Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT03465774Recruiting
Doxycycline added to a chest drain for cancer fluid buildup
This trial studies whether adding an antibiotic called doxycycline to an indwelling chest drain improves symptoms and fluid control in people with cancer-related fluid around the lungs. It’s mainly for patients who are getting this drain placed and can complete brief symptom check-in questions.
Houston, TexasAges 18 years+ - NCT03467360RecruitingPhase 1
Adding an acetazolamide-type drug to lung cancer radiation and drugs
This Phase 1 trial tests whether blocking an enzyme (with an acetazolamide-like medicine) can be safely combined with standard treatment for small cell lung cancer that has not spread. The goal is to see if the treatment can be given safely and to learn early signs of benefit.
NiceAges 18 years+ - NCT03478553Recruiting
Study of genes in people with pulmonary fibrosis
This study looks at genetic (inherited) factors related to pulmonary fibrosis, especially idiopathic pulmonary fibrosis (IPF). It may help researchers understand why some families are more affected and could guide future testing or treatments.
Aurora, ColoradoAges 18 years+ - NCT03482245Recruiting
Study how body clock proteins affect immune responses in infections
This study looks at how your body’s daily “clock” proteins may influence your immune response during certain serious infections requiring hospital care. If you qualify, researchers will compare immune signals during treatment to better understand what could improve care.
St Louis, MissouriAges 18–65 - NCT03478826Recruiting
Donate blood samples for a lung disease research biobank
This study builds a “biobank,” a storage of blood and related samples, from people with lung interstitial lung diseases or other lung scarring diseases. Your samples help researchers study these conditions and improve future care.
Rochester, MinnesotaAges 18 years+ - NCT03492762RecruitingEarly Phase 1
PET scan study of lung inflammation in never or current smokers
This early research study uses special PET scans to look at lung inflammation linked to a target called CCR2. It may help researchers understand inflammation biology and future treatments, using scan results instead of an investigational drug.
St Louis, MissouriAges 21 years+ - NCT03500731RecruitingPhase 1/Phase 2
Lung and bone marrow transplant for lung and blood failure
This Phase 1/2 study tests a special lung-and-bone-marrow transplant approach for people with severe lung disease and bone marrow failure (low blood counts). The goal is to see if the treatment is safe and whether it can improve outcomes when standard long-term immune-suppressing medicines are a poor fit.
Pittsburgh, PennsylvaniaAges 18–60 - NCT03504007Recruiting
Patient registry for people starting blood thinners after a clot
This registry collects information from people who had a clot (venous thromboembolism) and start blood thinners soon after diagnosis. It may help doctors better understand treatment patterns and outcomes after early blood-thinner use.
Rochester, MinnesotaAges 18 years+ - NCT03505216Recruiting
Child lung symptom clinic registry for Swiss families
This study collects information from children and teens (up to age 16) who are seen in a children’s lung clinic for breathing or respiratory problems in Switzerland. The goal is to better understand these conditions in everyday care, which may help improve future diagnosis and treatment.
ViennaAges birth–16 years - NCT03515031Recruiting
Compare two oxygen masks for breathing failure from pneumonia
This trial compares two ways of giving oxygen—high-flow nasal tubes versus a Venturi face mask—for adults with pneumonia causing acute breathing failure. It aims to see which method works better to improve breathing and recovery.
BergamoAges 18 years+ - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03535545RecruitingPhase 1
PET-MRI imaging test in lung cancer and lung disease
This Phase 1 study tests a radioactive imaging agent to help doctors see disease activity in the lungs using PET/MRI scans. It includes healthy volunteers and people with lung cancer, idiopathic pulmonary fibrosis, lung transplant–related lung problems, or certain medication-related lung inflammation.
Boston, MassachusettsAges 18–80 - NCT03539705Recruiting
Food Allergy Registry for People of All Ages
This study is a food allergy registry where you can share your experiences and information. It may help researchers better understand food allergies across different ages.
Palo Alto, CaliforniaAges birth–100 years - NCT03551951Recruiting
Testing cancer cells and DNA in blood, urine, and bone marrow
This study looks for cancer-related cells and DNA in samples like blood, urine, and (for some) bone marrow. The goal is to see whether these tests can help detect or track solid cancers with minimal added procedures.
Columbia, MissouriAges 18 years+ - NCT03556228RecruitingPhase 1/Phase 2
Tested medicine for tumors with TrkA changes, alone or with pembrolizumab
This early-phase study tests VMD-928, a targeted cancer medicine, for cancers that have TrkA-related tumor changes. It may be given by itself or with pembrolizumab to see if it can shrink tumors when standard treatments have not worked.
Santa Rosa, CaliforniaAges 18–80 - NCT03562052Recruiting
Lung cancer screening for high-risk workers and smokers
This study offers lung cancer screening (using scans) for people at high risk due to smoking history and workplace exposure to cancer-causing substances. It aims to find lung cancers earlier and understand who benefits most from regular screening.
BordeauxAges 55–74 - NCT03561818Recruiting
Home or hospital physiotherapy for bronchiectasis efficiency
This study compares how well breathing/airway physiotherapy works when done at home versus in a hospital for people with bronchiectasis. It may help determine which approach is easier and works best while you’re stable.
Istanbul, ZeytinburnuAges 18–75 - NCT03563976Recruiting
Imaging study for lung cancer outcomes
This study looks at medical images from people with lung cancer to see how image findings relate to outcomes. It may help doctors better understand which imaging features predict results for patients.
Dallas, TexasAges 18–99 - NCT03568669Recruiting
Testing thinking and learning in congenital central hypoventilation syndrome
This study looks at thinking and memory in people with congenital central hypoventilation syndrome (CCHS) to better understand how the condition affects the brain. It may help researchers measure changes over time and guide future care.
Los Angeles, CaliforniaAges 3–85 - NCT03581370RecruitingPhase 3
Short vs longer infusion antibiotic for ventilator lung infection
This Phase 3 study compares a shorter vs longer drip schedule of the antibiotic ceftolozane-tazobactam in ICU patients with a specific type of ventilator-associated pneumonia caused by Pseudomonas. It aims to find which infusion time works as well (or better) while treating the infection safely.
ToulouseAges 18 years+ - NCT03582124RecruitingPhase 1/Phase 2
Panitumumab dye to help find lung cancer during surgery
This trial tests a special dye drug (panitumumab-IRDye800) that may help surgeons better see lung cancer areas while operating. If it works, it could improve how well cancer tissue is found and removed during planned lung surgery.
Palo Alto, CaliforniaAges 19 years+ - NCT03587961RecruitingEarly Phase 1
Personalized testing to find the best CF medicine for you
This early study tests an individualized approach (“theratyping”) to match your cystic fibrosis (CF) to the CFTR medicine that may work best for your specific genetic change. It may help find a more tailored treatment plan and see how your body responds, while using medicines that are already approved for some people with CF.
Birmingham, AlabamaAges 6 years+ - NCT03606200Recruiting
Join a registry for primary ciliary dyskinesia
This study is a registry that collects information from people diagnosed with primary ciliary dyskinesia. It may help researchers better understand the condition over time and improve future care.
BernAges Any age - NCT03609580RecruitingPhase 1/Phase 2
Testing Flomax to prevent urine retention after chest surgery
This study looks at whether starting Flomax around the time of thoracic (chest) surgery can help prevent a painful problem called urinary retention (not being able to pee after surgery). You might benefit if you’re at risk of not urinating after your operation and can safely take Flomax.
Hackensack, New JerseyAges 50 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.