Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06545331RecruitingPhase 1
A study of XB010 for advanced solid tumors
This trial tests an investigational drug called XB010 for people with solid tumors that have spread or cannot be removed by surgery. It aims to see if XB010 is safe and effective for several cancer types, including lung, breast, head and neck, and esophageal cancers.
Irvine, CaliforniaAges 18 years+ - NCT06545747RecruitingPhase 3
MRI-guided radiation for advanced lung cancer
This trial tests a new way of giving radiation therapy for advanced lung cancer that cannot be surgically removed. It uses MRI scans to guide and adjust the radiation dose, which may help target the tumor more precisely and reduce side effects.
GuangzhouAges 18–75 - NCT06546007Recruiting
Blood and tissue markers to detect lung cancer early
This study is testing whether certain markers in your blood or tissue can help find lung cancer early. It is for people who have lung cancer that can be removed by surgery and haven't had treatment yet.
RomaAges 35–85 - NCT06547372Recruiting
Dietary changes for eczema relief
This study tests whether a specific diet can help manage mild to moderate eczema. It involves eating whole foods provided by the researchers for a set period and tracking your skin health.
Singapore, SingaporeAges 21–65 - NCT06547411Recruiting
Bariatric surgery and breathing machine settings study
This trial tests how different settings on the anesthesia machine affect people having weight-loss surgery. It aims to find the best way to manage breathing during the procedure.
Baotou, Inner MongoliaAges 16–65 - NCT06548386Recruiting
A new device to check for air leaks after lung surgery
This study is testing a new tool that checks for air leaks in the chest tube placed after lung surgery. An air leak can slow down recovery, and this device may help doctors detect it more accurately.
Evanston, IllinoisAges 18 years+ - NCT06548711Recruiting
Acupoint stimulation for cough after lung cancer surgery
This trial tests if a gentle electrical stimulation on your skin at specific points (acupoints) can help reduce a dry cough that lasts 2 weeks or more after lung cancer surgery.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT06549452Recruiting
Mobile health app to help teens with pulmonary hypertension exercise
This trial tests whether a smartphone app can help adolescents with pulmonary hypertension stay active and improve their health. If you are a teen with stable PH and can use an activity tracker, this study may be a good fit.
Nashville, TennesseeAges 10–21 - NCT06550219Recruiting
Using a face mask breathing support in premature babies with breathing trouble
This study tests whether delivering breathing support through a soft face mask (nasal non-invasive ventilation) can help premature babies who are having trouble breathing. Doctors will also use ultrasound to monitor their lungs.
AlexandriaAges 1 hour–1 day - NCT06551337RecruitingPhase 4
Vitamin D for bronchiectasis patients
This trial tests if taking vitamin D can help people with bronchiectasis have fewer flare-ups. It is only for patients who were in an earlier study that checked their vitamin D levels.
Hong KongAges 18 years+ - NCT06551441Recruiting
High-intensity interval training for lung disease
This study tests whether short bursts of intense exercise can improve heart and lung function in people with COPD (a chronic lung condition). It aims to see if this type of training is safe and effective.
CopenhagenAges 40–80 - NCT06552234RecruitingPhase 2
Study of repotrectinib for older or frail patients with ROS1-positive lung cancer
This trial tests an oral targeted therapy called repotrectinib in people with advanced non-small cell lung cancer (NSCLC) that has a change in the ROS1 gene. It is designed for patients who are either 70 or older, or have a lower performance status (ECOG 2 or higher), meaning they may be more frail or have more symptoms. The goal is to see if repotrectinib can help shrink or control the cancer.
Aix-en-Provence, Bouches Du RhôneAges 18 years+ - NCT06554522RecruitingPhase 4
Testing CPAP for Premature Babies with Breathing Problems
This trial tests a breathing support method called CPAP for premature babies with breathing problems in Africa. It may help your baby get better oxygen and avoid more invasive treatments.
BanguiAges 1 hour–1 day - NCT06554301RecruitingPhase 1
Empagliflozin for pulmonary arterial hypertension study
This study tests if the diabetes drug empagliflozin can help people with pulmonary arterial hypertension (PAH), a condition causing high blood pressure in the lungs. It aims to see if the drug improves symptoms and is safe for patients with moderate symptoms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06554353Recruiting
Breathing and exercise tests for shortness of breath
This study looks at how well two breathing tests work for people who have shortness of breath. You will do a breathing test and an exercise test to help doctors better understand your symptoms.
Rochester, New YorkAges 18 years+ - NCT06554496Recruiting
Xanthine Oxidoreductase Levels in New Sleep Apnea Patients
This study measures a substance called XOR in the blood of people who have just been diagnosed with obstructive sleep apnea but haven't started treatment yet. It aims to see if XOR levels are linked to sleep apnea.
Nanjing, JiangsuAges 18–80 - NCT06554613RecruitingPhase 2
Olanzapine with first-line immunotherapy for advanced lung cancer trial
This trial tests whether adding the drug olanzapine to standard first-line immunotherapy (with or without chemotherapy) can help people with advanced lung cancer that does not have an EGFR mutation. It aims to improve treatment outcomes and quality of life.
Nanchang, JiangxiAges 18–75 - NCT06556693Recruiting
Study of a new device for severe sleep apnea
This study tests if a new device can help people with severe sleep-disordered breathing (like sleep apnea). It may be an option if you have no or well-managed heart failure and are able to follow study procedures.
Scottsdale, ArizonaAges 22 years+ - NCT06556797Recruiting
A study to better understand shortness of breath using a CO2 test
This trial looks at whether a new way of measuring carbon dioxide (CO2) in the blood can help doctors quickly understand why a patient is short of breath. It is for adults who come to the emergency room with trouble breathing, and it involves doing an extra analysis on a blood sample that would be taken anyway.
BobignyAges 18 years+ - NCT06557343Recruiting
Lung Cell Study After Chest Radiation
This study looks at cells from the lungs of people who developed lung inflammation after chest radiation for cancer. It aims to understand why some people get this reaction, which may help find better treatments.
EdinburghAges 18 years+ - NCT06559956Recruiting
Comparing two ways to adjust Inspire therapy settings
This trial compares two methods of adjusting the Inspire device settings for sleep apnea. One method uses an overnight sleep study, the other a daytime study. The goal is to see if the daytime method works just as well.
Edegem, AntwerpAges 18–99 - NCT06560255RecruitingPhase 3
Fish oil in pregnancy to prevent childhood asthma
This study tests if taking fish oil during pregnancy can help lower the risk of childhood asthma. If you have low omega-3 levels, you may be randomly assigned to receive fish oil or a placebo.
Gentofte MunicipalityAges 18–45 - NCT06561295Recruiting
Best time for breathing trials in ventilated patients
This study looks at the best time to do a breathing trial for patients on a ventilator. It helps doctors decide when to start testing if you can breathe on your own so you can come off the ventilator sooner.
Chicago, IllinoisAges 21 years+ - NCT06561685RecruitingPhase 1
Study of LY4050784 for Advanced Solid Tumors with SMARCA4 Changes
This trial tests a new drug, LY4050784, for people with advanced solid tumors that have a specific change in a gene called SMARCA4 (BRG1). The study aims to see if the drug is safe and effective. It may be an option for those who have tried other treatments or have no standard options left.
Santa Monica, CaliforniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.