Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT07670494Recruiting
Comparing breathing machine settings during laparoscopic gallbladder surgery
This study compares different ways of using a breathing machine during laparoscopic gallbladder surgery. It looks at how much pressure is put on the lungs to find the safest and most effective method for people having this type of surgery.
Yenimahalle, AnkaraAges 18 years+ - NCT07235098Recruiting
Music therapy for lung cancer surgery patients
This trial tests whether listening to music in the hospital can help reduce distress and pain after surgery for lung cancer. If you are having a minimally invasive surgery (keyhole surgery) to remove part of your lung, you may be able to join.
Bellinzona, Canton TicinoAges 18 years+ - NCT06600919Recruiting
Music therapy app for anxiety before ENT surgery
This study tests whether listening to calming music through a phone app before ENT surgery can help prevent anxiety. It is for adults who are scheduled for ear, nose, or throat surgery.
Saint-DenisAges 18 years+ - NCT06601998Recruiting
Heart health after severe pneumonia
This study looks at how heart health changes in people who have recovered from severe pneumonia, including COVID-19. It compares survivors to healthy people and those with heart risk factors.
AlexandroupoliAges 18 years+ - NCT06602869Recruiting
Cellular markers in cystic fibrosis with a certain lung infection
This study looks at special blood markers in people with cystic fibrosis who have or haven't been treated for a lung infection caused by nontuberculous mycobacteria. The goal is to better understand the body's response, which could lead to better treatments.
MontpellierAges 18 years+ - NCT06603246RecruitingPhase 1
Study of inhaled GDC-6988 for mucus lung diseases
This study tests an inhaled medicine (GDC-6988) to see if it is safe and helps clear mucus from the lungs in people with mucus-related lung diseases like chronic bronchitis, COPD, or bronchiectasis. You may qualify if your lung function is fairly stable and you produce daily mucus.
Birmingham, AlabamaAges 18 years+ - NCT06604689Recruiting
AI-guided brain radiation for EGFR-mutant lung cancer with brain mets
This study uses AI to help doctors decide the best way to use brain radiation for people with EGFR-mutant lung cancer that has spread to the brain. It aims to improve treatment planning and outcomes for those already taking a third-generation targeted therapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06605404Recruiting
Pan-tumor study of a blood test after cancer surgery
This study is testing a new blood test that looks for leftover cancer cells after surgery. It is for people with different types of solid tumors who are planning to have surgery to cure their cancer. The goal is to see if the test can help guide future treatment decisions.
San Diego, CaliforniaAges 18 years+ - NCT06605534Recruiting
Lung cancer screening study for current and past smokers
This study uses the emergency department to offer lung cancer screening to people who smoke or recently quit. It aims to catch lung cancer early, when it's easier to treat.
Brick, New JerseyAges 50–80 - NCT06605755Recruiting
Testing a pentavalent vaccine in 2-month-old babies
This trial tests a combined vaccine that protects against five diseases (diphtheria, tetanus, whooping cough, polio, and Hib) in 2-month-old babies who have already received 4 doses. It aims to check the vaccine's safety and how well it builds immunity.
Nanjing, JiangsuAges 1.6 years–1.8 years - NCT06605794Recruiting
FreeFlow heart shunt for severe idiopathic pulmonary hypertension
This trial tests a new device called FreeFlow, which creates a small opening in the wall between the top chambers of the heart to relieve pressure. It is for people with severe idiopathic pulmonary hypertension who still have serious symptoms despite standard medications.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06607770RecruitingPhase 1/Phase 2
Cryoablation with immunotherapy for multiple lung cancers
This trial tests freezing tumors (cryoablation) combined with two drugs (Karelizumab and Apatinib) for people who have several small lung cancer spots in their lungs but no spread to lymph nodes. The goal is to see if this combination is safe and helps shrink or control the tumors.
