Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06455800Recruiting
Severe lung disease in childhood
This study looks at severe lung disease in children. It may help doctors better understand and treat these conditions.
OdenseAges 1 day–18 years - NCT06454955RecruitingEarly Phase 1
PET scan imaging study for solid tumors using a new probe
This trial tests a new imaging agent that targets a protein called B7-H3 found on many solid tumors. It uses PET/CT to help doctors see and stage tumors more clearly.
Beijing, Beijing MunicipalityAges 18–75 - NCT07423338Recruiting
Monitoring breathing muscles in respiratory failure patients
This study tests a new way to monitor breathing muscles in patients who need extra oxygen or breathing support, like a mask or high-flow oxygen. It may help doctors better understand how to treat respiratory failure.
LondonAges 18 years+ - NCT06603584Recruiting
Studying wheezing patterns in young children
This study looks at different kinds of wheezing in young children (ages 1 to 5) to better understand what causes it and how to treat it. If your child has had wheezing more than once, this research could help find patterns that lead to better care.
SohagAges 2–6 - NCT06598930Recruiting
Nurse-led follow-up after mild lung blood clot
This study compares two ways of following up after a non-severe pulmonary embolism: standard medical care alone versus intensive monitoring that includes an advanced practice nurse. The goal is to see if the nurse-led follow-up improves your recovery and quality of life.
DijonAges 18 years+ - NCT07427121Recruiting
Exercise study for healthy non-smokers on a breathing machine
This study looks at how physical therapy and exercise affect people who are on a breathing machine (mechanical ventilation). It may help researchers find better ways to help patients recover while on a ventilator.
Gainesville, FloridaAges 25–80 - NCT06988644Recruiting
Smoking cessation support for health workers
This study offers counseling at work to help health professionals quit smoking. It tests whether talking with a counselor at your workplace makes it easier to stop smoking for good.
Grenoble, isereAges 18 years+ - NCT06592235Recruiting
Lung health, climate change, and physical activity awareness
This study looks at how much people with long-term lung diseases know about climate change, heat waves, air pollution, and physical activity. It will help doctors understand how these factors affect your health and how to better support you.
Ankara, AnkaraAges 18 years+ - NCT06595043Recruiting
Testing different tube angles for one-lung breathing
This study is testing a special breathing tube that blocks one lung during surgery. It looks at whether the angle of the tube affects how well it works for right-sided lung operations. If you are having a right lung surgery with a camera, you may be able to join.
ShenyangAges 18–65 - NCT05991206Recruiting
Atezolizumab with chemo before surgery for lung cancer
This study tests a combination of the immunotherapy drug atezolizumab with standard chemotherapy given before surgery for people with stage II to IIIB non-small cell lung cancer that can be removed. The goal is to see if this approach helps shrink tumors and improve outcomes.
Changsha, HunanAges 18 years+ - NCT07428694Recruiting
Detecting air leaks during breathing support
This trial tests a machine learning tool to detect if air is leaking while using a breathing machine at night. It may help people who use a non-invasive ventilator at home get better care.
OsloAges 18 years+ - NCT07429851Recruiting
Comparing thymus, lung, and pancreas neuroendocrine tumors
This trial is studying well-differentiated high-grade neuroendocrine tumors that start in the thymus, lung, or pancreas. It compares these tumors to understand them better and find better treatments.
Milan, ItalyAges Any age - NCT06903052Recruiting
App for parents managing child's breathing tube symptoms
This trial tests a mobile app that helps parents care for their child who needs a breathing tube at home. The app provides support and tips for managing symptoms, so parents feel more confident and prepared.
Kowloon, KowloonAges 2–18 - NCT06443658RecruitingPhase 3
The ELTGOL breathing technique: Clearing phlegm faster
This study tests whether inhaling a saltwater spray before a special breathing exercise (ELTGOL) helps people with bronchiectasis cough up phlegm more easily. It's for adults who have daily phlegm, recent flare-ups, and have not smoked much.
GironaAges 18 years+ - NCT07424807Recruiting
Comparing two needle techniques in chest lymph node biopsy
This trial compares two different ways of moving the needle during an EBUS-TBNA procedure to see which method gets better tissue samples from enlarged lymph nodes in the chest. It may help doctors improve the accuracy of diagnosis for conditions like lung cancer or infection.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07425795RecruitingPhase 2
Tislelizumab with chemo and radiation for first-line extensive SCLC
This trial tests a combination of an immunotherapy drug (tislelizumab), chemotherapy, and then radiation to the chest for people with extensive-stage small cell lung cancer who haven't had prior treatment. The goal is to see if this approach helps control the cancer longer.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06947694RecruitingPhase 2
Testing radioimmunotherapy combinations for lung cancer with metastases
This trial explores whether combining radiation therapy with immunotherapy can trigger an immune response that shrinks tumors throughout the body (abscopal effect) in people with non-small cell lung cancer that has spread to 3 to 6 other sites. It tests different patterns of these treatments to see which works best.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06434324Recruiting
Saline rinse for lung infection treatment
This study tests whether rinsing the infected space around the lung with salt water (saline) before giving enzyme medicine helps clear the infection better than just the enzyme medicine alone. It's for people with a serious lung infection (empyema) that requires a chest tube.
Rochester, MinnesotaAges 18 years+ - NCT07415005RecruitingPhase 2
Lorlatinib and local therapy for ALK-positive lung cancer
This study combines a daily targeted pill (lorlatinib) with a short course of radiation or surgery to treat ALK-positive lung cancer. The goal is to see if this two-step approach delays the cancer from growing.
Houston, TexasAges 18 years+ - NCT06583148Recruiting
Smoke-Free Home Program for Tribal Communities
This study aims to help make homes smoke-free in American Indian communities. It tests a program that supports people who smoke or live with a smoker to create a healthier home environment.
Atlanta, GeorgiaAges 18 years+ - NCT07413042RecruitingPhase 1
Radiation drug combined with immunotherapy for extensive-stage small cell lung cancer
This trial tests a combination of a radioactive drug ([225Ac]Ac-DOTATATE) and an immunotherapy drug (Tislelizumab) as maintenance treatment for people with extensive-stage small cell lung cancer (ES-SCLC) whose tumors have a specific protein (SSTR). If you have completed first-line treatment and your cancer shows SSTR on a PET scan, this study may be an option.
Beijing, Beijing MunicipalityAges 18–80 - NCT07413718Recruiting
Breathing muscle training for ALS patients
This study tests whether a special breathing muscle training can help people with ALS maintain lung function. It may benefit patients diagnosed recently with spinal ALS and good breathing capacity.
Donostia / San Sebastian, GipuzkaAges 18–85 - NCT07409727RecruitingPhase 4
Acetylcysteine inhalation to prevent pneumonia in ventilated patients
This trial tests if breathing in a medication called acetylcysteine can help prevent lung infections in patients who are on a breathing machine. If you or a loved one is on a ventilator, this treatment might reduce the chance of getting ventilator-associated pneumonia.
CairoAges 18–64 - NCT06437444Recruiting
Asthma crisis in children: impact of a new care pathway
This trial looks at how a new care pathway affects children with asthma attacks in emergency rooms, hospitals, and primary care. It aims to improve care for children aged 2 to 14 who have had an asthma flare-up.
Barakaldo, BizkaiaAges Any age
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.