Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,348 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2836
- Phase 1458
- Phase 3420
- Phase 1/Phase 2310
- Phase 4212
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer183
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California384
- Alabama176
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,348 total
- NCT07681245Recruiting
Real-time laser imaging for lung tissue during surgery
This study tests a new laser imaging device that works with artificial intelligence to quickly analyze lung tissue during surgery. The goal is to see if it can give as accurate results as the standard method, which could help surgeons make faster decisions during the operation.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07682597Recruiting
Improving lung cancer screening in Nevada and Mississippi
This trial tests a new system (QUILS) to help state teams in Mississippi and Nevada improve lung cancer screening. You may join if you are part of a team working on this effort.
Greenville, MississippiAges 18–100 - NCT07683780Enrolling by invitation
Spinal stimulation and muscle training for cough after spinal cord injury
This study tests a combination of spinal cord stimulation and electrical muscle stimulation to help improve cough strength in people with a recent spinal cord injury. It may help you clear secretions more effectively.
Chicago, IllinoisAges 18–65 - NCT07687303Recruiting
Ventilator modes and stomach tube tolerance in ICU patients
This study looks at how different ventilator settings affect pressure in the belly and how well patients tolerate a feeding tube. It may help doctors choose the best ventilator mode for you.
DamanhūrAges 18–60 - NCT07683728Recruiting
Observational study of progressive pulmonary fibrosis (PPF) in China
This study is a registry that collects information from people in China who have progressive pulmonary fibrosis (PPF), a lung condition that gets worse over time. It aims to better understand the disease and help doctors improve care.
BeijingAges Any age - NCT07682610Recruiting
Improving lung cancer screening in Kentucky clinics
This study works with healthcare teams to improve how lung cancer screening is done. It uses surveys and feedback to find better ways to help patients get screened.
Ashland, KentuckyAges 18–100 - NCT07681973Recruiting
Smell training for loss of smell in sinus patients
This study tests whether smell training can improve your sense of smell and affect your immune system. It is for people with chronic sinus inflammation and nasal polyps who have lost their sense of smell.
Cleveland, OhioAges 18 years+ - NCT07685938RecruitingPhase 2
Medicines to prevent heart damage from radiation
This trial tests whether common heart medicines (statins or ACE-inhibitors) can protect the heart during cancer radiation therapy. It is for adults who are about to start chest radiation and have not taken these drugs before.
Chapel Hill, North CarolinaAges 18 years+ - NCT07684820RecruitingPhase 2
A study of ExPD-101 for COPD with chronic bronchitis and frequent flare-ups
This study tests an experimental drug (ExPD-101) given daily as a pill for 52 weeks for people with COPD who have chronic bronchitis and frequent flare-ups. It compares the drug to a placebo (inactive pill) to see if it reduces flare-ups and improves symptoms.
Phoenix, ArizonaAges 40–85 - NCT07680764RecruitingPhase 2
Imzokitug plus pumitamig and chemo for first-line advanced lung cancer
This trial tests a new combination of drugs (imzokitug, pumitamig, and platinum-doublet chemotherapy) as a first treatment for advanced or metastatic non-small cell lung cancer that has not spread to the brain. The goal is to see if adding imzokitug makes the standard treatment work better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07685106Recruiting
Cardiostory device test for heart failure in shortness of breath
This trial tests if a device called Cardiostory can tell if your shortness of breath (dyspnea) is caused by heart failure or something else. It's for people who started having trouble breathing in the last week.
Monastir, Monastir GovernorateAges 18 years+ - NCT07680790RecruitingPhase 3
New drug combination for advanced egfr lung cancer
This study tests a new drug (izalontamab brengitecan) combined with a standard targeted therapy (osimertinib) compared to standard treatments alone for advanced EGFR-mutant non-small cell lung cancer. It aims to see if the combination works better.
