Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT07065162Recruiting
Touch and breathing exercises for COPD
This trial tests two techniques—a gentle touch method and a breathing exercise routine—to see which helps people with mild to moderate COPD feel better and breathe easier.
Lahore, Punjab ProvinceAges 45–65 - NCT07065565Recruiting
Tubeless surgery for windpipe and airway reconstruction
This trial tests a surgery to repair the windpipe (trachea) or its branches (carina) without using a breathing tube during the procedure. It may help patients with certain airway diseases who are healthy enough to avoid traditional breathing support during surgery.
Guangdong, GaungzhouAges 18–80 - NCT07065604Recruiting
Tubeless surgery for chest tumor
This trial tests a new way to remove a chest tumor without using a breathing tube or chest tube. If you have a small mediastinal tumor and are in good health, you might be able to have a less invasive surgery.
Guangzhou, GuangdongAges 18–80 - NCT07065799Recruiting
Breathing strategies for COPD with high carbon dioxide
This trial compares different breathing strategies for people with COPD who still have high carbon dioxide levels in their blood a few weeks after a severe flare-up. The goal is to find the best way to help you breathe easier and improve your oxygen levels.
ArezzoAges 18–90 - NCT07066566Recruiting
Comparing two ways to give high flow oxygen through the nose
This trial compares two types of high flow nasal cannula to see which one makes it easier for you to breathe. You may join if you are 18 or older and have normal oxygen levels without extra oxygen.
LarissaAges 18 years+ - NCT07068438Recruiting
Pulsed electric field for chronic bronchitis
This study tests a new treatment that uses brief electric pulses to clear blocked airways in people with chronic bronchitis. It might help if you have a long-term cough with mucus and standard medicines aren't enough.
Hefei, AnuiAges 35–80 - NCT07070011Recruiting
Studying tiny particles in blood to predict treatment response in lung cancer
This trial looks at small particles called extracellular vesicles in your blood to see if they can help predict how well immunotherapy combined with chemotherapy will work for extensive-stage small cell lung cancer. The goal is to find markers that could guide future treatment decisions.
ShanghaiAges 45–80 - NCT07070518RecruitingPhase 1/Phase 2
Study of GV20-0251 for advanced solid tumors
This trial tests a new study drug, GV20-0251, for people with advanced solid tumors that no longer respond to standard therapies. It aims to see if the drug can shrink tumors or slow their growth.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07070895Recruiting
Wellness app for chronic cough study
This trial tests a smartphone app and a smartwatch to help people with chronic cough that hasn't improved with standard care. You'll wear a watch to track your cough and use the app to learn management techniques.
Wilmington, DelawareAges 21 years+ - NCT07071103RecruitingPhase 2
Low-dose radiation and immunotherapy for resistant solid tumors
This trial tests a combination of low-dose radiation to the intestines and immunotherapy for people whose cancer has stopped responding to standard treatments including immunotherapy. It may offer a new option when other therapies have failed.
Shantou, GuangdongAges 18–80 - NCT07071324Recruiting
CF Wellness Program for Fatigue
This wellness program tests if coaching sessions can help people with cystic fibrosis who feel tired. It is a remote program you can join using your phone or computer, as long as you get CF care at a participating center.
Denver, ColoradoAges 18 years+ - NCT07071935RecruitingPhase 2
Early ventilation study for newly diagnosed ALS
This trial tests whether starting non-invasive ventilation (breathing support) early in ALS helps people breathe easier and live better. If you've been diagnosed with ALS in the last 6 months and haven't used a breathing machine before, you may qualify.
Hershey, PennsylvaniaAges 18 years+ - NCT07072039Recruiting
Paramedic home care for COPD flare-ups
This study tests whether a special paramedic program can help people with COPD (a chronic lung disease) avoid future emergency visits by providing in-home care and support. It is for patients with recent COPD flare-ups who are seen at certain clinics in Worcester.
Worcester, MassachusettsAges 18 years+ - NCT07073365RecruitingPhase 2
Adding local therapy after osimertinib plus chemo for EGFR lung cancer
This trial tests whether directly treating the remaining lung tumor with surgery or radiation, after initial chemo and osimertinib, can improve outcomes for people with advanced EGFR-mutant non-small cell lung cancer.
BusanAges 20 years+ - NCT07073638RecruitingPhase 2
Testing a new TB drug called RESP30TB in people with newly diagnosed TB
This trial tests a new drug, RESP30TB, to see if it is safe, tolerable, and can quickly kill TB bacteria in people with newly diagnosed, rifampicin-susceptible pulmonary TB. You may be eligible if you can produce sputum and meet other health criteria.
Cape Town, BellvilleAges 18–65 - NCT07073950RecruitingPhase 4
A study on a triple inhaler for COPD with hyperinflation
This study tests a triple-combination inhaler (budesonide, glycopyrronium, formoterol) against a placebo inhaler to see how it affects your heart and lungs if you have COPD and over-inflated lungs.
AhrensburgAges 40–80 - NCT07074288Recruiting
Sleep apnea treatments for people who can't use CPAP
This study is comparing two alternative treatments for moderate to severe sleep apnea in people who cannot or will not use a CPAP machine. The treatments are a custom-fitted dental device and a nerve stimulation implant, and the study will see how well they work.
St Louis, MissouriAges 18 years+ - NCT07076667Recruiting
Relaxation and Tai Chi for COPD
This study compares two relaxing exercises—Benson's relaxation technique and Tai Chi—to see if they help people with moderate to severe COPD feel better and breathe easier.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 40–50 - NCT07076862RecruitingEarly Phase 1
PET scan study for long COVID symptoms
This study uses a special PET scan to look at inflammation in the body of people with long COVID (symptoms lasting 3+ months after infection). The goal is to understand why symptoms persist and find better ways to help.
Sacramento, CaliforniaAges 18 years+ - NCT07077213Recruiting
PET scan test for TB-related lung scarring
This study uses a special PET scan (called FAPI-74) to see if it can detect fibrosis (scarring) in the lungs of people with active TB. It looks at the scan both at the start of treatment and after 6 months of therapy to understand how the lungs heal.
Cincinnati, OhioAges 18 years+ - NCT07077382Recruiting
Pneumoconiosis and Dust Exposure China Study
This study is building a long-term group of people with pneumoconiosis to better understand the disease and how dust exposure affects health. It does not involve any new treatments or medicines.
Beijing, Beijing MunicipalityAges Any age - NCT07077486RecruitingPhase 4
Testing telitacicept vs cyclophosphamide for lupus lung disease
This trial tests if a new drug called telitacicept works better than a standard lupus medicine (cyclophosphamide) to improve lupus-related lung scarring (interstitial lung disease). It might be an option if your breathing tests are still good enough.
Wuhan, HubeiAges 18–80 - NCT07079150Recruiting
Long-term pegylated interferon study for HBV families with poor outcomes
This study looks at how well pegylated interferon alpha-2b works over the long term for people with chronic hepatitis B who come from families where the virus has caused serious liver problems like cirrhosis or liver cancer. The goal is to see if this treatment can help prevent these bad outcomes in family members.
Xi'an, ShaanxiAges 18–70 - NCT07079553Recruiting
Diaphragm stimulation with breathing exercises for COPD
This study tests whether a gentle electrical stimulation on your diaphragm (the muscle that helps you breathe) combined with deep breathing exercises can improve your breathing and quality of life. It is for people with mild to moderate COPD who do not smoke and have a chronic cough with mucus.
Lahore, Punjab ProvinceAges 40–60
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.