Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,622 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2849
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD144
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California389
- Alabama175
- Arizona154
- Massachusetts128
- Florida119
- New York113
- Maryland111
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,622 total
- NCT07284602RecruitingPhase 3
Comparing a new drug to pirfenidone for lung scarring
This trial tests a new medicine, LYT-100 (deupirfenidone), against the standard drug pirfenidone for people with idiopathic pulmonary fibrosis (IPF). It aims to see if the new drug works better or has fewer side effects.
Palm Spring, CaliforniaAges 40 years+ - NCT07322341RecruitingPhase 2
Study of SX-682 with atezolizumab for advanced lung cancer
This trial tests a new drug combination (SX-682 plus atezolizumab) for people with advanced non-small cell lung cancer that has grown after standard treatments like immunotherapy and chemotherapy. It aims to see if the combination can help shrink or slow the cancer.
Seattle, WashingtonAges 18 years+ - NCT07195734RecruitingPhase 2
Adding chemo or immunotherapy before surgery for advanced head and neck cancer
This trial tests whether giving chemotherapy or chemotherapy plus immunotherapy before surgery can improve outcomes for people with advanced head and neck cancer that has come back or not gone away after prior treatment.
Tucson, ArizonaAges 18 years+ - NCT07305207RecruitingPhase 1
Influenza H3N2 infection study for pandemic preparedness
This study gives healthy adults a controlled dose of influenza H3N2 virus to learn how the body responds. The goal is to build a model that can help develop better vaccines and treatments for future flu pandemics.
Halifax, Nova ScotiaAges 18–45 - NCT05150691RecruitingPhase 1/Phase 2
Early study of an HER2 drug in advanced solid tumors
This early-phase trial tests DB-1303 and BNT323 together in people with advanced or metastatic solid cancers that have specific HER2 features. It may be an option when standard treatments have stopped working, aiming to find a safer dose and early signs of effectiveness.
Cerritos, CaliforniaAges 18 years+ - NCT07127926RecruitingPhase 1
Belumosudil pill vs crushed pill study for chronic GVHD
This trial tests whether crushing belumosudil tablets changes how the drug works in people with chronic graft-versus-host-disease (GVHD), a complication after a stem cell transplant. It helps doctors know if taking crushed pills is as effective as whole tablets.
Houston, TexasAges 18 years+ - NCT07543939Recruiting
Breathing measurements during minimally invasive abdominal surgery
This study measures how your lungs respond to a specific breathing machine setting during planned abdominal surgery. Understanding these measurements may help doctors use ventilation (breathing assistance) more safely during surgery.
RiyadhAges 18–65 - NCT07705737RecruitingPhase 2
Testing Rademikibart for asthma or COPD flare-ups
This trial tests an investigational drug called Rademikibart for people having a severe asthma or COPD flare-up that needs emergency care and steroids. The study aims to see if the drug can help control the flare-up faster and reduce the need for more treatment.
Miami, FloridaAges 18–85 - NCT06687369RecruitingPhase 3
Comparing a potential biosimilar to Keytruda for advanced lung cancer
This trial tests if a new drug, MB12, works as well as Keytruda for people with advanced non-small cell lung cancer who haven't had treatment yet. It aims to offer a more affordable option.
YerevanAges 18 years+ - NCT07660055RecruitingPhase 1
Radioactive drug for advanced solid tumors
This trial tests a new radioactive drug (called 177Lu-DWJ155) that targets and kills cancer cells, along with a similar imaging agent (68Ga-DWJ155) used to see where the drug goes in the body. It is for people with certain advanced solid tumors that have not responded to standard therapies.
Omaha, NebraskaAges 18 years+ - NCT07025421Recruiting
Using vertical positioning for ARDS patients
This study tests whether raising the head of the bed (vertical positioning) can help patients with ARDS breathe better. It may offer a simple, non-drug way to improve oxygen levels.
Birmingham, AlabamaAges 18–80 - NCT07447284Recruiting
Improving sleep for African American couples with OSA
This study tests whether a couple-based approach helps African American patients with moderate to severe sleep apnea stick with CPAP therapy better. It is designed for patients and their bed partners who want to improve sleep health together.
