Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT06203899Recruiting
Depression and suicide prevention for teens in special schools
This study tests a program to prevent depression and suicide in teens at special schools. It helps if you've had some symptoms but aren't already getting treatment.
Boekel, Noordoost BrabantAges 12–18 - NCT06198023Recruiting
Improving social skills for anxiety and eating disorders
This study looks at whether a program focused on improving social skills can help people with anxiety or eating disorders. It’s for young adults ages 18–30 who have had these conditions in the past year but are currently stable.
Dallas, TexasAges 18–30 - NCT06201533Recruiting
Light exercise and thinking activities for memory
This study tests if a program that combines light physical activity with simple mental tasks can help improve memory and thinking in people with mild cognitive impairment (MCI). It is for people who are not already exercising regularly and do not take memory medications.
Chiang MaiAges 60 years+ - NCT06191198RecruitingPhase 2
Communication Bridge 3: Speech therapy for PPA
This study tests a web-based speech therapy program called Communication Bridge for people with Primary Progressive Aphasia (PPA) and their communication partners. The goal is to improve communication skills and quality of life.
Chicago, IllinoisAges 18–100 - NCT06192615RecruitingPhase 3
Can a sleep medication protect the brain after heart surgery?
This study tests whether a medicine called dexmedetomidine, given after heart surgery, can help prevent confusion and thinking problems in older adults during their intensive care stay. If you are 60 or older and having heart surgery with a heart-lung machine, this trial might be for you.
Los Angeles, CaliforniaAges 60 years+ - NCT05205291Recruiting
Imaging inflammation in Parkinson’s using PET/MR scans
This study uses special brain scans (PET/MR) to see inflammation in people with Parkinson’s disease or related conditions. It may help researchers better understand what drives symptoms and how inflammation changes in the brain.
ExeterAges 50–85 - NCT05591924Recruiting
Bioinformatics study in adults with very early severe ICU illness
This trial studies how early severe illness in the ICU can be understood and tracked using health data (bioinformatics/informatics). It may help improve care decisions for people who arrive to the ICU soon after an emergency department visit.
London, OntarioAges 18 years+ - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT05629871Recruiting
Tracking sleep changes in early Alzheimer’s and thinking decline
This study looks at how sleep and wake patterns change in people with early Alzheimer’s, and whether these changes relate to memory and thinking decline. You may be asked to do questionnaires, sleep diaries, and possibly a diagnostic spinal fluid test (lumbar puncture) to measure biomarkers.
MontpellierAges 50–85 - NCT06180681Recruiting
School team program for children with ADHD ages 7-11
This study tests a team-based approach in schools to help children with ADHD. It works with parents, teachers, and school mental health providers to improve the child's behavior and school success.
San Diego, CaliforniaAges 7–11 - NCT06180902Recruiting
Testing fluid response methods in patients with reduced consciousness
This trial compares different ways to check if a patient in the ICU with lowered consciousness needs more IV fluids. It aims to find the most accurate method, which could help doctors give the right amount of fluid.
MoscowAges 18 years+ - NCT06170047Recruiting
Parent program for foster and kinship caregivers
This study tests a parenting program designed to support foster and kinship caregivers in Ohio. It aims to help you build skills and confidence while caring for a foster child aged 2 to 8.
Cincinnati, OhioAges 2 years+ - NCT06178328Recruiting
Online mental health program for Canadian adults
This study is testing a short online mental health program for adults in Canada who are seeking help. It aims to see if the program helps people feel better.
Regina, SaskatchewanAges 18 years+ - NCT06164262Recruiting
Dementia risk study for people with small vessel disease
This study tracks people ages 30 to 60 who have signs of small vessel disease on brain MRI. It aims to understand the risk of dementia over the next 10 years, so you can get early monitoring and care.
Hangzhou, ZhejiangAges 30–85 - NCT06156293Recruiting
Preventing insomnia step-by-step in Chinese adults
This trial aims to prevent sleep problems from becoming serious by using a step-by-step approach that starts with low-cost, easy treatments and adds more help if needed. It is for Chinese adults who currently have only mild or no insomnia.
Hong KongAges 18–70 - NCT06179485Enrolling by invitation
Ketamine vs. Etomidate for emergency breathing tube: long-term study
This study compares how two common medicines (ketamine and etomidate) used during emergency breathing tube placement affect long-term recovery. It is only for patients already enrolled in another related trial.
Birmingham, AlabamaAges 18 years+ - NCT06173752Recruiting
How exposure therapy works for OCD
This study looks at how exposure therapy helps people with OCD. It aims to understand the mechanisms behind why this treatment is effective.
San Diego, CaliforniaAges 18–65 - NCT06158880Recruiting
Alcohol and men's sexual risk behaviors
This study looks at how alcohol affects men's decisions about sex, especially risky behaviors like not using condoms. If you join, you may help researchers understand how to reduce HIV and STI risk.
Phoenix, ArizonaAges 21–30 - NCT06162624Recruiting
Workbook to help with anxiety and depression in prison
This study is testing a special workbook that helps people in prison manage tough emotions like anxiety and depression using a technique called ACT (Acceptance and Commitment Therapy). The workbook is designed to be used on your own, and the study wants to see if it can help you feel better.
Madison, WisconsinAges 18 years+ - NCT06160284RecruitingPhase 1
Psilocybin for brain healing in opioid recovery
This study tests whether psilocybin, a psychedelic substance, can help change brain connections in people recovering from opioid use disorder. It involves brain scans and careful medical monitoring to explore new treatment options.
New Haven, ConnecticutAges 25–55 - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT06177990Recruiting
Online skills training for caregivers of people with Alzheimer's
This study tests an online program to help family caregivers develop navigation skills for supporting a loved one with Alzheimer's or related dementias. It aims to reduce caregiver stress and improve care coordination.
Atlanta, GeorgiaAges 18 years+ - NCT06155682Recruiting
TMS for Improving Self-Control in Schizophrenia
This trial tests whether a type of brain stimulation called TMS can help people with schizophrenia improve their ability to stop impulsive actions. By targeting the part of the brain that controls inhibition, researchers hope to reduce symptoms and improve daily functioning.
Catonsville, MarylandAges 18–45 - NCT06170970RecruitingPhase 2
Solriamfetol for fatigue in multiple sclerosis
This study tests whether solriamfetol, a medication that promotes wakefulness, can reduce fatigue in people with multiple sclerosis. If you struggle with tiredness and sleepiness, this trial may help you understand how this drug works for MS-related fatigue.
Baltimore, MarylandAges 18–60
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.