drug) versus a placebo to see if it helps prevent lung cancer from coming back after surgery in people with EGFR-mutated NSCLC. You may be eligible if you had complete removal of stage II-IIIB NSCLC and your tumor has a specific EGFR mutation.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06082492Recruiting
PET/CT scans for follow-up of stage III lung cancer
This trial is testing whether adding a PET/CT scan to routine follow-up care helps patients with stage III non-small cell lung cancer. It aims to see if this extra imaging can detect any return of cancer earlier, which may help with treatment decisions.
Hilversum, UtrechtAges 18 years+ - NCT06082401Recruiting
Adding filtering to improve donor lungs
This trial tests whether adding a special filtering treatment (hemodiafiltration) during the lung reconditioning process (EVLP) can help improve marginal donor lungs before transplant. It aims to see if more lungs can be used for patients waiting for a transplant.
ViennaAges Any age - NCT06084078Recruiting
Rural Illinois lung cancer screening study
This study aims to improve lung cancer screening for people in rural Illinois who have a history of heavy smoking. It tests a program to help more people get screened and catch cancer early.
Springfield, IllinoisAges 50–80 - NCT06084806RecruitingPhase 2
Testing reliability of a new PET scan for NSCLC on immunotherapy
This study tests a new PET imaging agent to see how consistently it shows immune activity in the body. It is for people with advanced non-small cell lung cancer who are about to start immunotherapy.
Iowa City, IowaAges 18 years+ - NCT06085209RecruitingPhase 1
Cold spray treatment for non-cancerous airway narrowing
This trial tests a freezing spray (cryospray) to treat narrowing of the windpipe (trachea) that is not caused by cancer. It may be an option if you need a procedure to open your airway.
Richmond, VirginiaAges 18 years+ - NCT06086366Recruiting
Brain scan study for depression after COVID-19
This study uses brain scans to understand depression that starts soon after COVID-19. Researchers want to see if there are changes in brain chemistry related to depression, and you may help find new treatment targets.
Toronto, OntarioAges 18–75 - NCT06087315Recruiting
Study of oxygen use in children's hospitals
This study looks at how hospitals in six countries use pulse oximeters and oxygen therapy to treat children. It aims to find ways to improve oxygen delivery and care for children with serious illnesses.
Phnom PenhAges birth–15 years - NCT06087692Recruiting
Video game therapy for lung disease patients
This trial tests whether playing interactive video games can help people with interstitial lung disease (a type of chronic lung condition). It aims to improve breathing and daily function through fun, guided exercises.
IstanbulAges 40–65 - NCT06089161Recruiting
Sleep Apnea Treatment and Alzheimer's Risk in Black Adults
This trial tests whether personalized sleep apnea treatment can help protect memory and thinking in Black older adults. If you have sleep apnea and are concerned about Alzheimer's, this study may help you and others like you.
Miami, FloridaAges 60–85 - NCT06089096Recruiting
Sleep apnea and memory in people with mild memory problems
This study looks at whether sleep apnea (pauses in breathing during sleep) is linked to thinking and memory in people who have mild memory problems. You will do a home sleep test and take memory tests to help researchers find this connection.
Hong KongAges 18 years+ - NCT06089603RecruitingPhase 4
CPAP for Sleep Apnea with High Red Blood Cells
This study tests whether CPAP therapy (a machine that helps keep your airway open while you sleep) can lower high red blood cell counts in people who have both sleep apnea and polycythemia. It may help reduce the need for other treatments.
Madrid, MadridAges 18–80 - NCT06090266RecruitingPhase 1/Phase 2
Study of OR502 alone and with other cancer treatments
This trial tests an experimental drug called OR502, which targets a protein on immune cells, to see if it can help fight advanced solid tumors. It is given alone or with other anti-cancer drugs, and the study aims to find the best dose and see how well it works.
Austin, TexasAges 18 years+ - NCT06092008Recruiting
New pneumonia tests for adults 65 and older
This study tests new ways to diagnose pneumonia faster and more accurately in older adults who come to the emergency room with breathing problems. The goal is to see if these new tests work better than the current methods.
Columbus, OhioAges 65 years+ - NCT06092554Recruiting
Probiotics to prevent pneumonia in ventilated patients
This trial tests whether giving probiotics to patients on a breathing machine (mechanical ventilation) can help prevent pneumonia. It is for adults who are on a ventilator after a recent head injury, stroke, or brain bleed.
BrusselsAges 18–80 - NCT06094010RecruitingPhase 3
Flu treatment and transmission study for children and families
This study tests how well a single-dose flu treatment (baloxavir marboxil) works for children with the flu and whether it stops the flu from spreading to family members. If your child has early flu symptoms and lives with others, participation could help protect your household.
Birmingham, AlabamaAges 3 weeks–11 years - NCT06093633Recruiting
Sleep study comparing new device to standard method
This study tests a new wearable device (WP) against standard sleep testing (PSG) for people with suspected sleep problems. It may help diagnose issues like sleep apnea more comfortably.
Baltimore, MarylandAges 12–99 - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT06095505RecruitingPhase 2
Alisertib for extensive stage small cell lung cancer
This trial tests a new drug called alisertib for people with small cell lung cancer that has spread. It is for those who have already tried standard treatments (chemotherapy and immunotherapy) and need another option.
Daphne, AlabamaAges 18 years+ - NCT06099795Recruiting
Breath test vs. swab test for COVID-19
This study checks if a new breath test (eBAM-CoV) can accurately detect COVID-19 compared to the usual nose/throat swab test (RT-PCR). If you have symptoms or were exposed and are getting tested anyway, you may be able to help by also providing a breath sample.
NîmesAges 18 years+ - NCT06102057RecruitingPhase 2
PET-guided small volume chemoradiation with immunotherapy for lung cancer
This trial tests a new combination of chemotherapy, radiation, and immunotherapy (durvalumab) for people with stage III non-small cell lung cancer that cannot be removed with surgery. The goal is to see if giving a smaller, more focused radiation dose can be just as effective with fewer side effects.
DresdenAges 18 years+ - NCT06102330Recruiting
Helping parents decide about home breathing machines
This study helps parents like you who are deciding whether their child should have a breathing machine at home. You'll use a website or get support by phone to learn about your options and share what matters most to your family, so doctors and families can make better choices together.
Tampa, FloridaAges 18 years+ - NCT06102499Recruiting
Comparing oxygen readings from different pulse oximeters in the ICU
This study tests how well different pulse oximeters measure oxygen levels compared to a direct blood test in patients in the intensive care unit. It aims to find which devices are most accurate for monitoring oxygen.
Montreal, QuebecAges birth–100 years
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.