Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05795634Recruiting
Study stress effects in people at risk for Alzheimer’s
This study looks at how stress may affect thinking and memory in people with mild cognitive impairment (MCI) who are at risk for Alzheimer’s disease. You may be asked to do thinking tests and also involve a knowledgeable person who can report on changes over time.
Baltimore, MarylandAges 60 years+ - NCT05786157Recruiting
Couples alcohol and safety support for drinking and relationship harm
This study tests a patient-focused approach to help couples where alcohol misuse and relationship physical harm may be happening. You may be asked to take part in sessions focused on safety, coping, and relationship communication, and some components may include controlled alcohol exposure.
Charleston, South CarolinaAges 21 years+ - NCT05810636Enrolling by invitation
Activity tracking in children with ADHD
This study uses a smartwatch and smartphone to track the activity of children with and without ADHD. The goal is to understand how hyperactivity differs between groups.
TaipeiAges 6–18 - NCT05803343Recruiting
Testing added benefits of including dogs for autism emotion control
This study tests whether adding dogs to therapy or activities helps children with autism better manage strong emotions and reactions. It may help families who are concerned about emotion outbursts or difficulty regulating feelings.
Cincinnati, OhioAges 8–15 - NCT05806112Enrolling by invitation
Improve staff well-being programs for residential care workers
This trial tests whether specific programs can reduce burnout and improve resiliency (coping strength) among staff who work in behavioral health group homes. It may help workers feel better and handle stressful work days.
Boston, MassachusettsAges 18 years+ - NCT05778734Recruiting
Study to help young adults improve alcohol steadiness
This study is looking at ways to increase “alcohol abstinence,” meaning drinking less or stopping. It focuses on young adults who currently drink and have symptoms of alcohol use disorder, and it may help them build skills to reduce or stop drinking.
Chicago, IllinoisAges 18–24 - NCT05786066RecruitingPhase 2
Test whether blocking AMPA changes ketamine’s suicide relief
This study looks at whether an “AMPA receptor blocker” changes how ketamine affects suicidal thoughts in people with depression that hasn’t improved with usual treatments. If you qualify, you may receive ketamine and the study medicine, while continuing your regular mental health care.
West Haven, ConnecticutAges 21–65 - NCT05781009RecruitingPhase 2
Pregnenolone treatment for alcohol use disorder
This Phase 2 study tests pregnenolone to help reduce or improve alcohol use disorder symptoms. It looks for adults who drink regularly and meet diagnostic criteria for moderate to severe alcohol use disorder, while excluding people with certain other substance use, medicines, or serious mental/medical conditions.
New Haven, ConnecticutAges 18–70 - NCT05792930Recruiting
Therapy plus biofeedback for body-symptom distress
This study tests an integrated talk-therapy program that combines cognitive-behavioral therapy and biofeedback to help people whose symptoms are strongly felt in the body. It may help by teaching skills to reduce distress and improve how you manage symptoms.
YunlinAges 20–70 - NCT05789446Recruiting
Testing a coping and identity skills program for teens
This study tests whether a skills program helps children better cope and build a strong sense of identity. It is offered to early teens and may help with stress and emotional challenges.
Harrisburg, PennsylvaniaAges 11 years+ - NCT05780814Recruiting
Treating insomnia to improve weight loss after breast cancer
This study looks at whether improving insomnia (trouble falling asleep or staying asleep) can help survivors of breast cancer lose weight more successfully through a structured behavioral weight loss program. It may help if sleep problems are making it harder to change eating and activity habits.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05810259Recruiting
Digital wellness modules to improve quality of life
This study tests whether online “wellness” lessons help people feel better in everyday life and report a higher quality of life. It likely involves completing digital wellness modules and answering questionnaires to measure changes over time.
New Haven, ConnecticutAges 18–65 - NCT05807178Recruiting
Light treatment to stabilize sleep-wake rhythm in ICU delirium
This trial tests whether controlled bright light in the ICU can improve confusion and the sleep-wake rhythm in adults who develop delirium. If it works, it may help patients become more clear-minded sooner while they recover in intensive care.
BerlinAges 18 years+ - NCT05783817RecruitingPhase 2
MDMA-assisted therapy for OCD in adults
This trial tests whether MDMA plus cognitive behavioral therapy (CBT) can reduce OCD symptoms in adults who have tried standard OCD treatments before. You may be asked to pause certain medicines and follow specific diet/medication rules around the study session.
Palo Alto, CaliforniaAges 18 years+ - NCT05782829Recruiting
L-tyrosine to reduce stress during outpatient hernia surgery
This trial studies whether an L-tyrosine supplement before surgery can reduce stress or anxiety around the time of anesthesia and recovery. It is for adults having outpatient surgery for an inguinal hernia under general anesthesia.
MonacoAges 18–75 - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85 - NCT05800639Recruiting
Testing brain-wave patterns during pediatric anesthesia awakening
This study looks at brain-wave activity (measured with sensors) in young children during and after general anesthesia for planned eye surgery. It may help doctors understand why some children become very upset or confused as they wake up.
SeoulAges 2–8 - NCT05809115Recruiting
Caregiver-child bonding support for hospitalized young children
This study looks at how a caregiver and their young child bond during a hospital stay, and whether extra support can help. It may help families feel more connected and supported while their child is in the hospital.
Houston, TexasAges 18 years+ - NCT05800509Recruiting
Program for gestational diabetes and low mood in pregnancy
This study offers an intervention program to help people who are diagnosed with gestational diabetes and may also experience depression during pregnancy. It may help improve health during pregnancy and support mood and well-being with smartphone-based participation.
TaipeiAges 20 years+ - NCT05790668Recruiting
Motivation tips to reduce frequent rewards for destructive behavior
This trial tests behavior-support strategies that may help gradually reduce how often a child’s destructive behavior gets reinforced. It’s aimed at children with frequent destructive behavior that continues even with past treatment.
New Brunswick, New JerseyAges 3–17 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT05778591RecruitingPhase 2
Low-dose buprenorphine to improve social drive in schizophrenia
This study tests whether low-dose buprenorphine can improve social motivation in people with schizophrenia. It compares social motivation changes while keeping participants stable on treatment and avoiding certain medicines and substances.
Los Angeles, CaliforniaAges 18–60 - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05317390Recruiting
Tests an AI tool to diagnose isolated dystonia
This trial checks whether an AI (software) called DystoniaNet can accurately identify isolated dystonia using information from your evaluation, and compares its results to standard diagnosis. If you have focal, segmental, or generalized dystonia, this study may help improve faster and more accurate diagnosis in the future.
Boston, MassachusettsAges Any age
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
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- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.