Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06815289Recruiting
MR-guided radiation for hard-to-treat central lung tumors
This trial tests a specialized radiation therapy that uses daily MRI scans to precisely target lung tumors located near the windpipe or esophagus. It aims to improve treatment accuracy while reducing side effects.
ZurichAges 18 years+ - NCT00710112Recruiting
Genetic risk study in very low birth-weight babies
This study looks at genetic differences to understand why some very low birth-weight babies develop certain health problems. It may help doctors predict risk and tailor care for these babies.
Milwaukee, WisconsinAges Any age - NCT07665892RecruitingPhase 1
Testing a new asthma drug in adults
This study tests a new medication called ASY202 for adults with stable asthma. The goal is to see if it's safe and how the body processes it. It may be an option for those who have not had a recent asthma attack or infection.
Glendale, ArizonaAges 18–55 - NCT05739617Recruiting
Breathing and sleep training for people with sleep apnea
This trial tests a comprehensive breathing and respiratory exercise program for newly diagnosed obstructive sleep apnea (OSA). It may help by improving sleep breathing and reducing apnea-related symptoms. You may be eligible if you recently learned you have OSA and meet age and health criteria.
Tainan, TaiwanAges 20–65 - NCT05341492RecruitingEarly Phase 1
CAR-T therapy for EGFR/B7H3-positive lung and triple-negative breast cancer
This early-phase trial tests CAR-T cells designed to find and attack tumors that show EGFR or B7H3 markers. It may help people with advanced lung cancer or triple-negative breast cancer after standard treatments.
Guangzhou, GuangdongAges 18–75 - NCT07660900Recruiting
Study of force feedback in robotic lung surgery
This study looks at how force feedback during robotic lung surgery might affect recovery. If you are having robotic lung surgery at Ohio State, you may be able to join.
Columbus, OhioAges 18 years+ - NCT07140003Enrolling by invitation
Comparing fluid and tissue cultures for pleural infection
This study compares how well cultures from the fluid around the lung work versus cultures from a tissue sample in people with infected pleural fluid. It may help doctors choose the best way to diagnose and treat the infection.
Alexandria, Chest DepartmentAges Any age - NCT07110129Recruiting
Testing a new tool to see if you're ready to come off the breathing machine
This study tests a new way to check if your breathing muscles are strong enough to safely remove the breathing tube. It uses a special patch to measure how well your diaphragm works, which may help doctors make better decisions about when to take the tube out.
CardiffAges 18 years+ - NCT07109570Recruiting
Checking breathing effort in ICU patients on a ventilator
This trial measures how your breathing muscles work while we try taking you off the breathing machine. The results could help doctors predict when you're ready to breathe on your own.
LeidenAges 18 years+ - NCT07143747Recruiting
Lung Imaging Study for Mild Asthma
This study uses special MRI and CT scans to take very detailed pictures of the lungs in people with mild asthma. The goal is to learn more about how asthma affects the lungs, which could help develop better treatments.
London, OntarioAges 17–35 - NCT03659019Recruiting
Database study for implanted phrenic nerve stimulators
This study collects information about people with long-term breathing problems who may receive an implanted device that helps control breathing. It helps doctors better understand who benefits and how these treatments are used in real life.
Paris, Île-de-France RegionAges 5 years+ - NCT03721822RecruitingPhase 1
Imaging how smoking affects lung inflammation in adults
This Phase 1 study uses special lung imaging to measure inflammation after different types of smoking or vaping. It looks at differences between people and may help researchers understand how smoking-related lung irritation develops.
Philadelphia, PennsylvaniaAges 18–45 - NCT05772845Recruiting
Study of quitting support for vaping and smoking withdrawal
This study looks at nicotine withdrawal symptoms in people who vape and/or smoke regularly. It may help improve how quitting support is tailored, based on how participants respond during the withdrawal period.
Buffalo, New YorkAges 21–50 - NCT06020716RecruitingPhase 4
Antibiotics for chronic wet cough in toddlers
This study tests whether the antibiotic Augmentin helps children aged 9 months to 3 years with long-lasting wet cough (more than 4 weeks). It aims to find better ways to treat and understand this common problem in toddlers.
ÅlesundAges 9 months–3 years - NCT03307018Recruiting
Check if bronchoscopy after lung surgery prevents complications
This study looks at whether doing a brief breathing-tube exam (bronchoscopy) after specific lung surgery can lower the chance of lung complications. It may help improve recovery and reduce post-surgery breathing problems.
Poznan, WielkopolskaAges 18–89 - NCT02354274Recruiting
New radiation approach for locally advanced lung cancer
This study tests a new way of giving radiation for people with locally advanced non-small cell lung cancer (NSCLC), along with a chemotherapy medicine (navelbine). It may help by improving how well the treatment controls the cancer in the chest while watching for side effects.
AalborgAges 18 years+ - NCT07120672Recruiting
Breathing tube removal success study
This study tests if a new method (PPI) can better predict when a patient is ready to have their breathing tube removed after a trial of spontaneous breathing.
IstanbulAges 18 years+ - NCT03657524Recruiting
Ultrasound heart imaging to help predict trouble weaning off a ventilator
This study uses a special ultrasound of the heart to help predict whether you might fail a trial of breathing on your own after being on a breathing machine. If the test can predict trouble early, clinicians may choose safer weaning plans.
MarseilleAges 18 years+ - NCT07159022Recruiting
High-flow nasal oxygen vs mask for people with belly fat having sedated stomach scope
This study compares two ways of giving oxygen during a sedated gastroscopy for people with visceral obesity (extra belly fat). One method uses a high-flow nasal cannula, the other a face mask. The goal is to see which keeps oxygen levels more stable.
ShanghaiAges 18–80 - NCT07164638Enrolling by invitation
Predicting fluid overload during prostate surgery
This study uses ultrasound to check for fluid overload in men having prostate surgery with spinal anesthesia. The goal is to see which ultrasound method works best to prevent complications.
TantaAges Any age - NCT06595459RecruitingPhase 4
Options 2 study: testing nicotine replacement or medicines to help smokers switch
This study compares different nicotine replacement options to help people who smoke switch away from cigarettes. It may be a good fit if you smoke at least 5 cigarettes a day, aren't ready to quit in the next month, and are willing to stop using other stop-smoking aids.
Madison, WisconsinAges 21 years+ - NCT02392442Enrolling by invitationPhase 2
Study drug-free lung irritation using endotoxin in healthy adults
This trial tests how putting a small amount of endotoxin into a specific part of the lung affects the body. It’s designed for healthy, nonsmoking adults, and may help researchers understand lung and immune responses.
Bethesda, MarylandAges 18–45 - NCT02825654Enrolling by invitation
Deployed Veterans Study of Service and Health
This study looks at how military service and deployment experiences relate to health and wellbeing in veterans who served after 9/11. It may help researchers understand which factors affect long-term health.
San Diego, CaliforniaAges Any age - NCT06245954Recruiting
Better diagnosis through lung sampling training
This trial studies whether standardizing the training for a lung biopsy procedure helps doctors better diagnose interstitial lung disease. You might be eligible if you have a suspected ILD diagnosis and your lung function and other health markers are within certain limits.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.