Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT04712461Recruiting
Support program to reduce therapist burnout
This trial tests whether adding specific implementation supports can reduce burnout in therapists who provide evidence-based care for children who have experienced trauma. It may help therapists feel more supported while delivering these child trauma treatments.
San Diego, CaliforniaAges 3–99 - NCT04704271RecruitingPhase 1
Study on THC effects in people with past cannabis use
This Phase 1 study looks at how THC (the main mind-altering ingredient in cannabis) affects healthy volunteers shortly after use. It focuses on differences between people and includes those who have used cannabis before.
West Haven, ConnecticutAges 18–55 - NCT04732052Recruiting
tDCS treatment for adults with developmental disabilities and aggression
This trial tests whether a non-painful brain stimulation treatment (tDCS) can reduce aggressive behaviors in adults with developmental disabilities. It’s meant for people who have had aggression in the last month and can safely receive the stimulation.
Kingston, OntarioAges 18–65 - NCT04745143RecruitingPhase 2
NMDA-enhancer medicine tested for schizophrenia without antipsychotics
This Phase 2 trial tests a single medicine intended to help people with schizophrenia who cannot take standard antipsychotic medications due to side effects or poor response. It may help reduce schizophrenia symptoms, but whether you can join depends on your diagnosis, medication history, and health conditions.
TaichungAges 18–65 - NCT04706910RecruitingPhase 3
PET scan study to optimize imaging in several diseases
This trial improves a special PET scan (a type of brain/body imaging) using 18F-DOPA, to better show how certain conditions behave in the body. If you or your child may have one of the listed conditions, the study may help your doctors get clearer scan results.
Edmonton, AlbertaAges Any age - NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT04763343RecruitingPhase 3
Ketamine to help prevent repeat suicide attempts in youth
This Phase 3 study tests ketamine to reduce ongoing suicidal thoughts and help prevent another suicide attempt in youth after a recent attempt. It will compare ketamine treatment against standard care to see if it helps improve safety and reduce suicide risk.
Cleveland, OhioAges 14–30 - NCT04685486Recruiting
Virtual reality program to help burn pain
This trial tests whether virtual reality (immersive computer experiences) can help manage pain in people with burn injuries. It’s for burn patients who can safely participate without heavy sedation or certain mental health or substance-use issues.
New York, New YorkAges 8 years+ - NCT04697966Recruiting
Smartphone mindfulness program for teens and what predicts improvement
This study tests an app-based mindfulness training program for adolescents ages 13–18 and looks at what helps predict which teens improve. It may be helpful if you’re looking for a structured mindfulness practice and want to understand what changes in your thinking and feelings over time.
Belmont, MassachusettsAges 13–18 - NCT04752618Recruiting
Support program for mothers with trauma and young children
This study offers a structured support program for mothers dealing with trauma symptoms like PTSD, aiming to improve wellbeing and support parenting. It also involves clinicians connected to the Safe Mothers, Safe Children program.
New York, New YorkAges 18 years+ - NCT04725409Recruiting
Study brain signals during psychiatric evaluations with SEEG
This study looks at brain activity to better understand psychiatric disorders. You may be able to join if you are already having a specific brain-monitoring procedure at Vanderbilt and can complete questionnaires.
Nashville, TennesseeAges 18 years+ - NCT04770584Recruiting
Fear and avoidance study in PTSD and healthy volunteers
This study looks at how people with current PTSD—or people without PTSD—respond to fear and avoiding things they might find threatening. It may help researchers understand these patterns and how they differ after trauma.
Houston, TexasAges 18–70 - NCT04707794Recruiting
Preventing confusion after non-heart surgery in older adults
This study looks at how often older adults develop sudden confusion (delirium) after non-heart operations under general anesthesia. It may help doctors better predict who is at risk and improve care after surgery.
New Delhi, National Capital Territory of DelhiAges 65 years+ - NCT04715399Recruiting
Research study collecting data for neurodegenerative diseases
This study collects health information from people with neurodegenerative diseases, some family members, and healthy controls to help researchers better understand these conditions. It may help future diagnosis and research, and participation may include noninvasive checks and other procedures depending on your situation.
Philadelphia, PennsylvaniaAges 18 years+ - NCT03799991Recruiting
Balance therapy for people with early-to-moderate Alzheimer’s
This trial tests whether an 8-week balance and movement program can help people with early-to-moderate Alzheimer’s who also have inner-ear (vestibular) balance loss. You and a caregiver may learn exercises and attend weekly visits, while researchers compare the results to an active control program.
Baltimore, MarylandAges 60 years+ - NCT04647656Recruiting
Hyperbaric oxygen for lingering post-COVID brain fog
This study tests whether breathing pure oxygen in a pressurized chamber (hyperbaric oxygen therapy) can improve long-lasting post-COVID problems with thinking and memory. It may help if your brain symptoms have lasted at least 3 months and affect your daily life.
ẔerifinAges 18 years+ - NCT04638452Recruiting
Study of reactions during routine blood tests in autism
This study looks at how people with autism (and some without autism) react during a routine blood test. Researchers will watch and measure behavior and body responses to better understand distress and comfort during needle procedures.
BordeauxAges 6–65 - NCT04631042Recruiting
Study how the brain relates to impulsivity and compulsivity
This study looks at how brain function and structure relate to impulsive and compulsive behaviors. It may help researchers understand what drives these behaviors and who may benefit from future mental health treatments.
Bethesda, MarylandAges 6–80 - NCT04635657Recruiting
Testing brain function after meningioma surgery
This study measures how thinking and memory change after surgery to remove a meningioma near the front or side of the brain. It may help doctors better understand what to expect and how cognitive recovery can differ from person to person.
Columbus, OhioAges 18–89 - NCT04639622Recruiting
Study for inherited frontotemporal dementia gene risks
This study recruits adults who come from families with certain known gene changes linked to frontotemporal dementia. It aims to learn more about these inherited forms of dementia using brain scans and research blood testing, which will not provide personal results.
LilleAges 18 years+ - NCT04626050Recruiting
PTSD and stress support study for healthcare workers
This study looks at psychological distress, including post-traumatic stress disorder (PTSD), in healthcare workers after work-related trauma. You may be eligible if you are an adult healthcare worker with PTSD (and otherwise stable) who can complete regular study check-ins.
New York, New YorkAges 18 years+ - NCT04661280RecruitingPhase 3
Donepezil compared with non-drug care for Alzheimer’s
This trial compares donepezil (a medicine for Alzheimer’s symptoms) against a non-drug treatment plan. It aims to see which approach helps people with Alzheimer’s who still have measurable thinking ability and specific Alzheimer’s test results.
ParisAges 50 years+ - NCT04682223Recruiting
Online speech therapy for people with stroke-related aphasia
This study tests whether telerehabilitation (therapy done by video/remote technology) can improve communication after a stroke caused aphasia. It may help you practice speech and understanding skills at home or from a convenient location.
Columbia, South CarolinaAges 21–80 - NCT04649892RecruitingPhase 2
Using eye tracking to predict naltrexone response for gaming disorder
This trial tests if a medication called naltrexone can help people with video game disorder. It also uses eye tracking to see who might respond best to the treatment. If you feel a strong urge to play games and have specific symptoms like withdrawal or conflict, you might be eligible.
São Paulo, São PauloAges 18–60
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.