Cleveland, OhioAges 30 years+ - NCT06726720Recruiting
Real-world study of approved lung cancer drugs
This study looks at how well approved AstraZeneca drugs work for non-small cell lung cancer in everyday medical practice. It does not test new treatments, but gathers information to help doctors and patients make better decisions.
Aix-en-ProvenceAges 18 years+ - NCT07630961RecruitingPhase 1
New PET Imaging Scans for Advanced Solid Tumors
This trial tests two new radioactive imaging scans (called PET scans) designed to better detect certain advanced cancers like pancreatic, lung, breast, colon, or soft-tissue tumors. The goal is to see if these scans help doctors find and track cancer more accurately than standard imaging.
Odense CAges 18 years+ - NCT06442930Recruiting
Extubation study: watching breathing tube removal
This study watches how patients do after a breathing tube is removed (extubation) in the operating room, ICU, or other anesthesia areas. It aims to learn about complications and improve care.
Tucson, ArizonaAges 18 years+ - NCT07468071RecruitingPhase 1/Phase 2
Continuing opnurasib treatment for patients who are benefiting
This trial allows people who are already taking opnurasib in another Novartis study and seeing good results to keep receiving it. The goal is to let them continue treatment without interruption.
Sint-Niklaas, Oost VlaanderenAges 18–100 - NCT07525375RecruitingPhase 2
Lung Function Study of Inhaled Glycopyrronium With BFF in Children With Asthma
This study tests whether adding a medication called glycopyrronium to a common asthma inhaler (BFF) helps children ages 4–12 breathe better. Researchers will measure lung function and compare two different doses of the added medication.
Bakersfield, CaliforniaAges 4–11 - NCT06596655Recruiting
Single-use bronchoscopes for lung procedures
This study is testing a single-use (disposable) bronchoscope for lung procedures like biopsies. It aims to see if it's safe and effective for patients who need a lung procedure.
Boston, MassachusettsAges 18 years+ - NCT06881784RecruitingPhase 3
Study of a RAS-targeting pill for lung cancer
This trial tests a new daily pill (daraxonrasib/RMC-6236) for people with advanced non-small cell lung cancer that has a specific RAS mutation. It's for those who have already tried 1 or 2 previous treatments, including immunotherapy and chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT07725939RecruitingPhase 2
Study of Galvokimig for moderate-to-severe COPD with chronic bronchitis
This study tests an experimental drug called Galvokimig (taken as a pill) to see if it can reduce COPD flare-ups and improve lung function in people with moderate to severe COPD and chronic bronchitis. It is for those who have had recent flare-ups and are already using maintenance inhalers.
Columbus, OhioAges 40–80 - NCT07117214RecruitingPhase 1
Study of a new imaging agent for breast and lung cancers
This trial tests a new imaging agent called [68Ga]Ga-DWJ155 to see how well it helps detect certain types of advanced breast cancer and non-small cell lung cancer. It may help doctors better understand the cancer and guide treatment decisions.
Groningen, Provincie GroningenAges 18–100 - NCT06727578Recruiting
Pleural irrigation with a new device
This trial tests a new device to wash out fluid that stays in the chest after a chest tube is placed. It might help people who cannot receive standard medication to break up this fluid within the first day after their chest tube is inserted.
Boston, MassachusettsAges 18 years+ - NCT07154927Recruiting
Using ultrasound to guide heart catheterization for pulmonary hypertension
This trial tests if using ultrasound to guide a catheter into the lung's blood vessels is a good way to diagnose pulmonary hypertension. It may help find a safer, more accurate method for diagnosis.
Asyut, Select A StateAges Any age - NCT06482073Recruiting
Genetic testing for suspected lung cancer
This study looks at genetic changes in people with suspected or high-risk lung cancer. It aims to use those results to guide more personalized treatment decisions.
Rochester, MinnesotaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,622 recruiting pulmonology studies from the U.S. registry right now, out of 10,481 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.