Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06706882Enrolling by invitation
Thinking and memory in women who have experienced partner violence
This study looks at how thinking skills like planning and memory are affected in women who have survived intimate partner violence. It may help explain how these experiences affect daily life and mental health.
Granada, GranadaAges 18–50 - NCT06713616RecruitingPhase 3
Esketamine vs. ketamine for hard-to-treat depression
This study compares the effectiveness of esketamine (Spravato) and another similar drug, ketamine, for adults with major depression that has not improved after trying at least two other antidepressants. It aims to find out which treatment works better.
Milford, ConnecticutAges 18 years+ - NCT06706453Enrolling by invitation
Sleep survey for medical trainees
This study asks medical trainees about their sleep patterns as part of an online survey. It aims to understand how on-call work and training roles affect sleep in healthcare staff.
LondonAges 18 years+ - NCT06705907Recruiting
Helping middle-schoolers with autism improve school and social skills
This study tests a program to help middle school students with autism who have trouble with organization, planning, and social skills. It aims to improve their academic and social functioning in school.
Cincinnati, OhioAges 10–15 - NCT06713109Enrolling by invitation
Breastfeeding help with motivational counseling
This study tests if motivational counseling can reduce breastfeeding problems and anxiety. It offers support to mothers who are having trouble breastfeeding.
Istanbul, tuzlaAges Any age - NCT06709027Enrolling by invitation
Mobile health program for depression in older adults
This study is testing a smartphone-based health program designed for older adults with depression. The program aims to help you manage your mood and track changes in thinking and memory using a mobile app.
Fuzhou, FujianAges 60 years+ - NCT06706232RecruitingPhase 2
Psilocybin for Depression and Suicidal Thoughts in Bipolar II
This trial tests if two doses of psilocybin, given under medical supervision, are safe and acceptable for people with Bipolar II disorder who have mild to moderate depression and certain suicidal thoughts. The goal is to see if it may help improve mood and reduce suicidal thinking.
Houston, TexasAges 25–70 - NCT06710483Recruiting
Dental care help for youth with disabilities
This study aims to make dental visits easier for youth with intellectual or developmental disabilities. It tests a program to support both patients and their dental providers.
Boston, MassachusettsAges 12–18 - NCT06709404Recruiting
Telehealth support for caregivers of HIPEC patients
This study tests a telehealth program to help caregivers manage distress and financial stress while caring for someone receiving a special surgery (CS+HIPEC). It aims to see if the program improves caregivers' well-being.
Winston-Salem, North CarolinaAges 18 years+ - NCT06712784Recruiting
Support for autistic patients during needle procedures
This trial tests a behavior support program to help autistic patients and their caregivers during needle-related hospital visits at Boston Medical Center. It aims to reduce challenging behaviors and make procedures easier for everyone involved.
Boston, MassachusettsAges 3 years+ - NCT06712914Recruiting
Brain stimulation study for hoarding disorder
This study tests a safe, non-invasive brain stimulation method to see if it can help people with hoarding disorder who haven't gotten better with usual treatments. The procedure does not require surgery and is done in a doctor's office.
Palo Alto, CaliforniaAges 18–70 - NCT06706544RecruitingPhase 2/Phase 3
Ozone treatment for numbness or tingling after chemo
This trial tests whether ozone treatment (a gas therapy) can help relieve numbness or tingling caused by chemotherapy. It is for people whose cancer is stable or in remission and who have had these nerve symptoms for at least 3 months.
Las Palmas, Las PalmasAges 18 years+ - NCT06297278Recruiting
Exercise and fear learning in teens
This study tests whether exercise can help teens learn to overcome fear more easily. It looks at how the brain and natural chemicals in the body respond during and after exercise.
Detroit, MichiganAges 14–17 - NCT03886025Recruiting
tDCS brain stimulation plus cognitive training and decision practice
This trial studies whether a noninvasive brain stimulation method (tDCS) combined with thinking and decision-making practice can improve how people perform on cognitive tasks. It is aimed at healthy adults, and it may help researchers understand who could benefit from these approaches.
Kingston, OntarioAges 18–40 - NCT05242393Recruiting
How daily body rhythms relate to recovery after stroke
This observational study looks at how your body’s daily rhythms may affect brain recovery after an ischemic stroke. It may help researchers understand what timing-related factors influence “neuroplasticity,” meaning the brain’s ability to adjust and heal.
Saint PetersburgAges 18–80 - NCT05247125RecruitingPhase 4
Testing light or melatonin to help brain recovery after stroke
This study looks at whether changing your sleep timing using light therapy or melatonin can improve “brain rewiring” after an ischemic stroke. It mainly focuses on people who arrive very soon after stroke symptoms and who also meet specific safety and sleep/medication requirements.
Saint PetersburgAges 18–80 - NCT06018285Recruiting
Reducing suicide risk in teens in primary care
This study tests a step-by-step approach to reduce suicide risk in teens who get primary care. It's designed to help teens and their families get the right support, from talking to a care manager to more intensive help if needed.
Akron, OhioAges 12–17 - NCT06147999Recruiting
Biophoton therapy for brain disorders
This trial tests a biophoton therapy, a light-based treatment, for people with brain disorders. It aims to see if this non-invasive approach can help improve symptoms.
Butler, PennsylvaniaAges 18 years+ - NCT06558409Recruiting
Safer Still: Firearm Safety for Families
This study helps parents of teens in mental health crisis make homes safer by addressing firearm storage. You'll get support tailored to your situation.
Columbus, OhioAges 18–90 - NCT06642181RecruitingPhase 1
Guanfacine and meditation with buprenorphine for opioid use disorder
This study tests if adding a medication called guanfacine and mindfulness meditation to standard buprenorphine treatment helps people with opioid use disorder. It looks at whether this combination can improve treatment outcomes and reduce opioid use.
Newark, New JerseyAges 18–55 - NCT06701903RecruitingPhase 2
Study of an investigational drug for generalized anxiety disorder
This study tests an investigational oral medication (ITI-1284) for people with moderate to severe generalized anxiety disorder (GAD) who haven't found enough relief from at least two standard medications. The goal is to see if this new drug helps reduce anxiety symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06696755RecruitingPhase 2
Study of icalcaprant for bipolar depression
This study tests an oral medication called icalcaprant for adults with bipolar I or II who are currently in a depressive episode. The goal is to see if it reduces symptoms and whether it's safe when taken alongside your usual mood stabilizer.
Huntsville, AlabamaAges 18–65 - NCT06703125Recruiting
Autism risk study for children born to mothers with HIV in Kenya
This study looks at how being born to a mother with HIV might affect a child's brain development and behavior. It will check for early signs of autism in children ages 2 to 6 years old.
EldoretAges 2–6 - NCT06700902Recruiting
Support program for college students with mental health challenges
This study tests a program called 'Taking Action' to help college students with serious mental illnesses manage their health and daily life. If you're a student with a mental health condition, you may be able to join to learn new coping skills through group education.
Philadelphia, PennsylvaniaAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.