Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,348 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2836
- Phase 1458
- Phase 3420
- Phase 1/Phase 2310
- Phase 4212
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer183
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California384
- Alabama176
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,348 total
- NCT07787130Recruiting
Testing a supplement for preventing colds
This trial tests whether a daily supplement called Immune X can help prevent colds in healthy adults. If you often get colds and are in good health, you might be able to join.
Dijon, Côte-d'OrAges 18–65 - NCT07784959RecruitingPhase 1
Study of NXP900 with lorlatinib for ALK-positive lung cancer
This study tests a new drug called NXP900 in combination with lorlatinib for people with ALK-positive lung cancer who have already been treated with lorlatinib and tolerated it well. The goal is to see if this combination is safe and effective.
Fairfax, VirginiaAges Any age - NCT07787117Recruiting
Comparing asthma treatments: switching to a combination inhaler vs adding a daily controller
This study compares two ways to treat asthma: switching from a rescue inhaler (albuterol) to a combination inhaler (albuterol plus budesonide), versus adding a daily controller medication (either a low-dose inhaled steroid or a leukotriene modifier) while continuing albuterol. It aims to see which approach works better for people with asthma who currently use only a rescue inhaler.
Wilmington, DelawareAges 18–99 - NCT05566392Recruiting
Studying long-term recovery in children after COVID-19
This study looks at how long “long COVID” affects children over time. It may help doctors better understand what symptoms last and what support could improve recovery.
TaipeiAges 6–18 - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT02498587Recruiting
Study of severe breathing illness over a short period
This study looks at people who recently had fever and cough along with trouble breathing, to better understand severe acute respiratory illness. By joining, you may help researchers identify patterns that could improve recognition and care.
Melbourne, VictoriaAges Any age - NCT03307018Recruiting
Check if bronchoscopy after lung surgery prevents complications
This study looks at whether doing a brief breathing-tube exam (bronchoscopy) after specific lung surgery can lower the chance of lung complications. It may help improve recovery and reduce post-surgery breathing problems.
Poznan, WielkopolskaAges 18–89 - NCT05360914Recruiting
Hospital care at home for older adults with acute illnesses
This trial tests whether it is safe and helpful to manage certain sudden (acute) infections and medical problems with hospital-level care delivered at home or in a nursing home. It may help you avoid unnecessary hospital stays while still getting close medical follow-up.
SilkeborgAges 65 years+ - NCT06552013Recruiting
Asthma study for kids in Georgetown and South Park
This study tests whether reducing air pollution can help control asthma in children living in the Duwamish Valley. Kids with poorly controlled asthma who live in specified Seattle neighborhoods may benefit from cleaner air.
Seattle, WashingtonAges 6–17 - NCT06115018Recruiting
Oral device for sleep apnea after palate surgery
This study tests whether a special oral device (OPR) can help people with sleep apnea after they have had palate surgery. It looks at how well it works and if the benefits last over time.
TainanAges 18–100 - NCT07778316RecruitingPhase 3
Tarlatamab for small cell lung cancer after first chemotherapy
This trial tests a new drug called tarlatamab, given either as an injection under the skin or through an IV, for people with extensive-stage small cell lung cancer that has grown or come back after one round of chemotherapy. The goal is to see which way of giving the drug works better and is safer.
Orlando, FloridaAges 18–99 - NCT07782957RecruitingPhase 3
New shot for severe nasal polyps with ongoing sinus symptoms
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
Sherman Oaks, CaliforniaAges 18 years+ - NCT07780656RecruitingPhase 3
Felcorekibart for chronic obstructive pulmonary disease (COPD)
This study tests a new medicine, felcorekibart, to see if it can reduce COPD flare-ups better than a placebo after 52 weeks. It's designed for people with high eosinophils, a type of white blood cell linked to inflammation.
Miami, FloridaAges 40–80 - NCT07777822RecruitingPhase 3
First-line treatment for metastatic non-squamous lung cancer with RAS mutation
This trial tests whether adding a new drug (zoldonrasib) to standard chemotherapy and immunotherapy can help people with a specific type of lung cancer. It is for those with a RAS G12D mutation and no prior treatment for metastatic disease.
Plantation, FloridaAges 18 years+ - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT07780643RecruitingPhase 3
Asthma study for uncontrolled asthma on inhaled steroids
This study is testing an investigational medication for people with uncontrolled asthma. Participants must have moderate-to-severe asthma, be on appropriate maintenance therapy, and meet specific safety criteria.
Miami Lakes, FloridaAges 12–80 - NCT07780669RecruitingPhase 3
Study of a new drug for moderate to severe COPD in smokers
This study tests a new medication (GSK5784283) for people with moderate to severe COPD who have a certain type of inflammation (eosinophilic). Participants must be on standard inhaler therapy and have a history of smoking. The trial will compare the new drug to a placebo.
Doral, FloridaAges 40–80 - NCT07782996RecruitingPhase 3
Study of a new asthma drug for people with uncontrolled asthma
This study is testing whether an investigational drug called GSK5784283 can improve asthma control compared to a placebo. It is for people with uncontrolled asthma who are already on standard daily asthma medications.
Miami Lakes, FloridaAges 12–80 - NCT07779408RecruitingPhase 1/Phase 2
H5N8 flu vaccine study for healthy adults
This study tests an experimental flu vaccine designed to protect against the H5N8 bird flu virus. It is given with an ingredient that may boost the immune response. The study will check if the vaccine is safe and how well it triggers the body's defenses.
Tempe, ArizonaAges 18 years+ - NCT07782970RecruitingPhase 3
Treatment for chronic sinusitis with nasal polyps
This study tests a new medication (felcorekibart) to see if it reduces nasal polyps and symptoms like congestion and loss of smell. It may help people whose current treatments aren't enough.
Los Angeles, CaliforniaAges 18 years+ - NCT06551337RecruitingPhase 4
Vitamin D for bronchiectasis patients
This trial tests if taking vitamin D can help people with bronchiectasis have fewer flare-ups. It is only for patients who were in an earlier study that checked their vitamin D levels.
Hong KongAges 18 years+ - NCT07782164Recruiting
Irreversible electroporation for recurrent pelvic tumors
This study tests a new technique called irreversible electroporation (IRE) for treating pelvic tumors that have returned despite earlier treatment. IRE uses electrical pulses to destroy cancer cells without surgery, offering a potential option when other local treatments like surgery or radiation are not suitable.
Amsterdam, North HollandAges 18 years+ - NCT07782879Recruiting
Quit smoking help for menthol cigarette smokers
This study tests different quit-smoking messages to see which ones help people who smoke menthol cigarettes try to quit. You'll look at messages on a computer that tracks your eye movements, and we'll follow up to see if you make a quit attempt.
Santa Barbara, CaliforniaAges 21 years+ - NCT07783477RecruitingPhase 1
Armored CAR T cells for DLL3 positive cancers
This trial tests an experimental treatment using your own immune cells, modified to better find and attack cancer cells that carry a marker called DLL3. It is for people with certain neuroendocrine tumors, including small cell lung cancer, who have already tried standard treatments.
Basking Ridge, New JerseyAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,348 recruiting pulmonology studies from the U.S. registry right now, out of 9,933 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.