Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,290
- Phase 2848
- Phase 1471
- Phase 3423
- Phase 1/Phase 2311
- Phase 4207
- Phase 2/Phase 368
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer170
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome73
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca64
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Chinese University of Hong Kong35
- Riphah International University34
Where studies are running
- California390
- Alabama175
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06967805RecruitingPhase 2
Study of MTX-463 for Idiopathic Pulmonary Fibrosis
This trial tests an experimental drug called MTX-463 for people with idiopathic pulmonary fibrosis (IPF). It aims to see if targeting a protein called WISP1 can slow lung scarring and help you breathe better.
Birmingham, AlabamaAges 40 years+ - NCT07361497RecruitingPhase 3
New Drug vs Standard Drug After Chemoradiation for Stage 3 Lung Cancer
This study tests a new drug, pumitamig, against an older drug, durvalumab, for people with stage 3 non-small cell lung cancer that cannot be removed by surgery and has not progressed after chemotherapy and radiation. The goal is to see which drug works better to keep the cancer from growing.
Daphne, AlabamaAges 18 years+ - NCT07668752RecruitingPhase 3
New pill (GFH375) vs chemo for KRAS G12D lung cancer
This study tests a new pill (GFH375) against a standard chemotherapy (docetaxel) for advanced lung cancer with a specific KRAS G12D mutation. If you have already tried platinum chemo and an immunotherapy, this trial might offer a new option.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07098988RecruitingPhase 2
Visugromab plus standard chemo-immunotherapy for lung cancer
This trial tests an experimental drug called visugromab added to standard chemotherapy and immunotherapy for people newly diagnosed with advanced non-squamous lung cancer. It aims to see if the combination works better than standard treatment alone.
Birmingham, AlabamaAges 18 years+ - NCT07361510RecruitingPhase 3
Pumitamig vs Keytruda for advanced lung cancer with high PD-L1
This trial compares an experimental drug called Pumitamig with the approved immunotherapy drug Pembrolizumab (Keytruda) as the first treatment for advanced lung cancer that has high PD-L1 levels. The goal is to see which drug works better and has fewer side effects.
Daphne, AlabamaAges 18 years+ - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT07194382RecruitingPhase 2
Testing a new liquid form of nintedanib for IPF
This trial tests a liquid version of the medication nintedanib (AP02) to see if it is safe and works well for people with idiopathic pulmonary fibrosis (IPF). If you have IPF and have not taken nintedanib or pirfenidone recently, you may be able to join.
Camperdown, New South WalesAges 40 years+ - NCT06026111Recruiting
Exercise during immunotherapy for lung cancer
This study tests if adding a structured exercise program can help people with non-small cell lung cancer who are already on immunotherapy. It is for people who are not currently very active and are willing to travel to Dana-Farber Cancer Institute for some visits.
Boston, MassachusettsAges 18 years+ - NCT07590531RecruitingPhase 1/Phase 2
Two-Drug Lung Cancer Treatment Study
This trial tests a combination of two experimental drugs (AMT-116 and ivosidan) for patients with advanced lung cancer that cannot be removed by surgery. The study aims to see if this combination can help shrink tumors and improve survival.
Guangzhou, GuangdongAges 18–75 - NCT06567704Recruiting
Fatigue from immunotherapy in lung cancer: a patient interview study
This study aims to understand how maintenance immunotherapy affects fatigue in people with non-small cell lung cancer. Researchers will talk with patients to learn about their experiences.
Charlotte, North CarolinaAges 18 years+ - NCT07554352Recruiting
Home Device to Detect COPD Flare-Ups Early
This study tests a home monitoring device designed to catch COPD flare-ups (exacerbations) before they become severe. If you have had recent flare-ups, this device might help you stay healthier by alerting your doctor to problems early.
