Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,348 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2836
- Phase 1458
- Phase 3420
- Phase 1/Phase 2310
- Phase 4212
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer183
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California384
- Alabama176
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,348 total
- NCT07761351RecruitingPhase 4
Robotic-assisted vs CT-guided lung biopsy comparison
This study compares two ways to biopsy small lung nodules: a robot-assisted scope through the airways or a needle guided by CT scan. If you have a small lung nodule (2 cm or less) that needs testing, participation may help determine which approach is better.
HeidelbergAges 18 years+ - NCT07764237RecruitingPhase 1
mRNA vaccine for older adults to prevent RSV and hMPV
This trial tests a new mRNA vaccine designed to protect older adults against two common respiratory viruses, RSV and hMPV. It aims to see if the vaccine is safe and creates a good immune response.
Québec, QuebecAges 60 years+ - NCT07759245RecruitingPhase 2
Brenipatide for moderate-to-severe COPD
This trial tests a new medicine called Brenipatide to see if it can help people with moderate-to-severe COPD who still have symptoms despite using standard inhalers. The study will compare the effects of Brenipatide against a placebo to understand if it is safe and effective.
Birmingham, AlabamaAges 40–75 - NCT06577883Recruiting
New chest X-ray technique for lung cancer screening
This trial tests a new type of chest X-ray called tomosynthesis to improve lung cancer screening. It looks at people who are getting screened for lung cancer, have a suspicious spot on their lung, or have just been diagnosed—as long as they haven't been treated for lung cancer before.
San Diego, CaliforniaAges 30–85 - NCT06577753Recruiting
Chinese medicine study for interstitial lung disease
This study follows people with interstitial lung disease to learn more about how Chinese medicine can help. If you have ILD and are 18 or older, you may be able to join.
Zhengzhou, HenanAges 18 years+ - NCT06523673RecruitingPhase 3
SBRT for lung cancer with limited new growth
This trial tests whether a precise type of radiation called SBRT can control lung cancer that has started to grow in only a few new spots while you are on standard treatments. It may help you delay changing to a different treatment.
Hangzhou, ZhejiangAges 18 years+ - NCT07761910RecruitingPhase 2
Study of heart effects of radiation therapy using PET-CT for stage III lung cancer
This study looks at whether PET-CT scans can help detect heart damage caused by radiation therapy in patients with stage III lung cancer. If you're getting chemotherapy and radiation together, you may participate to help doctors find ways to reduce heart risks.
Indianapolis, IndianaAges 18 years+ - NCT07759583Recruiting
Breathing exercises for smog-related pneumonia
This study tests two breathing techniques—Buteyko breathing and incentive spirometry—to see which better improves oxygen levels, breathing difficulty, exercise tolerance, and mucus clearance in people with pneumonia caused by air pollution.
Lahore, Punjab ProvinceAges 25–40 - NCT07761377Recruiting
Using AI to spot lung scarring on CT scans
This study tests whether an AI tool can correctly find lung scarring (pulmonary fibrosis) on CT scans as well as doctors do. The results could lead to faster, more consistent detection of this condition.
TaichungAges 20 years+ - NCT07759856RecruitingPhase 2
Natural killer cells plus immunotherapy for small cell lung cancer
This trial tests combining natural killer (NK) cells with an immunotherapy drug as a maintenance treatment after standard chemotherapy for small cell lung cancer that has spread. The goal is to see if this combination can help keep the cancer from growing.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT07762573Recruiting
Predicting COPD progression with dynamic chest x-rays
This study looks at whether a special type of chest x-ray (called dynamic chest radiography) can help predict how chronic obstructive pulmonary disease (COPD) might progress. It may help doctors better understand the disease and plan treatment.
Guangzhou, GuangdongAges 30–85 - NCT07762157Recruiting
Home-based exercise program for lung recovery after COPD flare-ups
This study tests whether a supervised home-based exercise program, delivered via video calls, can help people recovering from a COPD flare-up feel stronger and breathe easier, compared with usual care. If you join, you'll have regular online sessions with a rehab team from home.
