Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06725186Recruiting
Emotion coaching for teens with ADHD
This study tests a program that helps teens with ADHD learn to manage their emotions more effectively. You and your child would take part in weekly sessions with a coach who teaches emotion regulation skills.
Blacksburg, VirginiaAges 11–16 - NCT06724289RecruitingEarly Phase 1
Psilocybin for prolonged grief
This trial tests if a single dose of psilocybin (a psychedelic drug) can help people with prolonged grief disorder. You'll receive counseling and be observed in a safe setting.
Charlottesville, VirginiaAges 18–65 - NCT06725706Recruiting
Beta-amyloid PET scan for amyloid-related diseases
This trial is testing whether a special scan (beta-amyloid PET/CT) can help detect abnormal protein clumps in the brain that are linked to certain diseases, including cancer. The scan might help doctors better understand and track these conditions.
Hefei, AnhuiAges 18–80 - NCT06726200RecruitingEarly Phase 1
Comparing buprenorphine formulations for fentanyl addiction
This study tests two different forms of buprenorphine (a medication for opioid addiction) to see which works better for people who use fentanyl or other strong synthetic opioids. If you are seeking treatment for opioid use, this trial may help you find the most effective option.
New York, New YorkAges 18–65 - NCT06725160Recruiting
Happiness coaching for moms and their young children
This trial tests a program that helps mothers with depression learn positive parenting skills to boost their child's emotional well-being. If you are a mother with high depressive symptoms and have a child between 4 and 6 years old, this study may be an option.
Pittsburgh, PennsylvaniaAges 4–99 - NCT06718764Recruiting
Bedside brain monitor study for sedated ICU patients
This study tests a new bedside monitoring system that tracks brain activity in ICU patients who are on a breathing machine and receiving sedative medications. It aims to help doctors better manage sedation and improve patient care.
New York, New YorkAges 18 years+ - NCT06725277Recruiting
Observing ketamine and Spravato for depression
This study follows people who are already taking or about to start IV ketamine or Spravato® for hard-to-treat depression. Researchers want to learn more about how these treatments work in real life.
Milford, ConnecticutAges Any age - NCT06722976Enrolling by invitation
Digital health and exercise for staying independent longer
This trial tests a program that combines digital health tools with exercise to help older adults stay active and independent. It may be a good fit if you are 65 or older and can walk or move around without major difficulty.
Covilha, CovilhãAges 60 years+ - NCT06722287Recruiting
Phone support for family caregivers in Thailand
This study tests a mobile program to support the mental health of family caregivers in Thailand. You participate from home using your phone.
BangkokAges 18–80 - NCT06726187Recruiting
Autism and personality in adults
This study looks at personality traits and disorders in adults with autism. You and someone who knows you well will answer questions to help researchers understand how autism and personality relate.
RotterdamAges 18 years+ - NCT06718491Recruiting
A smartphone program to reduce heavy drinking for people on opioid treatment
This study tests a brief smartphone-based program to help people reduce heavy drinking while they are receiving medication for opioid use disorder (MOUD). It aims to improve both alcohol and mental health outcomes.
Columbus, OhioAges 18 years+ - NCT06720090RecruitingEarly Phase 1
Light therapy for obsessive-compulsive disorder (OCD)
This study tests whether morning light therapy can help people with OCD who have late bedtimes. It aims to improve symptoms by shifting your body's internal clock earlier.
St Louis, MissouriAges 17–35 - NCT06723834Enrolling by invitation
Service Dogs and PTSD Therapy for Military Members
This study tests if pairing a psychiatric service dog with a type of talk therapy helps military-connected people with PTSD. It’s for those who have been approved to get a service dog and are not already in the same therapy.
Tucson, ArizonaAges 18 years+ - NCT06720753Recruiting
Skill use study for teens who self-injure
This study uses a smartphone app to track how teens cope with distress in real time. It aims to understand what helps reduce self-injury and suicidal thoughts, so better support can be offered.
Salt Lake City, UtahAges 13–18 - NCT05692830Recruiting
Test a wearable patch to estimate blood alcohol level
This study checks how accurately a new wearable skin patch estimates your blood alcohol level. It uses larger human testing and computer methods to improve the patch’s accuracy.
Champaign, IllinoisAges 21 years+ - NCT06002022Recruiting
How hormone therapy affects your quality of life
This study looks at how hormone therapy affects your quality of life. You'll answer questionnaires about your symptoms and well-being over time.
ValenciaAges 18–75 - NCT06503016RecruitingPhase 3
Phosphocreatine for medical emergency team patients
This study tests if a medicine called phosphocreatine helps people in the hospital who have a serious heart or lung emergency. It aims to see if the medicine can improve recovery and prevent further complications.
MilanAges 18 years+ - NCT06706674RecruitingPhase 3
Testing lumateperone for irritability in teens with autism
This study tests an investigational medication called lumateperone to see if it can reduce irritability in children and teens with autism. It is for teenagers aged 13–17 whose irritability is causing significant problems.
Little Rock, ArkansasAges 5–17 - NCT06712602RecruitingPhase 1
Testing PT150 for Alcohol Use Disorder
This study tests whether a drug called PT150 can help people with moderate to severe alcohol use disorder who are not currently seeking treatment. You will be asked to stay abstinent from alcohol for short periods and attend sessions to see how PT150 affects your body and alcohol cravings.
Lexington, KentuckyAges 21–55 - NCT04134923Recruiting
Brain PET scan study using a blood-flow and plaque tracer
This study uses PET/CT/MRI imaging to look for brain “imaging biomarkers” in people across the Alzheimer’s disease range. It may help researchers better understand how Alzheimer’s changes the brain over time and improve future treatments.
St Louis, MissouriAges 18 years+ - NCT05799001Recruiting
Dance workshops for seniors with dementia behavior changes
This trial tests whether structured dance sessions can help improve behavioral and emotional symptoms in people with dementia living in care facilities. It may help by offering a gentle, guided activity while keeping medications stable.
Craponne-sur-ArzonAges 65 years+ - NCT05800470Recruiting
Brain-training with light sensors to improve walking in Parkinson’s
This trial tests a “neurofeedback” training program using a special light-sensing cap (fNIRS) to help improve balance and walking in people with Parkinson’s disease. You may also do guided walking practice mentally (imagery training), and your ability to walk and balance will be measured.
Taipei, None SelectedAges 40–85 - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06710483Recruiting
Dental care help for youth with disabilities
This study aims to make dental visits easier for youth with intellectual or developmental disabilities. It tests a program to support both patients and their dental providers.
Boston, MassachusettsAges 12–18
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.