Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06598527RecruitingPhase 3
Radiation and immunotherapy before surgery for lung cancer
This trial tests adding targeted radiation before standard immunotherapy and chemotherapy for people with stage 2-3 non-small cell lung cancer that can be surgically removed. The goal is to see if the radiation helps shrink the tumor more before surgery.
Guangzhou, GuangdongAges 18–75 - NCT06598306RecruitingPhase 1
Tarlatamab injection for advanced small cell lung cancer
This trial tests a new drug called tarlatamab, given as an injection under the skin (like a shot), for people with advanced small cell lung cancer that has worsened after chemotherapy. The goal is to see if this treatment can help shrink or slow down the cancer.
Los Angeles, CaliforniaAges 18 years+ - NCT06598839Recruiting
Immune effects of thymosin alpha-1 for stage I lung cancer
This trial tests whether thymosin alpha-1, an immune-boosting medicine, can help people with stage I non-small cell lung cancer after surgery. The goal is to see if it improves the immune system's response and recovery.
Beijing, Beijing MunicipalityAges 18–75 - NCT06598982Recruiting
Muscle Weakness in the Breathing Muscles in Scleroderma
This study looks at whether people with systemic sclerosis (scleroderma) have weakness in the muscles they use to breathe. It aims to find out if measuring these muscles can help detect early breathing problems.
Konya, SelcukluAges 18–75 - NCT06599658RecruitingPhase 2
COVID-19 booster and flu vaccine timing for people with weak immune systems
This study tests the best timing for a COVID-19 booster and flu shot in people with weakened immune systems, such as organ transplant recipients, people living with HIV, or those with certain autoimmune conditions. It aims to help patients get better protection from both vaccines.
Montreal, QuebecAges 18 years+ - NCT06599892Recruiting
Cystic fibrosis care with highly effective modulators
This study looks at how cystic fibrosis care is organized when patients take highly effective CFTR modulator drugs. It aims to understand if care needs change for those on modulators compared to those who cannot take them.
LyonAges 6 years+ - NCT06600126Recruiting
Emotional support for people with emphysema and their caregivers
This study tests a program that helps people with COPD (emphysema) who feel sad or down. You and a loved one will get weekly phone or video calls to learn ways to manage emotions and improve your quality of life.
Detroit, MichiganAges 18 years+ - NCT06600542Recruiting
Inari VISION registry for patients treated with Inari devices
This registry collects information on people who have already received treatment with an Inari Medical device, such as a catheter used to remove blood clots. It helps doctors learn more about how well these devices work over time.
AnconaAges 18 years+ - NCT06600646Recruiting
Study of energy production in airway cells for chronic cough
This study looks at how the cells lining your airways make energy and whether this is different in people with chronic cough that doesn't get better with treatment or has no clear cause. It may help doctors understand why some people cough and find new ways to treat it.
Hamilton, OntarioAges 18–80 - NCT04509050Recruiting
Testing a highly effective CF medicine in young children
This study looks at how well a highly effective cystic fibrosis (CF) medicine works in infants and young children, and what biological changes it causes. It may help families understand whether the medicine improves CF function and related measures early in life.
Birmingham, AlabamaAges Up to 10 years - NCT07314216RecruitingPhase 2
Firmonertinib plus radiation for stage III lung cancer with rare EGFR mutations
This trial tests whether combining the targeted pill firmonertinib with radiation therapy can help people with stage III non-small cell lung cancer that has certain rare EGFR mutations. It is for those whose cancer cannot be removed by surgery.
Changsha, HunanAges 18 years+ - NCT05543330RecruitingPhase 1/Phase 2
M701 for lung cancer with pleural effusion
This trial tests a new drug called M701 for people with non-small cell lung cancer that has spread to the lining of the lung, causing fluid buildup (pleural effusion). It aims to see if M701 can help control the fluid and improve symptoms.