Omaha, NebraskaAges 21 years+ - NCT07704658RecruitingPhase 4
Pralsetinib drug interaction study for advanced solid tumors
This trial tests how pralsetinib interacts with other drugs in people with advanced solid tumors that have a specific RET gene change. It aims to find the right dose and safety profile.
Logroño, La RiojaAges 18 years+ - NCT06623422RecruitingPhase 3
Vaccine plus Keytruda for lung cancer after surgery
This trial tests combining a cancer vaccine (V940) with the immunotherapy drug pembrolizumab (Keytruda) for people with non-small cell lung cancer that was treated with chemo and Keytruda before surgery but wasn't completely removed. The goal is to see if adding the vaccine helps prevent the cancer from coming back.
Gilbert, ArizonaAges 18 years+ - NCT02800499Enrolling by invitation
COPD subgroup registry for people with cough and shortness of breath
This study enrolls certain people with chronic obstructive pulmonary disease (COPD) to better understand COPD “subtypes” and symptoms like cough, mucus (sputum), and shortness of breath. It may help researchers predict what kind of COPD you have and improve future care.
Seoul, SeoulAges 40 years+ - NCT06940856Recruiting
Chloride imbalance in preterm babies
This study looks at chloride levels in preterm babies admitted to the neonatal intensive care unit (NICU) within their first day of life. It aims to understand chloride imbalance and how it might affect their health.
Istanbul, TurkeyAges 1 hour–1 month - NCT06915441RecruitingPhase 2
Lipid infusions to improve nutrition for premature babies
This trial tests whether giving fat (lipid) infusions can improve nutrition and growth in very premature or very low birth weight babies. It may be for babies born before 28 weeks or weighing 1,000 grams or less.
Houston, TexasAges 12 hours–6 months - NCT06776783RecruitingPhase 3
Testing a new surfactant for breathing problems in premature babies
This study tests a new medicine called APC-0101, a type of surfactant, for premature babies with breathing problems (respiratory distress syndrome). It may help their lungs work better and reduce the need for more breathing support.
Little Rock, ArkansasAges 1 hour–1 day - NCT06816706Recruiting
Comparing two oxygen methods during breathing trials
This study compares two ways of giving oxygen (high-flow through the nose vs. a T-piece) to help patients come off a breathing machine safely. It aims to see which method works better during a test of your ability to breathe on your own.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06805214Recruiting
Body temperature after tracheostomy: a study
This study looks at whether body temperature changes after a tracheostomy, a surgery that creates a hole in the neck to help with breathing. The goal is to help doctors better understand what is normal after this procedure.
Kfar SabaAges 18–99 - NCT06784492Recruiting
Healthy living tips after a pulmonary embolism
This study tests whether healthy living tips and messages sent daily by text or email can help you recover better after a serious blood clot in your lung called a pulmonary embolism. It may be a good fit if you are already taking a blood thinner and can receive text messages.
Rochester, New YorkAges 18 years+ - NCT06776900Recruiting
Breathing tube placement: side vs. back in children
This study compares two ways of placing a breathing tube (fiberoptic intubation) in children during surgery: lying on their side versus lying on their back. It aims to see which position is easier and safer for kids having non-head-and-neck surgeries.
CairoAges 2–10 - NCT06759038Recruiting
Comparing two devices for placing a breathing tube in lung surgery
This trial compares a new video laryngoscope to a standard one for placing a special breathing tube used in lung surgeries. It aims to see which device works better for patients having planned chest operations.
Karachi, SindhAges 18–60 - NCT06758791Enrolling by invitation
Breathing, balance, and walking after stroke
This study looks at how breathing muscle function relates to balance and walking in people who have had a stroke. It may help find new ways to improve recovery.
Istanbul, BüyükçekmeceAges 18–80 - NCT06671288Recruiting
Balloon exercises for smokers with mild COPD
This trial tests if blowing up balloons while activating your core muscles can help smokers with mild breathing problems. You would do simple exercises to improve your lung function and breathing.
Rawalpindi, Punjab ProvinceAges 25–59
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,500 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.