Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06062212Recruiting
Effects of lung pressure on recovery in severe ARDS on ECMO
This trial looks at how changes in lung pressure during breathing might affect recovery in patients with severe ARDS who are on a heart-lung bypass machine (ECMO). It could help doctors improve treatment for people with this serious lung condition.
Beijing, Beijing MunicipalityAges 18–75 - NCT06065215Recruiting
Early-life MRI to Predict Breathing Problems in Extremely Preterm Infants
This study uses an MRI scan to look at how the lungs develop in babies born very early (before 29 weeks of pregnancy). The goal is to see if early MRI images can help predict future breathing problems, so doctors can better support these infants.
Ottawa, OntarioAges 8 months–1.8 years - NCT06066138RecruitingPhase 1
Trial: Adjusting Atezolizumab Dose Based on Drug Levels in Blood
This study tests whether adjusting the dose of the immunotherapy drug atezolizumab (Tecentriq) based on its levels in your blood works well. You may be able to join if you have advanced cancer and your doctor already plans to give you this drug (alone or with other approved treatments).
Bethesda, MarylandAges 18–120 - NCT06068049Recruiting
Study of osimertinib in patients with EGFR-mutated lung cancer in Spain
This study is looking back at how people with EGFR-mutated non-small cell lung cancer who have taken osimertinib (Tagrisso) actually did in everyday medical care in Spain. It includes patients who took osimertinib in several different treatment scenarios.
A CoruñaAges 18 years+ - NCT06068322Recruiting
Very intense interval training for people with COPD
This study tests whether a very intense, short burst of exercise (supramaximal high-intensity interval training) is safe and effective for people aged 60 and older with or without COPD. It aims to see if this type of exercise can improve fitness and daily life.
Hasselt, DiepenbeekAges 60 years+ - NCT06068335Recruiting
Understanding immunity in allergic asthma
This study looks at how the immune system works in people with allergies or asthma compared to healthy people. It may help find new ways to treat these conditions.
Orlando, FloridaAges 18 years+ - NCT06068647Recruiting
Ultrasound and breathing tests for lung disease patients
This study uses ultrasound and sensors to monitor lung health in people with certain lung conditions, including those that cause scarring or breathing problems. It aims to find better ways to track lung disease, which could help manage your condition more effectively.
RomeAges 18 years+ - NCT06069115Recruiting
How radiation affects lung function in breast cancer patients
This study looks at how radiation therapy for breast cancer may affect your lungs over time. Researchers will measure lung function and see if problems develop, so they can better understand and protect patients.
Novosibirsk, Novosibirsk OblastAges 18 years+ - NCT06069570RecruitingPhase 1
Gamma delta T cells and low dose radiation for advanced lung or bone cancer
This trial tests a new type of immune cell called gamma delta T cells combined with low-dose radiation to treat people with advanced lung cancer or solid tumors that have spread to the bone. It is only for patients who have already tried standard treatments and either didn't get better or couldn't tolerate them.
Tucson, ArizonaAges 18 years+ - NCT06070688Recruiting
A test to tell if your breathing infection is bacterial or viral
This study tests a new way to quickly figure out if a respiratory infection is caused by bacteria or a virus. Knowing this could help doctors choose the right treatment faster and avoid unnecessary antibiotics.
Houston, TexasAges 18 years+ - NCT06071013RecruitingPhase 1/Phase 2
Nintedanib plus EGFR inhibitor for EGFR-mutated lung cancer
This trial tests a combination of two drugs—nintedanib and an EGFR inhibitor—for people with EGFR-mutated non-small cell lung cancer whose cancer has stopped responding to their first EGFR inhibitor treatment. The goal is to see if adding nintedanib can help control the cancer again.
TaichungAges 20–70 - NCT06070870Recruiting
Lung screening help for Black adults
This trial helps Black or African-American adults who smoke or quit recently learn about and get lung cancer screening. It uses a health education approach to guide you through the process.
Carrboro, North CarolinaAges 50–80 - NCT06072690Recruiting
COPD and Heart Health Study
This study looks at how COPD affects your breathing and heart health. It is for people who are newly diagnosed with COPD and have a history of smoking.
Kaunas, Kaunas CountyAges 40 years+ - NCT06073431Recruiting
Study on weight loss types in advanced cancer
This study looks at different types of weight loss (cachexia) in people with advanced lung, pancreatic, or colorectal cancer. Researchers want to find patterns to better understand and treat it. You can join even if you haven't lost weight yet.
Fort Smith, ArkansasAges 18 years+ - NCT06073834Recruiting
Lung infection study in ICU patients
This trial tests a new way to better understand lung infections in very sick ICU patients. It looks at people with septic shock, severe trauma, or major burns to see if an infection is the cause.
LyonAges 18 years+ - NCT06074614Recruiting
Breathing and brain control in Parkinson's disease
This study looks at how the brain controls breathing in people with Parkinson's disease compared to healthy volunteers. It may help us understand breathing problems that can occur in Parkinson's.
Nijmegen, GelderlandAges 18 years+ - NCT06074380RecruitingPhase 4
Surfactant therapy comparison for preterm infants
This trial compares a new method of giving surfactant (a substance that helps babies' lungs work better) to preterm infants who have breathing problems. The goal is to see if giving surfactant through a thin tube without a breathing tube works as well as the usual method.
Evanston, IllinoisAges Up to 2 days - NCT06075524Recruiting
How PD-1 therapy affects immune cells in advanced cancers
This study looks at how your immune system responds to PD-1/PD-L1 immunotherapy (drugs like Keytruda or Opdivo) for advanced melanoma, lung cancer, and similar cancers. It involves regular blood tests to track your immune cells, which may help doctors understand why these treatments work for some people better than others.
Rochester, MinnesotaAges 18 years+ - NCT06076005Recruiting
Advanced Lung Cancer at First Diagnosis Study
This study collects information about people with advanced lung cancer at the time they are first diagnosed. It aims to understand the disease better and may help with future treatments.
RomaAges 18 years+ - NCT06076304RecruitingPhase 4
Comparing treatments for acute sinusitis
This trial tests whether nasal steroids, nasal irrigation, or oral antibiotics work best for acute sinusitis. It may help if you have ongoing sinus symptoms or a 'double-sickening' pattern after a cold.
Los Angeles, CaliforniaAges 18–75 - NCT06077643Recruiting
Support groups for people after voice box removal
This trial tests whether joining workshops and exchange groups helps people who have had their voice box removed (a total laryngectomy) feel better supported. You would attend four sessions at Bichat Hospital to share experiences and learn from others.
ParisAges 18 years+ - NCT06078969RecruitingPhase 2
Prednisone pills for bone LCH in children and teens
This trial tests whether taking a steroid pill (prednisone) by mouth can help children and teenagers with bone-only LCH. It is for people who do not need surgery and can swallow pills.
Shanghai, Shanghai MunicipalityAges 2–17 - NCT06080061RecruitingPhase 1
Personalized radiation and chemo for lung cancer
This trial is testing a personalized approach to giving radiation and chemotherapy together for lung cancer. It aims to make treatment more effective by tailoring the radiation schedule to each person.
Palo Alto, CaliforniaAges 18 years+ - NCT06079970Recruiting
Testing a microscope during lung biopsy
This trial tests if a special microscope (confocal laser endomicroscopy) used during a bronchoscopy can help doctors see and diagnose suspicious lung spots more clearly. It may help you if you have a small-to-medium sized spot in your lung that needs a biopsy.
New York, New YorkAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.