Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1251
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease339
- Autism Spectrum Disorder240
- Dementia227
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder142
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Suicidal Ideation89
- Mild Cognitive Impairment (MCI)88
Leading sponsors
- VA Office of Research and Development105
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- The University of Hong Kong51
- Karolinska Institutet50
Where studies are running
- California520
- Massachusetts267
- New York256
- Texas209
- Maryland176
- Pennsylvania171
- Florida149
- Alabama118
- Arizona108
- Illinois104
Recruiting studies7,780 total
- NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06526208RecruitingPhase 2
Marijuana-based compound for anxiety in autistic adults
This study tests a marijuana-based compound (similar to CBD but not psychoactive) to see if it helps reduce anxiety in autistic adults. You would take a daily capsule and be monitored for 12 weeks.
Phoenix, ArizonaAges 18–45 - NCT06528158Recruiting
Speech groups for children with a sibling with anorexia
This study offers group speech therapy sessions for children whose sibling has anorexia nervosa. It helps them talk about their feelings and experiences in a supportive setting.
ToulouseAges 8–18 - NCT06524505Recruiting
Deep brain stimulation for bipolar depression
This trial tests a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) to see if it improves depression in people with bipolar disorder. dTMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
TianjinAges 18–65 - NCT06523296Recruiting
Antibodies and thinking problems in myasthenia or Alzheimer's
This study looks at whether certain antibodies are linked to memory and thinking problems in people with myasthenia gravis or Alzheimer's disease. It involves a one-time use of leftover spinal fluid from a previous diagnostic test.
Nice, Alpes MaritimesAges 18 years+ - NCT06526247Recruiting
Testing programs for intimate partner violence in Washington state
This study tests support programs for men who have been court-referred for intimate partner violence in Washington state. It also includes their partners to see how well the programs work.
Boston, MassachusettsAges 18 years+ - NCT06515236Enrolling by invitation
A study of depression treatment for teens from minority groups
This study is testing a new way to help teens (ages 12–18) from racial or ethnic minority groups who are feeling depressed. It looks at how working with a specially trained therapist can improve their mental health.
New Haven, ConnecticutAges 12 years+ - NCT06526143Recruiting
Pain care pathway for recent veterans
This study tests a new approach to help veterans manage pain in their back, neck, knee, or shoulder after leaving the military. It includes phone or online check-ins and support tailored to your needs.
West Haven, ConnecticutAges 18 years+ - NCT06521476RecruitingPhase 2
Acetazolamide for sleep apnea in people on opioid treatment
This trial tests if a drug called acetazolamide can help people with central sleep apnea who are also on medication for opioid use disorder. Sleep apnea causes breathing to stop during sleep, and this study aims to see if the drug improves their sleep breathing.
Pittsburgh, PennsylvaniaAges 18–100 - NCT06516575Recruiting
Listening effort in cochlear implant users
This study measures how much effort it takes to listen and understand speech for adults with cochlear implants compared to those with normal hearing. It can help researchers learn how to improve hearing outcomes.
Minneapolis, MinnesotaAges 18–75 - NCT06531135Enrolling by invitation
Counseling to help you adjust to breast cancer
This trial tests a counseling program to help people with breast cancer feel more positive and cope better. It's designed for newly diagnosed patients who can read and write Chinese.
TaipeiAges 20–70 - NCT06526078Recruiting
Combining brain training with ketamine for depression
This study tests if adding computer-based cognitive training to ketamine treatment can improve mood in people with depression that hasn't responded to other treatments. It aims to see if the combination works better than ketamine alone.
Oakland, CaliforniaAges 18–80 - NCT06524830RecruitingPhase 2
Testing VLS-01 film for treatment-resistant depression
This trial tests an experimental film placed inside the cheek (VLS-01) against a placebo to see if it helps people whose depression hasn't improved with standard antidepressants. If you have tried at least two antidepressants without success, this study may be an option for you.
Tucson, ArizonaAges 18–65 - NCT06514001RecruitingPhase 2
Testing a new drug for Alzheimer's disease with eye scans
This trial tests an investigational drug called AMDX-2011P for people with Alzheimer's disease. It looks at whether the drug affects the retina, which may be linked to brain changes in Alzheimer's.
Phoenix, ArizonaAges 18 years+ - NCT05290285Recruiting
Amino acids for anorexia nervosa, compared with placebo
This study tests whether taking certain amino acids can help people with anorexia nervosa. Participants are randomly assigned to amino acids or a placebo (a look-alike with no active ingredient) to see which works better.
Garda, ItalyAges 16–50 - NCT05901558Recruiting
Remote therapy program for toddlers with autism
This trial studies a structured remote (video/at-home) therapy plan for toddlers who have been screened as having autism. It may help improve toddler development and support families with regular follow-up.
Shanghai, Shanghai MunicipalityAges 1.3 years–2.5 years - NCT05316948Recruiting
Study of mental health and sexuality in teens
This study asks young people in psychiatric care about mental health and sexuality, using their study information to understand how these may relate. You may be able to join whether or not you take psychiatric (mental health) medicines, as long as it doesn’t interfere with urgent/emergency needs.
Vence, Alpes MaritimesAges 15 years+ - NCT06000774Recruiting
Therapeutic Ketogenic Diet for Anorexia Nervosa
This study tests whether a therapeutic ketogenic diet (a very low-carb, high-fat eating plan) can help people with anorexia nervosa, including those who have recently recovered their weight and those who are still underweight. The diet may help improve brain function and reduce eating disorder symptoms.
San Diego, CaliforniaAges 18–45 - NCT06123741Recruiting
Virtual reality for thinking skills in children with ADHD
This trial uses virtual reality games to help children with ADHD improve their thinking and planning skills. It is designed for children who already take ADHD medication and speak Finnish.
OuluAges 8–12 - NCT06236048Recruiting
Brain energy and glutamate in schizophrenia
This study uses brain scans (MRI and PET) to look at energy use and a brain chemical called glutamate in people with schizophrenia. It compares healthy volunteers to those with well-controlled schizophrenia and those with hard-to-treat schizophrenia to understand the biology better.
LondonAges 18–65 - NCT06416306RecruitingPhase 1
Speech therapy for bilingual children with speech sound errors
This study tests a speech therapy program for bilingual children (Spanish and English) who have trouble saying certain sounds. The goal is to find which treatment targets work best to help them speak more clearly.
Iowa City, IowaAges 3–8 - NCT06444256RecruitingPhase 2
Testing a sleep medication for people with stimulant use
This trial tests whether a medication that blocks a brain chemical involved in wakefulness can help people with stimulant use disorder sleep better. If you use cocaine or methamphetamine and have trouble sleeping, this study may be an option.
Houston, TexasAges 18–65 - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT06498128Recruiting
Pregnancy safety registry for insomnia drug QUVIVIQ
This registry follows pregnant women with insomnia who used or did not use the sleep medication QUVIVIQ. It aims to track pregnancy and baby outcomes to understand safety.
Durham, North CarolinaAges 15–50
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,430 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.