Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT05119842Recruiting
Implant study for permanent voice weakness from vocal cord closure
This study tests a voice implant device in people with permanent vocal cord weakness (UVFP) who have trouble closing their vocal cords. It aims to improve voice strength and reduce voice-related burden, while checking safety over the study period.
Phoenix, ArizonaAges 18–80 - NCT04886401Recruiting
Study predicting response to pembrolizumab in advanced lung cancer
This study looks back at prior treatment to learn which patients with advanced non-small cell lung cancer (NSCLC) are more likely to respond to pembrolizumab, an immune therapy given up front. The results may help doctors better predict who benefits from this treatment.
BrestAges Any age - NCT05204888Recruiting
Home breathing device study for COPD patients after recent flare-up
This study tests whether a home high-flow nasal breathing device (myAirvo 3) helps people with COPD who recently needed hospital care for a flare-up. You would use the device at home and track symptoms, oxygen levels, and heart rate daily to see how well it works.
Birmingham, AlabamaAges 30 years+ - NCT06286189RecruitingPhase 1/Phase 2
Testing trazodone for sleep apnea
This trial tests whether the medication trazodone can help people with moderate to severe obstructive sleep apnea (OSA). If you have OSA and are not taking certain medications or have other sleep disorders, you may be able to join.
Boston, MassachusettsAges 21–70 - NCT07430124Recruiting
Two breathing methods during balloon dilation for airway procedure
This study compares two ways of delivering breaths during a balloon dilation procedure to see which works better and is safer for your lungs.
AnkaraAges 18–65 - NCT07426718Recruiting
Breath test for airway inflammation in lung diseases and healthy people
This study is testing a simple breath test (Inflammacheck device) to see if it can measure airway inflammation in people with various lung conditions, including lung cancer, pneumonia, asthma, and COPD, as well as healthy volunteers. It aims to find better ways to diagnose and monitor respiratory diseases using your breath.
Portsmouth, HampshireAges 18 years+ - NCT07431112RecruitingPhase 1
Study of AIR-001 for adults with alpha-1 antitrypsin deficiency
This study tests an experimental RNA-based medicine (AIR-001) for people with a genetic form of alpha-1 antitrypsin deficiency (AATD). It aims to see if the drug can help boost your body's own protective protein levels and may slow lung damage.
MelbourneAges 18–74 - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07434050RecruitingPhase 3
Study of XW003 for obesity with sleep apnea on CPAP therapy
This trial tests an investigational drug called XW003 to see if it helps people with obesity and obstructive sleep apnea who are already using a positive airway pressure (PAP) machine, like CPAP. It aims to improve weight loss and sleep apnea symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07430956RecruitingPhase 3
Stroke prevention in atrial fibrillation without standard blood thinners
This trial tests a new medication to prevent strokes and blood clots in people with atrial fibrillation (an irregular heartbeat) who cannot safely take standard blood thinners. The drug works by blocking a different clotting factor, which may lower bleeding risks.
Dothan, AlabamaAges 18 years+ - NCT07431853RecruitingPhase 2
Study of an mRNA flu vaccine for adults
This trial is testing a new mRNA-based flu vaccine in healthy adults. It aims to see if the vaccine is safe and effective at preventing influenza.
Mobile, AlabamaAges 18 years+ - NCT07431840Recruiting
Immune protein for respiratory infections in older adults
This trial tests whether an immune defense protein can help reduce upper respiratory infections (like colds) in people aged 60 and older. It may be a good fit if you get colds or flu-like symptoms several times each season.
Los Angeles, CaliforniaAges 60 years+ - NCT07435038RecruitingPhase 1/Phase 2
Trial of BPI-572270 for advanced solid tumors with RAS mutations
This trial tests a new drug, BPI-572270, for people with advanced solid tumors that have specific changes in the RAS gene. It may be an option if you have already tried standard treatments for your cancer type.
Blacktown, New South WalesAges 18 years+ - NCT07433283RecruitingPhase 1/Phase 2
Iron nanoparticle injection for advanced solid tumors
This trial tests a new treatment for advanced solid tumors that uses tiny iron particles guided by carbon nanoparticles, injected directly into the tumor. It may be an option if standard treatments have stopped working or aren't available, and you have a tumor that can be safely injected.
Beijing, Beijing MunicipalityAges 18–80 - NCT07432477Recruiting
Lung opening techniques after heart surgery
This trial compares two methods of opening the lungs (recruitment maneuvers) after heart-lung bypass to see which works better. The study aims to help patients recover their lung function more quickly after cardiac surgery.
SamsunAges 18–80 - NCT07432373Recruiting
Comparing clot-busting drugs for lung infections
This trial tests two combinations of medicines for people with infected fluid around the lung that isn't draining well through a chest tube. The goal is to see which combination works better to clear the infection and improve recovery.
Cheras, Kuala LumpurAges 18 years+ - NCT07431580Recruiting
How low oxygen affects heart function in asthma
This study tests how your heart's right ventricle adapts when you breathe lower-oxygen air (like at high altitude). If you have well-controlled asthma, researchers want to see if your heart handles the challenge differently.
Zurich, Canton of ZurichAges 18–80 - NCT07434869Recruiting
Blood and image markers for ECP response in lung transplant CLAD
This study looks at whether blood tests and MRI scans can predict how well ECP (a blood-filtering treatment) works for people with CLAD after a lung transplant. If you’ve been prescribed ECP for CLAD and haven’t had it before, you may be able to help researchers find better ways to tailor treatment.
Boston, MassachusettsAges 7 years+ - NCT07431567Recruiting
How low oxygen affects heart function in healthy adults
This study tests how your heart’s right ventricle handles low oxygen (like at high altitude) in healthy adults. You will be exposed to a low-oxygen environment for a short time to see how your heart responds.
Zurich, Canton of ZurichAges 18–80 - NCT07425795RecruitingPhase 2
Tislelizumab with chemo and radiation for first-line extensive SCLC
This trial tests a combination of an immunotherapy drug (tislelizumab), chemotherapy, and then radiation to the chest for people with extensive-stage small cell lung cancer who haven't had prior treatment. The goal is to see if this approach helps control the cancer longer.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT07434908Recruiting
Study of HBP and lung fluid in ICU patients
This trial looks at a protein called HBP in the blood and how it relates to fluid in the lungs. You can join if you are over 18 and already have a special heart monitor called PiCCO in place.
ÖstersundAges 18 years+ - NCT07431060Recruiting
Modified LCH treatment with or without Luvometinib for children
This trial tests a new drug called Luvometinib added to a standard chemotherapy regimen for children with Langerhans cell histiocytosis that affects multiple parts of the body. The goal is to see if the combination works better than the standard treatment alone.
ChengduAges birth–18 years - NCT07434518Recruiting
Study of adebrelimab for advanced small cell lung cancer
This study looks at how well adebrelimab works and how safe it is in real-world settings for people with advanced small cell lung cancer that has spread. It may help doctors understand if this treatment is a good option for patients like you.
ShanghaiAges 18–100 - NCT07434583Recruiting
Force sensor study for laryngeal surgery patients
This trial tests a force sensor tool used during laryngeal surgery (surgery on the voice box) via direct laryngoscopy (a tube inserted through the mouth). It may help surgeons apply the right amount of force to reduce tongue injuries.
San Francisco, CaliforniaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.