Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05664204Recruiting
ECMO before or after lung transplant to improve outcomes
This study looks at using a heart–lung machine (ECMO) to reduce complications and deaths after a lung transplant. It focuses on people getting a lung transplant who have certain types of lung-vessel (pulmonary) pressure problems.
ParisAges 18 years+ - NCT05789953Recruiting
Machine-learning plan to prevent lung complications after surgery
This trial tests a computer-based (machine-learning) approach to help prevent lung problems after elective surgery done under general anesthesia. It may help by identifying higher-risk patients and guiding care to reduce postoperative pulmonary complications.
UlmAges 18 years+ - NCT05836103Recruiting
Texting on your phone to help you quit smoking
This trial tests whether smartphone texting messages can help young adults stop smoking. If you’re planning to quit soon, the messages may support you during the quitting process.
Baltimore, MarylandAges 18–30 - NCT05815199Recruiting
E-cigarettes to help smokers with serious mental illness cut down
This study tests whether e-cigarettes can help people who smoke a lot reduce cigarette use (without requiring them to quit completely). It is designed for adults with serious mental illness and focuses on harm reduction and follow-up over time.
New York, New YorkAges 21 years+ - NCT05843500Recruiting
CTEPD and CTEPH registry for long-term blood-clot lung disease
This study builds a registry to learn about people with chronic blood-clot lung disease (CTEPD/CTEPH) and what symptoms and test results look like over time. It may help clinicians better understand the condition and improve future care, since your participation supports data collection rather than a new drug.
San Francisco, CaliforniaAges 18 years+ - NCT05881863Recruiting
Oxygen monitoring during rigid bronchoscopy with special ventilation
This study checks oxygen levels in the airway while doctors perform rigid bronchoscopy for a blockage in the center of the lungs using a specific ventilation method. It may help teams improve safety and control oxygen during this procedure.
Minneapolis, MinnesotaAges 18 years+ - NCT05587751Recruiting
Testing how gender-affirming care affects lung function
This study checks whether gender-affirming treatments change breathing/lung test results over time. It may help doctors understand any lung-related effects for transgender and gender-diverse people.
Rochester, MinnesotaAges 14 years+ - NCT05660525Recruiting
Helping rural smokers quit with pharmacist support and nicotine replacement
This study tests a smoking-cessation program delivered through community pharmacies in rural Appalachia. It may help people quit smoking using nicotine replacement (patch or lozenges) plus support from pharmacists.
Charlottesville, VirginiaAges 18 years+ - NCT05526534Recruiting
Breathing treatment to prevent lung problems after gynecologic surgery
This trial studies whether a breathing support therapy given after surgery can reduce the chance of lung complications. It focuses on people having gynecologic tumor surgery who are at higher risk for breathing or lung problems.
Chengdu, SichuanAges 18–90 - NCT05298982Enrolling by invitation
Join a long-term follow-up study for ICU care
This study follows people who joined the TEAM Phase III trial to learn how ICU care affects health over the long term. Your participation helps researchers understand outcomes long after the initial treatment.
Camperdown, New South WalesAges 18 years+ - NCT05578742Recruiting
Test breathing support patterns in moderate to severe ARDS
This trial studies how adjusting ventilator settings can better match the lungs’ ability to move air and oxygen in people with moderate to severe ARDS. It may help doctors tailor breathing support for different “lung mechanics” patterns, especially during the first days after intubation.
Angers, Maine et LoireAges 18 years+ - NCT05415371Enrolling by invitation
Smoking help program for pregnant women in Medicaid
This study tests a smoking-cessation program for pregnant people who smoke while using Medicaid. It may help reduce smoking during pregnancy through structured support calls.
Oklahoma City, OklahomaAges 18–105 - NCT05542069Recruiting
Training with a breathing device measured in healthy adults
This study measures how the diaphragm (main breathing muscle) works while you do breathing training using a special breathing device (IMT). It’s done in healthy adults to better understand how the training affects breathing.
Buenos AiresAges 18 years+ - NCT05426200Recruiting
Health coaching program for people waiting for lung transplant
This study tests whether personalized health coaching can improve how you feel and report your symptoms and wellbeing while you’re waiting for a lung transplant. It may help you better manage your health before transplant.
Jacksonville, FloridaAges 18 years+ - NCT05555069Recruiting
Menthol-flavored vaping study for adult menthol cigarette smokers
This study looks at how menthol flavoring may affect whether adult menthol cigarette smokers switch to e-cigarettes. You may be asked to switch and use e-cigarettes over a set period, while researchers track your smoking behavior.
Kansas City, MissouriAges 21 years+ - NCT05388682Recruiting
Treating Takayasu disease with lung artery involvement
This trial studies treatment for people with Takayasu arteritis when it affects the lung arteries. It may help reduce problems caused by narrowed or involved lung arteries.
BeijingAges Any age - NCT05581745Recruiting
Testing a lung transplant approach for certain blood type O patients
This study looks at lung transplants for people getting their first transplant who are blood type O and have low levels of antibodies that may react to donor tissue. It may help doctors choose the safest donor-recipient match for these patients.
Toronto, OntarioAges 18 years+ - NCT05570552Recruiting
Testing health impacts in adults from smoky, arsenic-exposed homes
This study follows adults who took part in an earlier GEOHEALTH study and live in homes that use traditional stoves, with low-to-moderate arsenic exposure in drinking water. It aims to understand how these environmental factors affect health, and what changes might be possible.
DhakaAges 25–70 - NCT05627674Enrolling by invitation
Help improve lung cancer screening and quitting support uptake
This study tests a “precision” approach to help people who are newly eligible for lung cancer screening actually get screened and start smoking-cessation treatment. If it works, it could make screening and quitting help easier to access and more engaging.
St Louis, MissouriAges 18 years+ - NCT05482568RecruitingPhase 1/Phase 2
Study drug SHR-A1811 with two lung cancer medicines
This early-phase trial tests an injectable cancer drug (SHR-A1811) given with either pyrotinib or another targeted drug (SHR-1316) in people with advanced lung cancer. The goal is to see how safe the combination is and how well it can control the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05336136Recruiting
Custom breathing-mask fit testing for children
This trial studies whether a custom, non-invasive breathing mask works better or is easier for children to use. It’s meant to improve comfort and fit while supporting breathing therapy without invasive procedures.
Edmonton, AlbertaAges 8–12 - NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations
This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.
Beijing, Beijing MunicipalityAges 18–80 - NCT05486455Recruiting
Lung cancer screening CT for eligible former and current smokers
This study looks at how well a chest CT scan can detect lung cancer early in people with a significant smoking history. If you qualify, your CT results may help improve future screening for people like you.
MarseilleAges 50–80 - NCT07167459Enrolling by invitationPhase 2
Personalized radiation for early stage lung cancer
This trial tests a personalized radiation treatment called SBRT for early-stage non-small cell lung cancer that is located in the outer part of the lung and cannot be removed with surgery. The goal is to see if this approach works well for people who cannot have surgery or choose not to.
Tianjin, Tianjin MunicipalityAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.