Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06782724RecruitingPhase 2
Psilocybin therapy for distress in advanced illness
This trial tests whether a single dose of psilocybin (a psychedelic medicine) can help reduce depression and distress in people with advanced lung disease, ALS, multiple sclerosis, or Parkinson's. You would receive preparation, the drug, and follow-up support in a safe, supervised setting.
PragueAges 18 years+ - NCT06783998Enrolling by invitation
Breathing muscle health in sleep apnea
This trial studies how sleep apnea affects the muscles you use to breathe. It may help doctors better understand and treat breathing problems in people with sleep apnea.
Mersin, MersinAges 18 years+ - NCT06784492Recruiting
Healthy living tips after a pulmonary embolism
This study tests whether healthy living tips and messages sent daily by text or email can help you recover better after a serious blood clot in your lung called a pulmonary embolism. It may be a good fit if you are already taking a blood thinner and can receive text messages.
Rochester, New YorkAges 18 years+ - NCT06789770Recruiting
Nasal vs mouth breathing during drug-induced sleep
This study compares how breathing through the nose versus mouth affects sleep, using both natural and medication-induced sleep. It may help people with sleep apnea understand their breathing patterns better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06792045Recruiting
Predicting tongue blockage during sleep in children
This study uses a special camera during sleep to see if the tongue is blocking the airway in children with sleep-disordered breathing. It may help doctors better understand why some children still have trouble breathing after tonsil surgery.
BrusselsAges 6–17 - NCT06784037Enrolling by invitation
Best lung pressure during robotic lung surgery
This trial tests the best setting for air pressure in the lungs during robotic lung surgery without capnothorax. It aims to improve breathing and recovery after surgery.
Barcelona, CataloniaAges 18 years+ - NCT06786117Enrolling by invitation
Swallowing therapy study for sleep apnea patients
This study tests whether daily swallowing exercises can help people with sleep apnea who cannot tolerate CPAP therapy. It compares three groups: healthy people, successful CPAP users, and those who have difficulty using CPAP.
Cleveland, OhioAges 40–70 - NCT06789692Recruiting
Reducing tobacco use in people with HIV
This study combines a medication to help people stop smoking with a custom mobile app, all within the Swiss HIV Cohort Study. It's designed for people living with HIV who smoke and want to quit.
Basel, BaselAges 18 years+ - NCT06788093Recruiting
Reducing antibiotic overuse with decision support
This trial tests a tool to help doctors decide when antibiotics are truly needed for lung infections like bronchitis or pneumonia. It may help you avoid unnecessary antibiotics and their side effects.
Oakland, CaliforniaAges 6 months–17 years - NCT06792617Enrolling by invitationEarly Phase 1
Exercise for people on ECMO life support
This study tests if gentle exercise in bed can help people on ECMO (a life-support machine for heart and lungs) get stronger and recover faster. It is for adults in the ICU who are stable enough to move safely.
San Antonio, TexasAges 18 years+ - NCT06785272RecruitingPhase 3
Magnesium for children with asthma in the ER
This trial tests if giving magnesium sulfate through an IV helps children with moderate to severe asthma attacks in the emergency department. If your child is between 2 and 17 years old and still has trouble breathing after three puffs of standard asthma medicine, this study may be an option.
Calgary, AlbertaAges 2–17 - NCT06784791RecruitingPhase 2
Amivantamab before surgery for EGFR-mutant lung cancer
This trial tests a new drug, amivantamab, given before surgery for people with a specific EGFR-mutated lung cancer. It aims to shrink tumors and improve surgical outcomes, and may be combined with standard chemotherapy in some patients.
HasseltAges 18 years+ - NCT06506474Recruiting
A study on care for babies hospitalized with bronchiolitis
This trial looks at how doctors treat babies hospitalized with bronchiolitis. It aims to understand which treatments are really needed and where care could be improved. If your baby was recently admitted for bronchiolitis, this study might help future babies get better, simpler care.
Calgary, AlbertaAges 4 weeks–1 year - NCT06062823RecruitingPhase 2
Newer EGFR pill for advanced lung cancer with specific mutations
This trial tests a newer type of EGFR targeted therapy pill for people with advanced non-small cell lung cancer who have not had prior treatment and whose cancer has a specific genetic change called a PACC mutation. The goal is to see if the drug works well for this group.
SingaporeAges 21–99 - NCT06301841Recruiting
Antibiotic choice for COPD with pneumonia in ICU
This trial is testing a new way to choose antibiotics for people with COPD who get pneumonia and need intensive care. The goal is to find the best treatment using a personalized approach.
CaenAges 18 years+ - NCT06734702RecruitingPhase 3
Immunotherapy before chemo-radiation for advanced lung cancer
This trial tests a new approach for people with stage III lung cancer that cannot be removed with surgery. You would receive immunotherapy (to help your immune system fight cancer) plus chemotherapy first, then standard chemo-radiation, and finally more immunotherapy. The goal is to see if this sequence works better than standard treatment.
Guangzhou, GuangdongAges 18–75 - NCT06780046Recruiting
COPD study for Brazilian patients
This study looks at the health of Brazilian adults with COPD. It aims to understand how the condition affects people and may help improve future treatments.
Aparecida de GoiâniaAges 18 years+ - NCT06780137RecruitingPhase 1/Phase 2
Gocatamig plus ifinatamab deruxtecan for advanced small cell lung cancer
This study tests two new drugs (gocatamig and ifinatamab deruxtecan) for people whose small cell lung cancer has spread or come back after standard chemotherapy. It aims to see if the combination works better than current options.
Aurora, ColoradoAges 18 years+ - NCT06780098RecruitingPhase 2
Study of new treatments for advanced squamous lung cancer
This trial tests new drugs for people with advanced squamous non-small cell lung cancer that has gotten worse after standard treatments like immunotherapy and chemotherapy. The goal is to find better options for those who need them.
Lexington, KentuckyAges 18 years+ - NCT06778863RecruitingPhase 1
A study of CLSP-1025 for adults with certain solid tumors
This trial tests a new drug called CLSP-1025 for people with advanced solid tumors that have a specific change in the p53 gene (R175H). The drug targets this change to help fight the cancer.
Scottsdale, ArizonaAges 18 years+ - NCT06780085RecruitingPhase 2
Study of new drugs for advanced lung cancer
This trial tests new treatments for people with stage IV nonsquamous non-small cell lung cancer that has gotten worse after prior immunotherapy and chemotherapy. It aims to find better options for those whose cancer has specific genetic features.
Lexington, KentuckyAges 18 years+ - NCT06774963RecruitingPhase 1
Study of LNCB74 for advanced solid tumors
This trial tests a new drug called LNCB74 for people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and effective.
Newport Beach, CaliforniaAges 18 years+ - NCT06775743RecruitingPhase 2
Combination therapy and radiation for EGFR-mutant lung cancer after resistance
This trial tests whether adding radiation therapy to a drug combination can help people with a specific type of lung cancer that has stopped responding to standard first-line pills. It's for patients whose cancer has a certain gene change (EGFR) and has spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06778746Recruiting
Study of Biologics for Severe Asthma in Hong Kong
This study looks at how biologic medicines (special injections or infusions) are used to treat severe asthma in Hong Kong. It may help researchers understand why some people stop or switch these treatments.
Hong KongAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.