Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05589831Recruiting
Test breathing support and brain health in premature babies
This study checks how a type of breathing machine support affects brain health in very premature infants. It may help doctors choose safer breathing support strategies to protect the brain.
Toronto, OntarioAges 3 days+ - NCT05504278RecruitingPhase 1
Testing IBI351 with chemotherapy for KRAS G12C lung cancer
This Phase 1 study tests whether IBI351, a targeted medicine, can be safely given with standard chemotherapy to treat advanced lung cancer that has a KRAS G12C mutation. It’s mainly looking at safety and early signs of effectiveness, and may offer a new option if your cancer matches these features.
Jilin City, ChangchunAges 18–75 - NCT03791086Recruiting
BRIDGE study using health records and genetics for bronchiectasis
This study looks at how bronchiectasis (ongoing lung damage with mucus and infections) may happen by using your medical records and genetic information. It may help researchers find better ways to understand different bronchiectasis types and guide future treatments.
DundeeAges 18 years+ - NCT03236987RecruitingPhase 3
Clarithromycin versus azithromycin for lung MAC infection
This Phase 3 trial compares two antibiotics—clarithromycin and azithromycin—to treat lung infection caused by Mycobacterium avium complex (MAC). It may help by showing which antibiotic works better and is safer for people who need MAC treatment.
Amiens, PicardieAges 18 years+ - NCT03097575RecruitingPhase 1/Phase 2
Imaging-guided lung surgery using special near-infrared light
This trial tests whether using special near-infrared imaging can help surgeons better guide lung tumor removal during minimally invasive or open chest surgery. It may improve how accurately the surgical area is identified during the operation.
Boston, MassachusettsAges 18 years+ - NCT05623319RecruitingPhase 2
Pembrolizumab plus olaparib for extensive small cell lung cancer
This Phase 2 study tests whether combining pembrolizumab and olaparib can improve outcomes in people with extensive-stage small cell lung cancer. It mainly aims to shrink tumors and help control the cancer for longer.
Meldola, Forlì CesenaAges 18 years+ - NCT05515484RecruitingPhase 2
Test inflatable bag to help lungs work better when prone
This Phase 2 study tests whether using an inflatable air bag can improve how well the lungs stretch and work for people with ARDS while they are lying face-down (prone) on a ventilator. If you qualify, the study may help determine whether this positioning support improves breathing and lung comfort.
AmiensAges 18 years+ - NCT04837339Recruiting
Testing markers to predict problems after lung transplant
This study looks for lab “clues” that can help predict how well someone’s lungs will do after a lung transplant. It may help doctors spot transplant-related problems earlier so care can be planned sooner.
SuresnesAges 15 years+ - NCT05354570RecruitingPhase 2
Radiation for thymic cancer that has spread to lung lining
This Phase 2 study tests a precise type of chest radiation that targets cancer in the lung lining (pleura) while trying to protect healthy lungs and organs. It may help people with thymic cancer that has spread to the pleura, including cases that return after prior treatment.
Basking Ridge, New JerseyAges 18–79 - NCT05444699RecruitingPhase 4
Oral steroid for cold-related wheezing in children under 2
This trial tests whether a short course of oral prednisolone (an anti-inflammatory steroid) helps young children under 2 who have wheezing triggered by a rhinovirus cold. It aims to see if steroid treatment can improve symptoms after an emergency visit.
KokkolaAges 6 months–2 years - NCT04781894Recruiting
Ultrasound scan to check pleural lung lining changes
This study tests a special ultrasound method to measure stiffness in the lung lining (pleura) or fluid-related lesions. It may help doctors better tell what pleural problems look like, using a non-invasive scan.
TaipeiAges 20 years+ - NCT05193240Recruiting
Swallowing test to predict vocal cord paralysis after lung surgery
This study checks whether a simple swallowing test can forecast vocal cord paralysis after lung surgery, compared with a camera exam of the throat. If predictions are accurate, it may help doctors prevent or plan treatment for swallowing and voice problems.
RouenAges 18 years+ - NCT05115968Recruiting
Study tonsil cell changes in children with sleep apnea
This study uses a lab method called single-cell sequencing to look at tiny cells from tonsil tissue in children. It compares children with obstructive sleep apnea to children without it, to better understand what’s happening in the throat and how it may relate to needing tonsil removal.
Hong KongAges 6–11 - NCT05458934Recruiting
Breath test study for adults with lung or airway conditions
This study analyzes breath samples from adults with lung or airway problems. It may help researchers understand these conditions better by looking at what’s in your exhaled breath.
Zurich, Canton of ZurichAges 18 years+ - NCT05008965RecruitingPhase 2
Study drug for allergic asthma in adults
This Phase 2 trial tests whether FB825 can improve symptoms and safety in adults with moderate-to-severe allergic asthma. It is mainly for people whose asthma is not well controlled despite regular inhaler treatment.
Kaohsiung CityAges 18–75 - NCT03906617RecruitingPhase 4
Pain-relief shots for lung surgery: three drug options compared
This study compares different pain-relief medications given during lung surgery to see which one controls pain better. It may help people have less post-surgery pain after robotic wedge resection or lobectomy.
Camden, New JerseyAges 18–90 - NCT04099082Recruiting
Predicting lung scarring after a specific viral infection
This study looks at how your immune response to a particular virus (PIV) might predict future lung scarring called bronchiolitis obliterans. It may help doctors better identify who is at higher risk after a stem cell transplant.
Paris, Île-de-France RegionAges 18 years+ - NCT04031508Enrolling by invitationPhase 2
Omega-3 in an IV for newborns with breathing circulation problems
This trial tests whether giving an omega-3 fat medicine through an IV (along with standard care) improves breathing and blood-flow problems in newborns with congenital diaphragmatic hernia and persistent pulmonary hypertension. It may help reduce strain on the lungs and heart by targeting inflammation and blood-vessel changes.
Mexico City, Mexico CityAges 1 hour–2 weeks - NCT04206852Recruiting
Balloon treatment for chronic blood-clot lung vessel disease
This trial tests whether a procedure called balloon pulmonary angioplasty is safe and effective for people with chronic thromboembolic disease in the lungs, especially when surgery isn’t an option. If you have CTEPH, it may help improve lung blood flow and symptoms.
BeijingAges 18 years+ - NCT04467333Recruiting
Registry for lung cancer patients at a pulmonary hypertension center
This is a hospital registry study that collects information from people with lung cancer. It looks at pulmonary hypertension (high blood pressure in the lungs) in relation to lung cancer, which may help doctors understand risk and care needs.
Giessen, HesseAges 18 years+ - NCT03916302Recruiting
Pulmonary embolism registry study in Warsaw
This study keeps a registry (record) of people with a confirmed pulmonary embolism. Your information helps doctors better understand the condition and improve care.
WarsawAges 18 years+ - NCT04335773Recruiting
Study of COVID-19 in hospitalized children
This study looks at children (ages 0 to 18) who are in the hospital with suspected COVID-19. It aims to understand what factors affect outcomes and how the immune system responds.
LørenskogAges Up to 18 years - NCT04658498Recruiting
Respiratory muscle training to help patients come off the ventilator
This trial studies whether exercises for breathing muscles can help people who are having a hard time coming off a breathing machine in the ICU. It may help you breathe with less ventilator support once your body is stable enough.
LeuvenAges 18 years+ - NCT04582279Recruiting
Lung ultrasound test to rule out rejection after lung transplant
This study checks whether a painless lung ultrasound can help tell when rejection is unlikely after a lung transplant. If it works, it could reduce the need for other tests in people who feel well.
Jacksonville, FloridaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.