Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06775743RecruitingPhase 2
Combination therapy and radiation for EGFR-mutant lung cancer after resistance
This trial tests whether adding radiation therapy to a drug combination can help people with a specific type of lung cancer that has stopped responding to standard first-line pills. It's for patients whose cancer has a certain gene change (EGFR) and has spread to other parts of the body.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06778746Recruiting
Study of Biologics for Severe Asthma in Hong Kong
This study looks at how biologic medicines (special injections or infusions) are used to treat severe asthma in Hong Kong. It may help researchers understand why some people stop or switch these treatments.
Hong KongAges 18 years+ - NCT06776731Recruiting
Does extra oxygen during rehab help lung disease patients?
This study tests whether breathing extra oxygen during outpatient pulmonary rehabilitation helps people with COPD. Participants will have their oxygen levels checked during exercise to see if extra oxygen improves their rehab results.
Winterthur, Canton of ZurichAges 18 years+ - NCT06776939Recruiting
High-flow oxygen through trach tube to help weaning from a ventilator
This trial tests if high-flow oxygen delivered through a tracheostomy tube can make mucus less sticky and reduce breathing effort while you are being taken off a ventilator. It could help you breathe easier during weaning.
RotterdamAges 18 years+ - NCT06781905Recruiting
Brain effects of ALK/ROS1 lung cancer drugs and quality of life
This study looks at how certain targeted therapy drugs for ALK/ROS1-positive lung cancer may affect thinking, memory, mood, and mental health. It aims to build a special care and research path where patients and researchers work together to understand and manage these side effects.
BronAges 18 years+ - NCT06769126RecruitingPhase 2
Personalized treatment study for extensive stage small cell lung cancer
This study uses biomarker tests on your tumor to find a personalized treatment after initial chemotherapy. You will be assigned to one of four treatment groups based on your biomarker results.
Loma Linda, CaliforniaAges 18 years+ - NCT06762002Recruiting
Immune system study for people with certain immune weaknesses
This study is for adults whose immune system has trouble fighting viruses due to specific antibodies or a genetic condition. Researchers want to follow these people over time to better understand the condition and improve care.
LilleAges 18 years+ - NCT06769607Recruiting
New auto-CPAP algorithm for sleep apnea
This study tests a new, smarter way for your CPAP machine to automatically adjust air pressure while you sleep. If you have a ResMed AirSense 10 or 11 and have been using it for a few months, you may be eligible.
Bella Vista, New South WalesAges 18 years+ - NCT06762873RecruitingEarly Phase 1
Testing a nerve therapy for Latin Americans with sleep apnea
This trial tests a new nerve-stimulation therapy called Neuromod to treat moderate-to-severe sleep apnea in people who do not have access to other treatments. If you qualify, you would be part of a study to see if this implant helps improve your breathing during sleep.
AsunciónAges 18 years+ - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT06765109RecruitingPhase 3
Testing neladalkib for untreated ALK-positive lung cancer
This study tests a new pill called neladalkib to see if it works better than the current standard treatment (alectinib) for people with ALK-positive lung cancer who have not yet received any cancer therapy for advanced disease. It may be a good option if you have ALK-positive NSCLC and have not been treated before.
Glendale, ArizonaAges 18 years+ - NCT06767514RecruitingPhase 3
Ivonescimab for first-line treatment of advanced NSCLC with high PD-L1
This trial tests a new drug called Ivonescimab as the first treatment for people with advanced (stage IV) non-small cell lung cancer whose tumors have high levels of PD-L1 (a protein that helps cancer hide from the immune system). The goal is to see if it can help shrink or control the cancer.
Chandler, ArizonaAges 18 years+ - NCT06764771RecruitingPhase 1
Study of a new drug for advanced solid tumors
This trial tests a new investigational drug, BMS-986488, alone or with another drug (adagrasib), for people with advanced solid tumors that have not responded to other treatments. It aims to see if the drug is safe and works against certain cancers.
Hackensack, New JerseyAges 18 years+ - NCT06770023RecruitingPhase 1
Bridge to lung transplant with ECMO for right heart failure
This study tests a special heart-lung support machine (ECMO) for people waiting for a lung transplant whose heart is failing due to high blood pressure in the lungs. The machine helps rest the heart and lungs until transplant surgery.
Jacksonville, FloridaAges 18–80 - NCT06771518RecruitingPhase 2
Study combining chest radiation and immunotherapy for lung cancer
This study tests whether adding radiation to the chest area can improve the effectiveness of maintenance immunotherapy (atezolizumab) in patients with extensive-stage small cell lung cancer who have responded well to initial treatment.
Rome, RomeAges 18 years+ - NCT06765135Enrolling by invitation
Respiratory test for smarter antibiotic use
This trial tests a quick, point-of-care test for respiratory infections in primary care. The goal is to help doctors decide when antibiotics are needed, reducing unnecessary use.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06768307RecruitingPhase 2
Adebrelimab + Chemo with Radiation for Extensive-Stage SCLC
This study tests whether giving a combination of the immunotherapy drug Adebrelimab plus chemotherapy together with radiation (given at the same time) is better than giving radiation after chemo for people with extensive-stage small cell lung cancer who haven't been treated before.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06761170RecruitingPhase 2
Spray Freezing for Non-Cancerous Airway Narrowing
This trial is testing a treatment called spray cryotherapy, which uses extreme cold to open up a narrowed airway. It may help people with non-cancerous (benign) narrowing of the windpipe or voice box area that is causing symptoms like trouble breathing.
Boston, MassachusettsAges Any age - NCT06770179Enrolling by invitation
Lung breathing maneuver for kids during surgery
This study tests a special breathing maneuver (ultrasound-guided lung recruitment) during surgery to see if it helps prevent small areas of lung collapse in children. It may help kids with longer surgeries keep their lungs open and working better afterward.
IstanbulAges 1–14 - NCT04281979Recruiting
Testing a substance’s effects in adult cigarette and vape users
This study tests how a specific substance affects people who currently smoke cigarettes or e-cigarettes. You may be able to join if you’re within a certain age range and recently had specific smoking and drinking patterns, and if you meet health/safety requirements for study procedures like MRI.
Portland, OregonAges 21–40 - NCT05894070Recruiting
Using your voice recordings to spot cancer coming back
This study looks at whether changes in your voice can help detect early return of laryngeal or hypopharyngeal cancer. If you’ve finished curative treatment and are disease-free for a certain period, your voice will be monitored to see if it can signal recurrence sooner.
BernAges 18 years+ - NCT06755814Recruiting
Registry for pneumonia in patients with weakened immune systems
This registry study collects information from patients hospitalized with pneumonia who also have a weakened immune system. The goal is to better understand how to treat and manage pneumonia in people like you.
Milan, MilanoAges 18 years+ - NCT06752395Enrolling by invitation
Freezing vs. forceps biopsy for small lung nodules
This trial compares two ways of taking a tissue sample from a small lung nodule: traditional forceps (like tiny tweezers) versus a newer freezing method (cryobiopsy). It will help find out which technique is better at getting enough tissue for diagnosis with fewer side effects.
BusanAges 18 years+ - NCT06758791Enrolling by invitation
Breathing, balance, and walking after stroke
This study looks at how breathing muscle function relates to balance and walking in people who have had a stroke. It may help find new ways to improve recovery.
Istanbul, BüyükçekmeceAges 18–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.