Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT03615742RecruitingPhase 4
Study how diesel fumes affect asthma medicine response
This trial looks at how diesel exhaust exposure can change how well asthma “steroid” medicine works in your body. It may help researchers understand why some asthma symptoms are harder to control and guide better treatment strategies.
Vancouver, British ColumbiaAges 19–49 - NCT03621566Recruiting
Sleep apnea registry for adults with non-obstructive events
This study builds a registry to learn more about sleep apnea patterns, especially cases where most breathing events are not caused by blocked airway tissue. You may be able to join if you’re an adult with a specific sleep test result.
AalstAges 18 years+ - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT03623958Recruiting
Image-guided minimally invasive lung surgery versus standard surgery
This study compares an image-guided version of a minimally invasive lung surgery to the standard approach for removing small lung nodules. It may help doctors improve planning and targeting of the nodule during surgery.
Boston, MassachusettsAges 18 years+ - NCT03631420RecruitingPhase 1
Stem cell treatment to prevent lung disease in very premature babies
This Phase 1 trial tests whether giving stem cells into a breathing tube is safe and may help prevent bronchopulmonary dysplasia (BPD), a serious lung condition in very premature infants. It focuses on babies soon after birth who already need breathing support and are at risk.
TainanAges 3 days–2 months - NCT03642002Recruiting
Music therapy for adults on breathing machines in the ICU
This trial tests whether music therapy can improve comfort and recovery for adults who need a breathing machine (mechanical ventilation) in the ICU for at least 48 hours. It may help with stress, mood, and other ICU-related symptoms while you are in critical care.
New York, New YorkAges 18 years+ - NCT03647098Recruiting
Lung cancer survival study for adults receiving study treatment
This trial is looking at how well a lung cancer treatment improves survival. It enrolls adults with confirmed lung cancer who can safely take the study medicines and have cancer that can be measured on scans.
Changsha, HunanAges 18 years+ - NCT03655015Recruiting
Using patient tumor cells to test lung cancer treatment response
This study looks at lung cancer samples you provide to see how tumor cells respond to treatment. It may help researchers find better ways to choose treatments for lung cancer by testing response in a lab model.
San Antonio, TexasAges 18 years+ - NCT03657693Recruiting
MRI test in newborns with breathing problems (BPD)
This study uses MRI (a special scan) to look at babies with bronchopulmonary dysplasia, a long-term breathing condition that can happen after being in the NICU. It aims to learn more about what’s happening in the lungs and how MRI can be used safely in these babies.
Cincinnati, OhioAges Up to 4 months - NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT03670472Recruiting
Gene therapy for cystic fibrosis with specific CFTR mutations
This study looks at correcting “stop” mistakes (nonsense mutations) in the CFTR gene, which can cause cystic fibrosis. If your CFTR test shows the exact type of mutation the study needs, you may be able to take part.
AmiensAges 8 years+ - NCT03691480Recruiting
Treating a collapsed lung at home: valve pigtail vs air removal
This study compares two ways to treat a first-time, spontaneous collapsed lung (pneumothorax): a small tube with a one-way valve versus removing air with a needle. It aims to see which approach works better and is easier to manage for people treated as outpatients.
LorientAges 18–50 - NCT03691857Recruiting
Ultrasound computer tool for sudden breathing trouble in the ER
This study tests how well a computer-guided ultrasound method can quickly identify the cause of sudden breathing difficulty in the emergency room. It may help doctors make faster, more accurate decisions for treatment.
Châlons-en-ChampagneAges 50 years+ - NCT03702309Recruiting
Banking and testing blood samples to study cancer
This study collects blood samples to “test and store” (bank) information that may help doctors understand cancer in the future. You might be able to join if you’re an adult with confirmed cancer or a higher-than-usual risk for cancer.
Toronto, OntarioAges 18 years+ - NCT03704207Recruiting
Testing a diagnostic workup to guide care for PCD
This study checks whether using “PCD diagnostics” helps clinicians make better care decisions for people being evaluated for PCD. You might be able to join if you’re referred for PCD diagnosis and can complete the study steps.
Nashville, TennesseeAges 1 year+ - NCT03725956Recruiting
Sleep study before and after nasal polyp surgery
This study uses a sleep test to look at breathing and sleep patterns in people with nasal polyps who need surgery because medicine didn’t help. It may help doctors understand how nasal polyps affect sleep and how surgery changes those sleep measurements.
LilleAges 18 years+ - NCT03735563RecruitingPhase 4
Less invasive surfactant timing with different pre-medications
This study tests whether giving a pre-medication before a less invasive lung treatment (surfactant) improves breathing in premature babies. It may help some babies avoid more invasive ventilation while still getting the lung medication they need.
OuluAges Any age - NCT03736707Recruiting
Testing two breathing machines in very preterm babies
This study compares two ways of helping very preterm infants breathe: a special high-frequency ventilation method versus the standard mechanical ventilator. It aims to see which method works better for preterm babies with breathing failure soon after birth.
Chongqing, Chongqing MunicipalityAges 1 minute–1 hour - NCT03736382Recruiting
Study how mild low-oxygen affects sleep apnea and blood pressure
This trial studies whether mild, controlled low oxygen during sleep can change sleep apnea symptoms and related blood pressure issues. It mainly looks at people with newly diagnosed, untreated sleep apnea and early high blood pressure.
Detroit, MichiganAges 18–60 - NCT03740256RecruitingPhase 1
HER2-targeted oncolytic virus plus custom immune cells for solid cancers
This Phase 1 study tests a treatment plan that combines a virus designed to attack cancer with your own custom immune cells that target HER2. It aims to shrink advanced HER2-positive solid tumors (and make future options safer/more effective).
Houston, TexasAges 18 years+ - NCT03740503Recruiting
Study genes in people who respond unusually to treatment
This study looks at stored tumor samples to understand why some people respond much better or much worse than expected. The goal is to learn what the tumor’s genes might be telling doctors about response to treatment.
Toronto, OntarioAges 18 years+ - NCT03742687Recruiting
Testing a shorter, stronger radiation schedule for lung cancer
This trial studies a different way to deliver radiation to people with locally advanced, non-operable non-small cell lung cancer. It may help by aiming to treat the tumor effectively with a different radiation timing and dose pattern.
AarhusAges 18 years+ - NCT03748069Recruiting
Study of complications from flu and lung Aspergillus infection
This study looks closely at how influenza (the flu) and a specific kind of lung fungus called Aspergillus affect people who are sick in the ICU with breathing problems. It may help doctors better understand the cause and improve treatment for severe lung infections.
LeuvenAges 18 years+ - NCT03753412Recruiting
Rehab program for adults after ICU recovery on ECMO
This trial looks at a recovery and rehabilitation approach for adults who were very sick and needed a machine called ECMO to support breathing and heart function. It may help people regain strength and function after a severe ICU illness.
LondonAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.