Guangzhou, GuangdongAges 18–75 - NCT06607796RecruitingPhase 3
PTS injection for stage 4 lung cancer without gene mutations
This trial tests injecting a drug called PTS directly into lung tumors for people with stage 4 non-small cell lung cancer that doesn't have certain gene changes. It is for patients whose tumors have stayed stable after first-line treatment and are located in a small area of the outer lung.
Guangzhou, GuangdongAges 18–75 - NCT06608160Recruiting
PET scan to tell if lung cancer is truly growing after immunotherapy
This trial uses a special PET scan (68Ga-grazytracer) to find out whether growth seen on scans after immunotherapy is real cancer growth or a harmless reaction called pseudoprogression. It helps doctors decide if your treatment is working.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06608849Recruiting
Long-term health effects after COVID-19
This study looks at how COVID-19 may affect the lungs, heart, and kidneys in the months or years after the infection. It compares three groups: people who never had COVID, people who had COVID but recovered without organ problems, and people who had organ problems during COVID. The goal is to understand what long-term complications might arise.
AthensAges 18 years+ - NCT06608888Recruiting
Brain chemical study for sleep apnea and snoring
This study looks at how a brain chemical called 5-HT7 affects sleep apnea by testing different groups: people with sleep apnea, people who snore, and healthy volunteers. It aims to find new ways to help regulate breathing during sleep.
Beijing, Beijing MunicipalityAges 20–60 - NCT06609577Recruiting
Ultrasound-guided diaphragm pacing for patients on ventilators
This trial tests a personalized pacing device that uses ultrasound to help your diaphragm muscle work better while you are on a breathing machine. It may help you breathe on your own sooner and improve your recovery.
Nantong, JiangsuAges 18–95 - NCT06609694Recruiting
Comparing oxygen delivery methods for children with sleep apnea
This study tests a new way to give oxygen to children aged 5-17 who have obstructive sleep apnea (a condition where breathing stops briefly during sleep). It aims to see if a demand oxygen delivery system works better than standard care. This could help children with Down syndrome who often have untreated sleep apnea.
Cincinnati, OhioAges 5–17 - NCT06609941Recruiting
Breathing technique plus standard treatment for asthma symptoms
This trial tests if adding a simple breathing exercise (alternate nostril breathing) to your regular asthma medicines can help reduce shortness of breath and improve your breathing control. It is for adults with mild to moderate asthma.
Rawalpindi, Punjab ProvinceAges 18–45 - NCT06611137RecruitingPhase 2
SBRT plus chemoimmunotherapy to save the voice box
This trial tests a new approach to treat advanced larynx or hypopharynx cancer without removing the voice box. First, you get targeted radiation (SBRT), then a combination of chemotherapy and an immunotherapy drug called Toripalimab, which helps your immune system fight the cancer.
Guangzhou, GuangdongAges 18–70 - NCT06611319RecruitingPhase 3
Shorter blood thinner after hip replacement: a recovery study
This study tests a shorter course of blood thinner medication (rivaroxaban) after hip replacement surgery, following an enhanced recovery plan. It aims to see if a shorter treatment can safely prevent blood clots and help you recover faster.
Linz, Upper AustriaAges 18–85 - NCT06611527Recruiting
Breathing therapy to improve lung function after heart surgery
This study tests a breathing treatment using mild air pressure after heart surgery to help your lungs work better and reduce complications. It may be an option for people at higher risk for lung problems or those with early breathing issues after surgery.
São Paulo, São PauloAges 18 years+ - NCT06611696RecruitingPhase 4
Avacopan vs lower-dose steroids for new vasculitis
This study compares a new drug (avacopan) with lower doses of steroids to standard steroid treatment for people newly diagnosed with ANCA-associated vasculitis. The goal is to see if avacopan can control your disease with fewer steroid side effects.
Toyoake, Aichi-kenAges 18 years+ - NCT06612294Recruiting
Asthma symptom perception study for older adults
This study looks at how older adults with asthma perceive their symptoms. It aims to improve understanding of asthma symptoms in people over 60 with uncontrolled asthma.
New York, New YorkAges 60 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.