Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06849570Recruiting
Tailoring breathing support and muscle relaxants during prone positioning for severe lung injury
This trial tests two ways to adjust ventilator settings for patients with severe lung injury whose oxygen levels are very low. It aims to find out the best level of breathing support and whether giving muscle relaxants during prone positioning helps improve oxygen levels.
Aix-en-ProvenceAges 18 years+ - NCT06851195Enrolling by invitation
Electrical stimulation for leg strength in COPD
This trial tests whether a gentle electrical stimulation applied to your leg muscles can help you feel less breathless and less tired during daily activities, and improve your confidence in exercising. It is for people with stable COPD who are already in a pulmonary rehab program.
Kaohsiung, TaiwanAges 18 years+ - NCT06854627Recruiting
Comparing two ways of lying face down for ARDS patients
This study compares lying face down continuously for a long time versus lying face down for shorter periods each day. It is for patients with moderate to severe ARDS (a serious lung condition) who are on a breathing machine. The goal is to see which approach helps the lungs recover better.
Buenos AiresAges 18 years+ - NCT06849596Recruiting
Breathing help for extremely premature babies at birth
This study compares two ways to help extremely premature babies breathe right after birth: using a manual T-piece or a ventilator. The goal is to find which method is safer and more effective.
Los Angeles, CaliforniaAges 6 months–7 months - NCT06853145RecruitingEarly Phase 1
Using a special MRI scan to study lung disease in IPF
This trial uses an advanced MRI technique with a special gas (hyperpolarized xenon-129) to look at lung function in people with idiopathic pulmonary fibrosis (IPF). It may help doctors better understand how the disease affects your lungs and could lead to improved care.
Charlottesville, VirginiaAges 18 years+ - NCT06852053Recruiting
New tool to predict breathing pauses in premature babies
This study is testing a new tool that may help predict when babies born very early might have breathing pauses or slow heart rates. By using this tool, doctors hope to better monitor and care for your baby.
Birmingham, AlabamaAges 5 months–7 months - NCT06848751Recruiting
Tubeless lung surgery for patients with weak lungs
This trial tests whether a tubeless surgery technique (no breathing tube during or after surgery) is safe and effective for people whose lungs are not working well. If you need lung surgery and have trouble breathing, this approach might help you avoid a breathing tube and a stay in the ICU.
Jinan, ShandongAges 14–85 - NCT06851403Enrolling by invitation
Dupilumab for children with asthma in China
This study looks at how well and how safely the medicine Dupilumab works for children whose asthma is not well-controlled with their current inhalers. The goal is to see if it can help reduce asthma attacks and improve daily life.
Guangzhou, GuangdongAges 4–16 - NCT06848738Enrolling by invitation
Faster biopsy for lung cancer or lymphoma near the esophagus
This trial tests a faster way to get a tissue sample from lung cancer or lymphoma tumors that are near the esophagus or stomach. The goal is to start your treatment sooner by using a special ultrasound scope to do a biopsy right away.
NæstvedAges 18 years+ - NCT06851663RecruitingPhase 2/Phase 3
New PET scan for many solid tumors
This trial tests a new type of PET scan that uses a special antibody to find a marker called Trop2 on many common solid tumors. It may help doctors see tumors more clearly without needing a biopsy.
ShanghaiAges 18–75 - NCT06850298Recruiting
H5N1 milk detection study
This study looks for the H5N1 virus in the milk of healthy adults. If you are generally healthy and between 18 and 64, you may be able to help by providing milk samples to see if the virus can be detected.
Atlanta, GeorgiaAges 18–64 - NCT06847061Recruiting
Pulmonary rehab for rural COPD patients
This study tests a home-based or remote pulmonary rehabilitation program for people with COPD who live in rural areas. The goal is to help you manage your breathing and stay active, all from home without travel to a medical center.
Scottsdale, ArizonaAges 40 years+ - NCT06853223RecruitingPhase 2
Immune drug to prevent lung transplant failure
This trial tests an immune-suppressing medicine to stop a serious complication called primary graft dysfunction that can happen soon after a lung transplant. It may help people who are already on the transplant waiting list and plan to receive a standard anti-rejection drug regimen.
San Francisco, CaliforniaAges 18 years+ - NCT06855329Recruiting
Studying progressive lung scarring (non-IPF)
This study is for people with a specific type of lung scarring (not IPF) to understand how the disease progresses. Researchers will collect detailed health information, imaging, and blood samples to learn more about the condition.
Aurora, ColoradoAges 18–80 - NCT06853483Enrolling by invitation
School program to help parents quit smoking
This trial tests if a school-based program can help parents stop smoking. If you are a parent who smokes at least one cigarette a day and your child is in primary 4 (4th grade), this program may offer support to help you quit.
Wuhan, HubeiAges Any age - NCT05689476Recruiting
Measuring diaphragm breathing signals during ICU ventilation
This study measures electrical activity of the diaphragm and how your breathing system works while you are on a breathing machine in the ICU. It may help doctors better understand breathing during recovery after major lung events.
Padova, ItalyAges 18 years+ - NCT06753214Recruiting
Telemedicine training for caregivers to improve child asthma control
This trial tests if teaching caregivers about asthma care through telemedicine can help children with uncontrolled asthma feel better. It is designed for children whose asthma is not well-controlled and who are already being treated at a hospital clinic.
Can ThoAges 4–16 - NCT06232083RecruitingPhase 1
Study of Caronizumab with low-dose radiation for certain cancers
This trial tests a combination of an immunotherapy drug (Caronizumab) and a special type of low-dose radiation (PLDR) for people with esophageal, lung, or cervical cancer that has come back or spread after initial treatment. It aims to see if the combination can help stop the cancer from growing.
Hefei, British ColumbiaAges 18–75 - NCT06841055RecruitingPhase 2
Pumitamig plus chemo for Stage IV lung cancer after immunotherapy
This trial tests a new investigational drug called Pumitamig (BNT327) given with chemotherapy for people with advanced non-small cell lung cancer (Stage IV) that has continued to grow after one prior treatment with immunotherapy and platinum chemotherapy. The study aims to see if this combination is safe and can help shrink the cancer.
Birmingham, AlabamaAges 18 years+ - NCT06841770RecruitingPhase 1
Testing a delivery device for spinal cord injury treatment
This trial tests a device that delivers a special cell therapy (LCTOPC1) into the spinal cord. It is for people with a recent or chronic spinal cord injury that is severe (no feeling or movement below the injury) or leaves some sensation but no movement.
Downey, CaliforniaAges 18–65 - NCT06843018RecruitingPhase 2
Spray vs lozenge for sore throat from infection
This trial tests a new spray with anesthetic for sore throat caused by infections like pharyngitis. It compares the spray to a lozenge (Septolete Total) to see which works better and is safer.
Engel'sAges 18–75 - NCT06838273RecruitingPhase 3
Testing a new drug combo for EGFR-mutated lung cancer
This trial tests a new combination of two drugs (BL-B01D1 and osimertinib) versus osimertinib alone as the first treatment for people with a specific type of advanced lung cancer that has an EGFR mutation. The goal is to see if the combination works better at stopping the cancer from growing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT06577558RecruitingPhase 2
SR1375 for severe pneumonia not improving on antibiotics
This trial tests a new drug called SR1375 for adults with severe community-acquired pneumonia (a lung infection) who are not improving with standard antibiotics. It may help reduce inflammation and speed up recovery.
Fuyang, AnhuiAges 18–85
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.