Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06562920RecruitingPhase 2
Immunotherapy plus chemo and SBRT before surgery for limited-stage small cell lung cancer
This trial tests a combination of immunotherapy (adebrelimab), chemotherapy, and targeted radiation (SBRT) before surgery for people with limited-stage small cell lung cancer. The goal is to see if this approach can shrink tumors and improve outcomes before the main treatment.
Hangzhou, ZhejiangAges 18–75 - NCT06563388RecruitingPhase 3
SABR for limited metastatic cancer (ID-COMET trial)
This study tests a precise radiation technique called SABR to treat cancer that has spread to a few spots. It aims to see if this approach can help control the cancer better than usual treatment, especially for lung, prostate, colorectal, or other solid tumors with limited spread.
Buffalo, New YorkAges 1 year+ - NCT06563674Recruiting
Healthy lifestyle program for lung disease patients
This trial tests a program that helps people with pneumoconiosis (a lung disease from dust exposure) build healthy habits. It may provide support to improve your quality of life.
Hong KongAges 18 years+ - NCT06563999RecruitingPhase 2
Study of new drugs for stage III lung cancer with rare gene changes
This trial tests whether giving treatment before surgery (neoadjuvant therapy) can help people with stage III lung cancer that has certain rare gene changes. The goal is to see if this approach can shrink the tumor enough to allow surgery.
Guangzhou, GuangdongAges 18–75 - NCT06564324RecruitingPhase 3
Comparing taletrectinib to standard therapy for ROS1-positive lung cancer
This study compares a new targeted therapy pill (taletrectinib) to standard treatments for people with advanced ROS1-positive lung cancer. The goal is to see if taletrectinib works better at shrinking tumors and delaying cancer growth.
Hefei, AnhuiAges 18 years+ - NCT06566079RecruitingPhase 1
Study of ISM6331 for advanced mesothelioma or other solid tumors
This trial tests an experimental drug called ISM6331 for people with advanced mesothelioma or other solid tumors that have not responded to standard treatments. The drug targets a specific cell pathway (Hippo) that may be involved in tumor growth.
Denver, ColoradoAges 18 years+ - NCT06566443RecruitingPhase 1
Honokiol for early-stage lung cancer before surgery
This trial tests a natural compound called honokiol in people with early-stage non-small cell lung cancer who are scheduled for surgery. The goal is to see if honokiol can help shrink or control the tumor before it is removed.
Houston, TexasAges 18 years+ - NCT06566898Recruiting
Tracking antibiotic resistance in pneumonia patients
This study uses advanced genetic testing to monitor antibiotic-resistant bacteria in people with pneumonia. It aims to understand how resistance develops and improve treatment choices.
Shanghai, Shanghai MunicipalityAges Any age - NCT06567379Recruiting
Heart function study in pulmonary arterial hypertension
This trial uses special ultrasound imaging to look at how well the heart works in people newly diagnosed with pulmonary arterial hypertension (PAH). It aims to understand heart changes before and after starting PAH treatment.
NancyAges 19 years+ - NCT06567717RecruitingPhase 2
Zinc and vitamin B3 supplement for IPF
This trial tests whether adding zinc and nicotinamide riboside (a vitamin B3-like supplement) to standard IPF treatment can help improve lung function. It is for people with IPF who are already seeing a lung doctor and live in certain states.
Los Angeles, CaliforniaAges 50 years+ - NCT06567977Recruiting
TriMaximize: A study of a triple therapy inhaler for asthma
This study is looking at how well a triple therapy inhaler (Trimbow®) works for people with asthma, including those who also have COPD. It aims to see if starting this treatment helps control symptoms and improve quality of life in everyday medical practice.
Tarnowskie GóryAges Any age - NCT06568159Recruiting
Sleep apnea treatment in heart patients
This study looks at how well people with heart disease or high heart risk follow their sleep apnea treatment, comparing a mouth device (MAD) to a CPAP machine. It aims to find which treatment works better for daily use.
MontpellierAges 18 years+ - NCT06569940Recruiting
Contactless sleep monitoring device vs standard monitors
This study compares a new contactless device (Sleepiz One+) to standard equipment that measures breathing and heart activity. It is for adults both with and without chronic health conditions.
Zurich, Canton of ZurichAges 18 years+ - NCT06570473RecruitingPhase 2
RV failure treatment trial for pulmonary hypertension patients
This trial is testing two heart medications, empagliflozin and ranolazine, to see if they can improve right heart function in people with pulmonary hypertension and right ventricular failure. Participants will monitor their symptoms using a smartphone or tablet.
Calgary, AlbertaAges 18 years+ - NCT06570317Recruiting
Nintedanib to prevent lung inflammation from radiation
This trial tests a drug called nintedanib to see if it can prevent radiation-related lung inflammation (pneumonia) in people with lung cancer that cannot be surgically removed. It may help protect your lungs during radiation treatment.
Jincheng, ShanxiAges 18 years+ - NCT06570616Recruiting
Reducing mask leaks during CPAP for sleep apnea
This study tests a method to help CPAP users with nasal masks who have high air leaks. It aims to find better ways to reduce unintentional leaking so treatment works more effectively.
São Paulo, BrazilAges 18 years+ - NCT06570629Recruiting
Fixing air leaks with nasal CPAP
This trial looks at ways to fix air leaks that happen when using a CPAP mask at night. It may help if you have sleep apnea and your CPAP is leaking a lot despite using a nasal mask.
São Paulo, BrazilAges 18 years+ - NCT06570889RecruitingPhase 3
Vitamin D in pregnancy to prevent early childhood asthma
This trial tests if taking extra vitamin D during pregnancy can prevent asthma in young children. It is for pregnant women in Denmark who already have certain healthy fat levels in their blood.
Gentofte MunicipalityAges 18–45 - NCT06571136Recruiting
Can a breath test detect COVID-19?
This study tests a new device that measures chemicals in your breath to see if it can quickly tell if you have COVID-19. If successful, it could lead to a fast, non-invasive way to check for the virus.
Everett, WashingtonAges 18–70 - NCT06571942RecruitingPhase 4
Triple therapy for lung disease from biomass smoke
This trial is testing a combination of three inhaled medicines (triple therapy) to see how well they help the small airways in people whose lung disease is caused by breathing in smoke from cooking or heating with wood or other biomass fuels. It may be a good fit if you have COPD or chronic bronchitis from this type of exposure.
Mexico City, TlalpanAges 35–85 - NCT06572384RecruitingPhase 3
Belimumab for lung scarring in autoimmune disease
This study tests whether a drug called belimumab can help people with lung scarring caused by certain autoimmune diseases (like rheumatoid arthritis or lupus). If you have active lung disease despite standard therapy, this trial may be an option.
Los Angeles, CaliforniaAges 18 years+ - NCT06572540Recruiting
Cryoablation for early-stage lung cancer
This trial compares two ways to freeze and destroy small lung tumors: through the chest wall or through the airways. It’s for people with early-stage lung cancer who are not able or willing to have surgery.
Guangzhou, GuangdongAges 18 years+ - NCT06573008RecruitingPhase 3
Testing GP681 Tablets for Flu in High-Risk Patients
This study tests an oral tablet called GP681 for people with flu who are at higher risk of serious complications. It compares the new drug to a placebo to see if it helps reduce symptoms faster.
ChizhouAges 12 years+ - NCT06573073Recruiting
Lung cancer test for EGFR T790M mutation
This trial tests a new blood test that can detect a specific genetic change (EGFR T790M) in advanced lung cancer. It aims to see if the test works well for guiding treatment decisions.
TaipeiAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.