Hangzhou, ZhejiangAges 18–75 - NCT05548283RecruitingPhase 4
Standard IV antibiotic timing for cystic fibrosis lung flare-ups
This study standardizes how IV aminoglycoside antibiotics are given during a 14-day treatment for cystic fibrosis (CF) lung flare-ups. It may help make treatment more consistent and easier to manage for people who need IV antibiotics.
Birmingham, AlabamaAges 6 years+ - NCT06139627Recruiting
Geriatric assessment for older adults with lung cancer getting chemotherapy and radiation
This trial tests whether a special geriatric assessment can help manage side effects for adults aged 60 and older with non-small cell lung cancer who are starting a new treatment plan that includes chemotherapy and radiation. It aims to improve quality of life and treatment outcomes.
Duarte, CaliforniaAges 60 years+ - NCT06103682Recruiting
Treating growing lung spots with local therapy
This trial tests if focusing treatment on a few new or growing lung tumors can help people with lung cancer who are already on systemic therapy. You may qualify if you have stable disease overall but a small number of new spots that can be safely treated with radiation or other local procedures.
Sacramento, CaliforniaAges 18 years+ - NCT07690345Recruiting
Fungal status and outlook in allergic bronchopulmonary aspergillosis
This study looks at how the presence of fungus in lung samples relates to the long-term outlook for people with allergic bronchopulmonary aspergillosis (ABPA). It aims to help doctors better understand the disease and guide treatment.
Jinan, ShandongAges 18 years+ - NCT07578012RecruitingPhase 4
Ismigen to prevent respiratory infections in children
This study tests whether a medicine called Ismigen can help children who get frequent respiratory infections (like colds, bronchitis, or throat infections) stay healthier. The medicine is made from bacterial components designed to strengthen the immune system.
BialystokAges 3–12 - NCT07546981RecruitingPhase 3
New Asthma Inhaler for People on Standard Therapy
This study tests a new three-part asthma inhaler (CHF 5993) in people whose asthma isn't well-controlled even though they're already using two standard asthma medicines together. The goal is to see if adding this new medicine helps control asthma better.
Beijing, Chaoyang DistrictAges 18–75 - NCT06743490Recruiting
Tracking MG symptoms with smartphone recordings
This study uses your smartphone to record symptoms like slurred speech, hoarseness, arm fatigue, or droopy eyelids, making it easier for doctors to understand and monitor myasthenia gravis. Both people with MG and healthy volunteers can take part.
Leiden, South HollandAges 18 years+ - NCT07242547RecruitingPhase 2
Tarlatamab maintenance for limited-stage small cell lung cancer
This trial tests a new immunotherapy medicine called tarlatamab given as maintenance therapy after initial treatment for limited-stage small cell lung cancer. It aims to keep the cancer from coming back.
Albacete, AlbaceteAges 18 years+ - NCT07101640RecruitingPhase 1/Phase 2
Montelukast study for breathing problems in premature infants
This trial tests if the medicine montelukast can help very premature babies on breathing machines. It aims to see if it improves lung development and makes it easier for them to breathe on their own.
Little Rock, ArkansasAges 1 week–4 weeks - NCT07097896Recruiting
Lung valve treatment for emphysema
This trial tests a small silicone valve placed in your airways to help you breathe better if you have emphysema. It may be an option if you have severe breathing problems and are not getting enough relief from medicine alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07566195RecruitingPhase 3
Long-term Safety of Tozorakimab in COPD Patients
This study follows patients who previously took part in a tozorakimab trial to see how safe the drug is over time. Tozorakimab is an antibody treatment designed to reduce flare-ups (exacerbations) in people with COPD, a chronic lung disease.
Aix-en-ProvenceAges 18–99 - NCT07530146RecruitingPhase 3
Sedation Medications for Older ICU Patients on Breathing Machines
This study compares two sedation medications—propofol alone versus propofol combined with ketamine—in older patients in the ICU who are on breathing machines due to infection or lung problems. The goal is to find which combination is safer and works better for keeping patients calm and comfortable.
CairoAges 65 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.