Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06835569RecruitingPhase 1
ALTA3263 for advanced KRAS-mutated solid tumors
This trial tests an experimental pill called ALTA3263 for adults with advanced solid tumors that have a specific KRAS mutation. It's for people who have already tried other treatments or can't take them.
Orlando, FloridaAges 18 years+ - NCT06827379Enrolling by invitation
Breathing exercise for muscle and nerve health in COPD
This trial tests whether a special breathing exercise (inspiratory muscle training) can improve how your muscles work and your body's automatic responses, like heart rate. It's a one-time session for people with stable COPD.
João Pessoa, ParaíbaAges 40–75 - NCT06830694RecruitingPhase 2
Trial of a new drug combo for a rare type of lung cancer
This trial tests a new drug (tarlatamab) combined with chemotherapy and immunotherapy for people whose lung cancer has changed from one type (adenocarcinoma) to small cell lung cancer after treatment with EGFR targeted therapy. The goal is to see if this combination is safe and works well.
Seoul, Gangnam-guAges 19 years+ - NCT06828835Recruiting
Sleep study for caregivers of children with breathing problems
This study helps parents of children with sleep-related breathing problems (like snoring or pauses in breathing) who have been referred to a specialist. It offers support and guidance over 12 months to make it easier to get the care your child needs.
Charleston, South CarolinaAges 2–12 - NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+ - NCT06825819Recruiting
Dysbiosis and long COVID study
This study looks at gut bacteria changes in people with and without long COVID symptoms after a confirmed COVID infection. It may help find why some people have long-term health problems.
Chicago, IllinoisAges 18–80 - NCT06834971Recruiting
Inhaled colistin to prevent pneumonia in ventilated patients
This trial tests if inhaling a medication called colistin can prevent ventilator-associated pneumonia (a lung infection) in patients who are on a breathing machine. It aims to reduce the risk for those at high risk of getting an infection from drug-resistant bacteria.
Jinan, ShandongAges 18 years+ - NCT06827470RecruitingPhase 1
Whooping cough infection study in healthy adults
This study tests what happens when healthy adults are exposed to a special type of whooping cough bacteria. Results may help develop better vaccines to protect people from this infection.
Halifax, Nova ScotiaAges 18–50 - NCT06830109RecruitingPhase 2
Testing a nasal spray for stuffy nose relief
This study tests if a combination of two nasal sprays (a decongestant and a steroid) can help people with chronic nasal blockage who haven't gotten relief from steroid sprays alone.
St Louis, MissouriAges 18 years+ - NCT06833229Recruiting
Can a PET scan predict if immunotherapy is working?
This study uses a special PET-CT scan early in your treatment to see if immunotherapy (with or without chemotherapy) is working against your advanced lung cancer. The goal is to find out faster if the treatment is helping.
NiceAges 18 years+ - NCT06826794Recruiting
VentilO study for heart surgery patients on ventilators
This study tests a new way to monitor breathing in patients who are on a ventilator right after heart surgery. It may help doctors adjust settings more accurately.
Québec, QuebecAges 18 years+ - NCT06830174Recruiting
tDCS Brain Stimulation for Laryngeal Dystonia
This study tests whether a gentle brain stimulation technique called tDCS can help improve voice control in people with laryngeal dystonia. It aims to find a new way to reduce muscle spasms in the voice box.
New Haven, ConnecticutAges 18–65 - NCT06832163Recruiting
Smart weaning from inhaled nitric oxide for newborns with PPHN
This trial tests a new, smart way to slowly reduce (wean) the inhaled nitric oxide gas that helps babies with a serious lung condition called PPHN. If your baby is already responding well to iNO and needs it for at least 24 hours, this study might help make the weaning process safer and more effective.
ShanghaiAges Any age - NCT06117683Recruiting
Testing a new breathing device during planned surgery
This trial compares a new breathing device (used with a hand-held bag) to a standard breathing machine during planned surgeries. Researchers want to see if the new device works just as well for people under general anesthesia.
Providence, Rhode IslandAges 18–80 - NCT05455034RecruitingPhase 1/Phase 2
Blood and lung-sample test to guide treatment for lung inflammation
This Phase 1/2 study uses detailed “single-cell” testing (from lung samples) to better understand why lung inflammation happens after cancer radiation or immunotherapy. It aims to help choose the right treatment approach for people with radiation pneumonitis or immune checkpoint inhibitor pneumonitis.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT06128148RecruitingPhase 1
Study of JYP0322 for ROS1 fusion-positive solid tumors
This trial tests an experimental drug called JYP0322 for people with advanced solid tumors that have a specific genetic change called a ROS1 fusion. The goal is to see if the drug is safe and effective against these tumors.
Guangzhou, GuangdongAges 18 years+ - NCT05332067RecruitingPhase 2
Omalizumab to prevent future asthma flare-ups before they start
This trial studies whether starting omalizumab before asthma flare-ups begin can reduce how often children get worsening asthma that needs strong steroid medicine. It is for children with persistent asthma who have signs of allergic/asthma triggers and recent flare-up history.
Washington D.C., District of ColumbiaAges 6–17 - NCT05486650Recruiting
Study of focused radiation after PD-1 treatment helped non-lung cancer
This observational study looks at how stereotactic (high-precision) radiation works for advanced non-small cell lung cancer that is stable after PD-1 antibody treatment (sometimes with chemotherapy). It may help doctors better understand which patients benefit from this next treatment step and what side effects to expect.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05754203Recruiting
Radiation plus immunotherapy for advanced lung cancer
This trial studies whether a more intensive form of targeted radiation, combined with immunotherapy (immune checkpoint inhibitors), can work better and be safe for people with advanced non-small cell lung cancer. You may be considered if your tumor is limited in size and you’re able to receive both treatments.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06625944Recruiting
How viral infections affect lung disease
This study looks at how viral infections impact people with chronic lung conditions like COPD or bronchiectasis. It aims to understand symptoms and triggers better, which could help improve future treatments.
LondonAges 18 years+ - NCT06824506Recruiting
Ultrasound for lung issues after low-flow anesthesia
This trial tests if using ultrasound to check the lungs during low-flow anesthesia can help prevent breathing problems after gallbladder surgery. It may help doctors spot lung issues earlier and adjust care.
AnkaraAges 18 years+ - NCT06821126RecruitingPhase 1/Phase 2
Nasal spray COVID-19 vaccine booster study for healthy adults
This study tests a new nasal spray COVID-19 vaccine to see how it compares to an mRNA booster shot. It is for healthy adults who have already had at least 3 doses of an mRNA COVID-19 vaccine (or 2 doses plus a confirmed COVID infection) and are looking for a needle-free booster option.
DijonAges 18–60 - NCT06820749Enrolling by invitationPhase 2
Study of HSK31858 tablets for lung mucus conditions
This trial tests an investigational tablet for people with chronic lung diseases like bronchiectasis, COPD, or asthma who produce at least 10 mL of sputum (mucus coughed up from the lungs) each day. The goal is to see if the drug safely reduces excess airway mucus.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06816992RecruitingPhase 1
ORIC-114 with amivantamab for EGFR exon 20 insertion lung cancer
This trial tests an experimental pill (ORIC-114) combined with a targeted injection (amivantamab) for a specific type of non-small cell lung cancer that has an EGFR exon 20 insertion mutation. It aims to see if the combination shrinks tumors or delays growth.
New York, New YorkAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.