Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06749691RecruitingPhase 2
Liposomal irinotecan and apatinib for extensive-stage small cell lung cancer
This trial tests a combination of two drugs, liposomal irinotecan and apatinib, for people with extensive-stage small cell lung cancer (ES-SCLC) that has progressed after first or second line treatment. The goal is to see if this new combination can help shrink tumors or slow the cancer's growth.
Hangzhou, ZhejiangAges 18–75 - NCT06749860RecruitingPhase 2
Targeted drug combo for HER2-positive advanced lung cancer
This trial tests a combination of three drugs (Disitamab Vedotin, Tislelizumab, and Bevacizumab) for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene or protein. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT06749886RecruitingPhase 2
Tislelizumab plus chemo for advanced lung cancer after prior immunotherapy
This trial tests a drug called Tislelizumab (an immunotherapy) combined with chemotherapy for people with advanced NSCLC who have already been helped by a different immunotherapy. It's a second-line option for those who did well on their first immunotherapy but now need another treatment.
ShanghaiAges 18 years+ - NCT06750289RecruitingPhase 3
Testing benralizumab for uncontrolled eosinophilic asthma
This study tests if adding a new injectable medicine (benralizumab) to your current medium-dose inhaler works better than simply increasing your inhaler dose to control hard-to-treat asthma. It may help people with a specific type of asthma linked to high eosinophil levels.
Chandler, ArizonaAges 12–75 - NCT06750536Recruiting
Safety study of a new lung support device for small children
This trial is testing a new device (MiniLung Petite Kit) for babies and young children with severe lung or heart failure. The device helps oxygenate the blood and remove carbon dioxide, giving the lungs and heart a chance to rest and heal.
Bonn, North Rhine-WestphaliaAges Up to 8 months - NCT06751069Recruiting
Home exercise and coaching for lung scarring
This study tests a home-based exercise and health coaching program for people with scarring in their lungs (fibrotic ILD). The goal is to see if doing rehab at home, with support from a coach, can help you feel better and breathe easier.
Scottsdale, ArizonaAges 18 years+ - NCT06751082Recruiting
Sotatercept for pulmonary hypertension study
This study looks at how well the drug Sotatercept works for people with pulmonary hypertension (high blood pressure in the lungs) in a real-world clinic setting. If you are already taking Sotatercept, you may be able to join.
Rochester, MinnesotaAges 18 years+ - NCT06751537Recruiting
Testing a wearable device for COPD severity
This trial tests a wearable device (WearME) that tracks your breathing and activity to see how well it can measure COPD severity. It may help you and your doctor better understand your lung function at home.
Baltimore, MarylandAges 21–100 - NCT06752122RecruitingPhase 1
Safety study of RCS-21 in healthy volunteers
This study is testing a new inhaled drug called RCS-21 in healthy volunteers to see if it's safe and how the body handles it. You will be closely monitored and may receive either the drug or a placebo.
HanoverAges 18–64 - NCT06752720RecruitingPhase 2
Stem cell therapy for chronic stroke patients
This trial tests whether a patient's own stem cells can be safely injected into the brain to help recovery after a stroke. It is for people who had an ischemic stroke 6 months to 5 years ago and still have moderate to severe symptoms.
Sapporo, HokkaidoAges 20–70 - NCT06753214Recruiting
Telemedicine training for caregivers to improve child asthma control
This trial tests if teaching caregivers about asthma care through telemedicine can help children with uncontrolled asthma feel better. It is designed for children whose asthma is not well-controlled and who are already being treated at a hospital clinic.
Can ThoAges 4–16 - NCT06753474RecruitingPhase 1
Flu challenge study for healthy adults
This study tests how healthy adults respond to being exposed to a flu virus in a controlled setting. You will be closely monitored and may help researchers learn more about flu and potential treatments.
Atlanta, GeorgiaAges 18–49 - NCT06753786Recruiting
Blood thinner timing study for bleeding stroke patients
This study looks at when it is safest to start blood thinners to prevent blood clots (deep vein thrombosis) after a type of bleeding stroke called hypertensive intracerebral hemorrhage. Researchers want to find the best time to start this prevention treatment.
MoscowAges 18 years+ - NCT06753981Recruiting
Triple drug therapy for new PAH patients
This trial tests whether a combination of three medications works well and is safe for people newly diagnosed with pulmonary arterial hypertension (PAH) that is not low-risk. It aims to see if starting with triple therapy early can improve outcomes.
Jinan, ShandongAges 18–80 - NCT06754930RecruitingPhase 1/Phase 2
Study of SHR-1826 combined with other treatments for lung cancer
This trial tests a new drug called SHR-1826 in combination with other anti-cancer therapies for people with non-small cell lung cancer (NSCLC). It aims to see if these combinations are safe and effective for patients who haven't been treated before or whose cancer has come back.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06755008Recruiting
Cell repair for lung health in COPD
This study tests whether special stem cells can help repair lung damage in people with COPD. It may help us understand how to improve lung function for those who smoke or have smoked.
Montpellier, HéraultAges 18 years+ - NCT06755684RecruitingPhase 2
Pre-surgery targeted drug combo for EGFR-mutant lung cancer
This trial tests a new targeted pill (befotertinib) given before surgery, either with another targeted drug (bevacizumab) or with standard chemotherapy. The goal is to shrink the tumor and improve outcomes for people with a specific type of lung cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06755814Recruiting
Registry for pneumonia in patients with weakened immune systems
This registry study collects information from patients hospitalized with pneumonia who also have a weakened immune system. The goal is to better understand how to treat and manage pneumonia in people like you.
Milan, MilanoAges 18 years+ - NCT06755840Recruiting
Sleep breathing problems and multiple health conditions study
This study is for people who may have sleep-related breathing problems (like sleep apnea). It looks at how these issues connect with other health conditions. Participants will do a one-night sleep test and some simple health checks at Xiangya Hospital.
ChangshaAges Any age - NCT06756035RecruitingPhase 1
Testing CT-95 in advanced cancers with mesothelin
This trial tests a new drug (CT-95) for advanced cancers that have a marker called mesothelin. It's an early-phase study to see if the drug is safe and effective.
Denver, ColoradoAges 18 years+ - NCT06756217Recruiting
PET scan to check early response to immunotherapy before lung cancer surgery
This trial tests a special PET scan (68Ga-grazytracer) to see if it can predict early whether immunotherapy is working in people with lung cancer that can be surgically removed. If successful, this scan could help doctors tailor treatment sooner.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06756230Recruiting
Downhill walking exercise for IPF patients
This study tests whether downhill walking improves lung function and exercise ability in people with idiopathic pulmonary fibrosis (IPF). If you can walk on a treadmill and haven't been in a structured exercise program recently, you may qualify.
Istanbul, ÜsküdarAges 18–75 - NCT06756633Recruiting
Breathing and movement study for neuromuscular disease
This study looks at breathing, chest and belly movement, and exercise ability in people with Duchenne Muscular Dystrophy or Spinal Muscular Atrophy, as well as healthy people. The goal is to compare these functions to help understand how these diseases affect the body.
Ankara, ÇankayaAges 5–15 - NCT06756646Recruiting
Aerobic exercise and BFRT for COPD patients
This trial tests if adding a special band (BFRT) to walking or biking can help people with COPD breathe better and get stronger. It may be a good option if you have moderate to very severe COPD and haven't been in a rehab program lately.
Tainan, TaiwanAges 30–85
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.