Hong KongAges 18 years+ - NCT06581562RecruitingPhase 1
Testing rituximab plus AB-101 for autoimmune diseases
This trial tests a new treatment (AB-101) combined with rituximab for people with certain autoimmune diseases like rheumatoid arthritis, pemphigus vulgaris, vasculitis, or lupus. It is for those who have not had success with standard therapies.
Plantation, FloridaAges 18 years+ - NCT06141226RecruitingPhase 2
New drug combo for immunotherapy-resistant lung cancer
This trial tests a combination of an immunotherapy drug (TQB2450), a targeted therapy (anlotinib), and chemotherapy for people with advanced non-small cell lung cancer whose cancer stopped responding to prior immunotherapy. It aims to find a new option when the first treatment didn't work anymore.
Huizhou, GuangdongAges 18–75 - NCT05769140Recruiting
Study how high altitude affects heart and breathing measures
This study looks at how exposure to high altitude changes measurements related to your heart and breathing. It may help scientists better understand health effects of altitude so they can improve safety and care.
Courmayeur, AostaAges 18 years+ - NCT02061787Recruiting
Exercise testing to assess outcomes in pulmonary hypertension
This trial studies how well a treadmill/breathing exercise test can measure health outcomes in people with certain types of pulmonary hypertension. It may help your care team judge your status and track changes over time.
BeijingAges 5–100 - NCT05766800RecruitingPhase 2
PD-1 plus chemotherapy before surgery for advanced lung cancer
This trial studies whether giving a PD-1 antibody together with standard chemotherapy before surgery can improve outcomes for people with stage IIIB–IIIC non-small cell lung cancer. It aims to shrink or control the cancer and make treatment before surgery more effective.
ShanghaiAges 18 years+ - NCT05844579Recruiting
Early breathing and mobilization support for ICU lung injury
This study looks at whether starting early movement and breathing-related care while in the ICU helps people with ARDS (a serious lung condition). You may be eligible if you recently needed a breathing machine and are expected to need it for a bit longer.
TokyoAges 16 years+ - NCT06105177Recruiting
Using blood tests to guide lung cancer care
This trial uses a simple blood test (liquid biopsy) to find tumor DNA in people suspected of having lung cancer. The goal is to learn if this test can help doctors make better treatment decisions without needing a tissue sample.
Heerlen, LimburgAges 18 years+ - NCT06151405Recruiting
Diet study for adults with asthma
This study tests whether a specially designed diet plan can help adults whose asthma is not well controlled. You will use a smartphone app to track your food and symptoms, and the study will provide dietary guidance.
Baton Rouge, LouisianaAges 18–65 - NCT06279741RecruitingPhase 1/Phase 2
Cell therapy to prevent lung disease in very premature babies
This study tests whether a special cell therapy (MSC-EVs) given to extremely premature babies can help prevent a serious lung disease called bronchopulmonary dysplasia (BPD). The treatment is given while the baby is still on a breathing machine.
BrusselsAges Up to 1 week - NCT07752173Recruiting
Recovery from breathing tube after surgery: day vs night
This study compares how well patients recover from the breathing tube (extubation) after surgery, depending on whether it happens during the day or at night. The goal is to see if there are more breathing complications at night so hospitals can improve care.
Kocaeli, IzmıtAges 18 years+ - NCT06348927RecruitingPhase 2
Sunvozertinib plus anlotinib for first-line EGFR-mutant lung cancer
This trial tests a combination of two oral drugs (sunvozertinib and anlotinib) as a first treatment for advanced lung cancer with certain EGFR mutations plus other gene changes. It aims to see if this combination works better than standard treatments.
Changsha, HunanAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,348 recruiting pulmonology studies from the U.S. registry right now, out of 9,933 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.