Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT04943562Recruiting
Testing sleep sensors to score your sleep stages
This study checks whether wearable sensors (like a sleep band and a wearable EEG) and a phone can accurately identify your sleep stages. It includes healthy people and people with sleep problems to see how well the devices work and whether results match a standard sleep lab test.
São Caetano do Sul, São PauloAges 20–80 - NCT05734768Recruiting
Study of anxiety and depression in parents after preterm birth
This study compares how parents feel (anxiety and depression symptoms) after having a baby born preterm versus a full-term baby. It also looks at early “building blocks” of thinking and social development in the child.
ReimsAges 18 years+ - NCT05776056RecruitingPhase 4
Methylphenidate for PTSD with memory and thinking problems
This study tests whether methylphenidate, a medication commonly used for attention issues, can help veterans with PTSD who also have memory or concentration problems. The goal is to see if it improves these cognitive symptoms.
Birmingham, AlabamaAges 18–65 - NCT05770479Enrolling by invitation
Testing long-lasting cognitive training for older veterans
This study looks at whether a cognitive training program you’ve already completed can keep helping over time, and whether it can be improved with “booster” sessions. It may help older veterans maintain thinking and daily functioning skills after earlier training.
San Diego, CaliforniaAges 55 years+ - NCT04080778Recruiting
Magnetic seizure treatment for severe bipolar or hard-to-treat depression
This trial studies whether a seizure-like therapy using magnet stimulation can quickly reduce severe depressive symptoms in people with bipolar depression or treatment-resistant depression. It may help when depression is intense and hasn’t improved enough with at least two antidepressant medicines.
Houston, TexasAges 22–85 - NCT05754073RecruitingPhase 2
Oxytocin to improve bone health in children with autism
This Phase 2 study tests whether oxytocin can help improve bone health in children and teens with autism spectrum disorder. It also checks safety by monitoring symptoms and doing blood tests and imaging.
Boston, MassachusettsAges 6–18 - NCT05765656Recruiting
Doctors and pharmacists helping older adults reduce sleeping pills
This study will see if working closely with your doctor and pharmacist can help older adults safely reduce or stop taking medications for anxiety or sleep, like benzodiazepines.
NantesAges 65 years+ - NCT05766592RecruitingPhase 3
Therapy for sexual or gender-minority adults and a rejecting parent
This study tests a therapy program tailored for sexual and gender-minority adults who are dealing with strong rejection from a parent. It also involves that parent in sessions to help improve support and reduce anxiety or depression.
New York, New YorkAges 20 years+ - NCT05754567Recruiting
Study brain and development outcomes in CONCEPTT kids
This study looks at children’s neurodevelopment (how the brain, learning, and development are going) whose mothers took part in the earlier CONCEPTT trial. It may help researchers understand how having type 1 diabetes in pregnancy can relate to a child’s development.
Calgary, AlbertaAges 6 years+ - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT05773755Recruiting
Brain stimulation surgery for treatment-resistant depression
This trial studies whether deep brain stimulation (DBS)—a surgically placed brain device—can reduce severe, long-lasting depression that hasn’t responded to many treatments. It may help people whose depression has persisted despite trying multiple antidepressant and other evidence-based therapies.
New York, New YorkAges 25–70 - NCT05776641Recruiting
Light and sound training to help prevent Alzheimer’s memory loss
This study tests whether regular “gamma” light and sound stimulation can delay or prevent Alzheimer’s disease-related memory decline in people who are currently not showing dementia but are at higher risk. It uses brain testing (MRI and PET) and memory/language tests over about 13 months.
Boston, MassachusettsAges 55–90 - NCT05758987Recruiting
Online therapy for PTSD using a computer program
This trial studies a new blended, computer-assisted version of trauma-focused cognitive behavioral therapy for people with PTSD. It may help reduce PTSD symptoms by delivering structured therapy using a computer and online sessions.
StockholmAges 18 years+ - NCT05754151Recruiting
Mobile therapy for anxiety and depression in adults 40+
This trial tests whether a phone or tablet version of cognitive behavioral therapy (CBT) can help people ages 40 and older with anxiety or depression. It may help you manage symptoms with skills you can use between sessions.
New York, New YorkAges 40 years+ - NCT05748613Recruiting
Anxiety-focused skills training for people with Alzheimer’s
This study tests a treatment aimed at reducing anxiety in people who have Alzheimer’s disease or related memory problems. It also involves a support partner, and the goal is to see whether the program can lower anxiety and stress day-to-day.
Tallahassee, FloridaAges 60 years+ - NCT05774002Recruiting
Psychological check-in for teens getting back surgery for scoliosis
This study asks teens with idiopathic scoliosis to complete psychological assessments while planning for elective back surgery. It may help doctors better understand patients’ mental and emotional needs around surgery.
The Bronx, New YorkAges 10–19 - NCT05750095Recruiting
Parenting support program for children with autism
This trial tests parenting programs designed for parents of young children with autism (ages 2–6). It may help you learn practical ways to support your child and your family day to day.
BergenAges 2–6 - NCT05763849Recruiting
Therapy exposure for teens with low weight eating issues
This trial tests a structured therapy approach called “interoceptive exposure” for teens who have an eating disorder with low weight. It may help some teens reduce fear or avoidance around body sensations and improve eating, but you must meet several health and safety criteria.
New York, New YorkAges 12–18 - NCT05754840RecruitingPhase 1/Phase 2
Cannabinoid treatment for children with hard-to-treat cancers
This early-phase study tests whether a cannabinoid medicine (including nabilone/cannabis-based treatment) can be given safely to children and teens with relapsed or refractory cancer. It may help with treatment options for children whose cancer has come back or did not respond to standard therapy.
Vancouver, British ColumbiaAges 4–18 - NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Gibbsboro, New JerseyAges 12–18 - NCT05746572Enrolling by invitationPhase 2
MDMA-assisted therapy plus exposure therapy for PTSD
This Phase 2 study tests whether MDMA combined with therapy that uses exposure (gradual confronting of trauma memories) can reduce PTSD symptoms. It may help people who meet PTSD criteria, can follow strict safety rules, and can complete medicine-session monitoring.
Atlanta, GeorgiaAges 21–70 - NCT05746767Enrolling by invitation
Spanish digital therapy coaching for depression and anxiety
This study tests a digital “cognitive behavioral therapy” program with peer support to help Spanish-speaking adults with depression or anxiety. It may help you manage symptoms using structured online tools and guided peer interaction.
Payson, ArizonaAges 18 years+ - NCT05762796Recruiting
Brain scan and stimulation study for kids with mild concussion
This study tests whether a brain “stimulation” approach, paired with brain imaging (MRI), can help children who still have symptoms after a mild concussion. There is also a comparison group of children without concussion history.
Buffalo, New YorkAges 10–15 - NCT05766553Recruiting
Virtual reality mindfulness to reduce cigarette cravings
This trial tests whether guided mindfulness meditation in virtual reality can lower cigarette cravings and help people quit smoking. It may help by reducing urges to smoke during stressful moments.
IteuilAges 18–75
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.