Beverly Hills, CaliforniaAges 18 years+ - NCT07685522Recruiting
Vibrato clot removal for pulmonary embolism safety study
This trial tests the Vibrato Aspiration System, a device that suctions blood clots from the lungs in people with a recent pulmonary embolism (PE). It aims to see if the procedure is safe and works well for removing clots.
Poznan, Greater Poland VoivodeshipAges 18–75 - NCT07687459RecruitingPhase 3
Oral treatment for idiopathic pulmonary fibrosis
This trial tests an experimental pill called rentosertib for people with idiopathic pulmonary fibrosis (IPF), a lung disease that causes scarring. The study aims to see if the drug can slow down the disease and improve breathing.
Hefei, AnhuiAges 40 years+ - NCT06660992RecruitingPhase 3
Study of HSK31858 for non-CF bronchiectasis
This trial tests a new medicine, HSK31858, for people with non-cystic fibrosis bronchiectasis (a lung condition causing chronic cough and infections). It aims to see if the drug reduces lung flare-ups and improves symptoms.
Guangzhou, GuangdongAges 18 years+ - NCT06442267RecruitingPhase 4
Comparing blood thinners for ECMO support
This trial compares three different blood thinners (heparin, argatroban, and enoxaparin) used during ECMO support. It aims to find the safest and most effective way to prevent blood clots while on ECMO.
Vienna, State of ViennaAges 18 years+ - NCT06664359Recruiting
Safer trigger point injections using ultrasound guidance
This study is testing a safer way to give trigger point injections — shots that relieve painful muscle knots — in the upper back. Researchers will use ultrasound to guide the needle and measure how close it is to the lungs, to avoid complications.
AnkaraAges 18–65 - NCT04684459RecruitingEarly Phase 1
CAR-T therapy for tumors with HER2 and PD-L1 markers
This early-phase trial tests CAR-T cells designed to attack tumors that have high HER2 and PD-L1. It may help people with certain solid cancers that have not responded well to standard treatment.
Chengdu, SichuanAges 18–75 - NCT05468242RecruitingPhase 2
Tislelizumab after lung cancer chemotherapy and radiation
This Phase 2 study tests tislelizumab (an immune medicine) given after chemotherapy and radiation for stage III non-small cell lung cancer that has not been treated before. It may help improve how well the cancer responds and how long patients can stay in remission, with or without an added medication called bevacizumab.
GuangzhouAges 18–75 - NCT07678086Recruiting
Breathing tube pressure and sore throat in children's appendix surgery
This trial tests whether carefully managing the pressure in the breathing tube during surgery can help prevent a sore throat in children after they have their appendix removed by keyhole surgery. It may help your child have a more comfortable recovery.
Ankara, YenimahalleAges 6–18 - NCT07677059RecruitingPhase 2
Long-term study of KT-621 for asthma patients from previous study
This trial is for people with asthma who already completed a previous study of the drug KT-621. It aims to see if taking KT-621 for a longer time is safe and helpful.
Miami, FloridaAges 18 years+ - NCT07671924RecruitingPhase 2
Testing nalbuphine extended-release for chronic cough
This trial tests whether an extended-release medication called nalbuphine can reduce coughing in people with chronic cough that hasn't improved with other treatments. You may be eligible if you've had a persistent cough for at least a year and have already tried treatments for conditions that could cause it.
AjaxAges 18 years+ - NCT07675265Recruiting
ARDS biomarker study
This study is for patients in the ICU with ARDS (a severe lung condition). It looks at biomarkers (special substances in your blood) to help understand different types of ARDS. You do not receive any treatment, but you help researchers learn more about the disease.
Urbana, IllinoisAges 18 years+ - NCT07679893RecruitingPhase 2
Inhaled nintedanib for idiopathic pulmonary fibrosis
This trial tests an inhaled form of nintedanib (a drug that helps slow lung scarring) for people with idiopathic pulmonary fibrosis (IPF). It may be an option for those newly diagnosed or already on stable treatment.
Windsor, OntarioAges 40–80
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,348 recruiting pulmonology studies from the U.S. registry right now, out of 9,933 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.