Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06120803RecruitingPhase 2
Esomeprazole for preventing radiation-induced esophagitis
This study tests whether a common heartburn medicine (esomeprazole) can help prevent or reduce painful swallowing caused by radiation for lung cancer. If you have stage 3 non-small cell lung cancer and are getting chemo and chest radiation, you may be able to join.
Chicago, IllinoisAges 18 years+ - NCT06083363Recruiting
Recovery after severe lung infection
This study follows patients who had severe pneumonia or acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU) to understand how they recover over time. It aims to identify factors that affect recovery trajectories.
Tortosa, TarragonaAges 18 years+ - NCT06081881Recruiting
High blood pressure in lungs after a severe blood clot
This study monitors people who had a severe lung blood clot to see if they develop high blood pressure in the lungs over time. It aims to catch the condition early, so treatment can start sooner.
AsyutAges 18–80 - NCT06092086RecruitingPhase 2
Lorlatinib for first-line treatment of ALK-positive lung cancer
This trial tests a targeted pill, lorlatinib, for people with advanced ALK-positive non-small cell lung cancer (NSCLC) who have not received previous treatment for advanced disease. It aims to see how well the drug works in this setting.
Guangzhou, GuangdongAges 18 years+ - NCT06025500Recruiting
Muscle function before and after lung valve treatment
This study looks at how well your leg muscles work before and after getting special valves placed in your lungs. It uses an exercise bike test and an MRI scan to measure muscle changes, and the results may help people with COPD breathe better.
GroningenAges Any age - NCT06110962Recruiting
Testing a sleep monitor for heart rate and breathing
This trial is testing an under-mattress device called Sleeptracker-AI to see how well it measures heart rate, breathing, and sleep patterns. It may help people with suspected sleep apnoea get easier sleep monitoring at home.
Macquarie Park, New South WalesAges 20–90 - NCT06121505RecruitingPhase 2
Low-dose radiation plus immunotherapy for advanced lung cancer
This trial tests whether adding low-dose radiation and a type of targeted radiation (SBRT) to a combination of immunotherapy (sintilimab) and chemotherapy works better than immunotherapy and chemotherapy alone for people with advanced squamous cell lung cancer.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT05924113Recruiting
Latin dance program after lung transplant
This trial tests whether learning and doing Latin dance is safe and helpful for people after a lung transplant. It looks at your ability to move, your recovery, and how you feel day to day with a supervised exercise approach.
Jacksonville, FloridaAges 18–80 - NCT06127589Recruiting
Quit for Kids: help parents quit smoking and protect children
This study offers a program to help parents who smoke quit for good, while protecting their young children from secondhand smoke. It uses text messaging and support to make quitting easier.
Hong KongAges 18 years+ - NCT05950724Enrolling by invitationEarly Phase 1
TNF blocker to protect lungs after transplant
This early-stage trial tests whether blocking a specific inflammation signal (TNF-alpha) can help prevent or improve kidney problems and early graft (new lung) dysfunction after a lung transplant at Northwestern. You might be eligible if you’re scheduled for that transplant and are willing to go through study consent and follow-up.
Chicago, IllinoisAges 18 years+ - NCT06125041RecruitingPhase 2
Adebelizumab with chemo and radiation for advanced lung cancer
This trial tests a new drug called Adebelizumab (an immunotherapy) combined with chemotherapy and radiation for people with extensive stage small cell lung cancer. The goal is to see if this combination helps shrink tumors and improves survival.
Jinan, ShandongAges 18–75 - NCT05718323RecruitingPhase 2
Niraparib with immunotherapy maintenance for advanced small-cell lung cancer
This trial tests whether adding niraparib (a pill cancer medicine) to ongoing immunotherapy maintenance can help people with advanced small-cell lung cancer live longer or better. It is for tumors that show a specific protein marker (SLFN11) and that did not worsen after standard first-line chemo-immunotherapy.
AngersAges 18 years+ - NCT06091098Recruiting
Trial for sleep apnea treatments that affect breathing drive
This trial tests whether a gas mixture that slightly changes your breathing can help treat sleep apnea. It may help people whose apnea is linked to low breathing drive during sleep.
Boston, MassachusettsAges 21–80 - NCT05837663Recruiting
Study using blood tests to better assess lung cancer
This study looks at whether a specialized blood test can help doctors better assess lung cancer. It may be helpful if you are an adult who can safely participate and provide a sample for testing.
Phoenix, ArizonaAges 18 years+ - NCT05670093Recruiting
Testing pressure support to ease breathing muscle work
This trial looks at a breathing-support setting that may reduce the effort of your breathing muscles while you’re coming off a ventilator. It’s meant for people who have been on a breathing machine for more than 24 hours during the “weaning” phase.
SolnaAges 18 years+ - NCT05825014Recruiting
Using computer prediction to reduce COPD complications
This study uses information from past hospital discharge records and breathing test results to predict who with COPD may have worse health outcomes later. It may help future COPD care by identifying higher-risk patients earlier.
Hong Kong, New TerritoriesAges 40 years+ - NCT05897125Enrolling by invitation
Telehealth education to help people with COPD after a hospital stay
This study tests whether a telehealth (video/phone) education program can help people with COPD better manage their health after a hospital flare-up. It may reduce the chance of needing to return to the hospital soon after discharge.
Chicago, IllinoisAges 18 years+ - NCT05814510Recruiting
Help deliver an asthma program in schools and homes
This study tests an asthma education and management program for children, involving caregivers at home and staff at participating schools. You may be able to help by taking part in the program and supporting asthma care at home or school.
Baltimore, MarylandAges Any age - NCT05703672RecruitingPhase 3
Switching smokers to e-cigarettes who do not want to quit
This study tests whether switching from regular cigarettes to e-cigarettes helps smokers who are not interested in quitting. You would also be offered varenicline and regular check-ins to compare outcomes over time.
Kansas City, MissouriAges 21 years+ - NCT05906316Recruiting
Study of new treatment plan for MAC lung infection
This study follows people with a newly diagnosed MAC lung infection (a specific type of mycobacterial disease) and tests how they do on the standard three-drug treatment plan. It may help researchers better understand outcomes and safety for this condition.
Portland, OregonAges 18 years+ - NCT05865782Recruiting
Green schoolyard changes to help kids move more
This study looks at whether rebuilding schoolyards with more greenery can increase physical activity for children. It also aims to help with climate-related goals by changing the school environment.
StockholmAges 8–13 - NCT05777603RecruitingPhase 1
Aerosol antibiotics plus pembrolizumab for advanced lung cancer
This trial studies whether inhaled (aerosol) antibiotics combined with pembrolizumab can help people with advanced non-small cell lung cancer that has grown despite standard first treatment. It aims to improve cancer control by testing this new combination in Phase 1 safety and early effectiveness.
Bethesda, MarylandAges 18–120 - NCT05896033Recruiting
Study how menthol cigarette rules affect current menthol smokers
This study looks at how changes in menthol cigarette and e-cigarette rules may affect people who currently smoke menthol cigarettes. You may be asked to complete phone-based reports (like a diary) about your smoking patterns.
Charleston, South CarolinaAges 21 years+ - NCT05710432Recruiting
Exercises to help breathing during ventilator weaning
This study tests whether specific neck and breathing muscle exercises during ventilator weaning can help people breathe more effectively and safely come off the ventilator. It may help patients who have already had trouble with prior weaning attempts.
Toronto, OntarioAges 16 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.