Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,780 recruiting studies in this area right now.
By phase
- Not applicable6,423
- Phase 2492
- Phase 1249
- Phase 3240
- Phase 4213
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress118
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,780 total
- NCT04669457Enrolling by invitationPhase 4
Study of delirium risk in young children having ear surgery
This trial looks at confusion or “delirium” after anesthesia in babies and young children having a myringotomy (ear procedure). It may help doctors understand which children are more likely to experience delirium and how to reduce that risk.
Worcester, MassachusettsAges 3 months–9 years - NCT04634175Enrolling by invitation
Yoga program for compulsive sexual behavior
This trial studies whether a 12-week yoga program can reduce compulsive sexual behavior and anxiety. It is offered to a specific group of participants in Brazil and focuses on daily mind-body practice.
São Paulo, São PauloAges 18 years+ - NCT04635657Recruiting
Testing brain function after meningioma surgery
This study measures how thinking and memory change after surgery to remove a meningioma near the front or side of the brain. It may help doctors better understand what to expect and how cognitive recovery can differ from person to person.
Columbus, OhioAges 18–89 - NCT04626050Recruiting
PTSD and stress support study for healthcare workers
This study looks at psychological distress, including post-traumatic stress disorder (PTSD), in healthcare workers after work-related trauma. You may be eligible if you are an adult healthcare worker with PTSD (and otherwise stable) who can complete regular study check-ins.
New York, New YorkAges 18 years+ - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT04624126Recruiting
3D-Printed external device study for erectile dysfunction
This study tests an external device to help men with moderate-to-severe erectile dysfunction (trouble getting/keeping an erection). You may be able to join if you’re 18 or older, have a willing female partner, and can try vaginal intercourse with the device as instructed.
Stanford, CaliforniaAges 18 years+ - NCT04649892RecruitingPhase 2
Using eye tracking to predict naltrexone response for gaming disorder
This trial tests if a medication called naltrexone can help people with video game disorder. It also uses eye tracking to see who might respond best to the treatment. If you feel a strong urge to play games and have specific symptoms like withdrawal or conflict, you might be eligible.
São Paulo, São PauloAges 18–60 - NCT04682223Recruiting
Online speech therapy for people with stroke-related aphasia
This study tests whether telerehabilitation (therapy done by video/remote technology) can improve communication after a stroke caused aphasia. It may help you practice speech and understanding skills at home or from a convenient location.
Columbia, South CarolinaAges 21–80 - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT04599270Recruiting
Preventing risky drinking in vulnerable teens
This study tests a program meant to reduce addictive behaviors in teens who may be at higher risk. It uses online activities and support, and it may help you build safer habits before problems grow.
BrestAges 14–17 - NCT04619836Enrolling by invitation
Study of diabetes care plans and cost-effectiveness
This trial looks at how well a diabetes care plan works and how cost-effective it is for people with type 2 diabetes. You may be included if your diabetes care and self-management are arranged using a specific care-planning approach.
TampereAges 18–90 - NCT04672551Recruiting
EMDR therapy for PTSD after a heart attack
This trial studies whether EMDR (a structured therapy that helps process distressing memories) can reduce PTSD symptoms in people who developed PTSD after a cardiac event. It may help you feel less overwhelmed by memories and stress related to the heart event.
ZurichAges 18–70 - NCT04633603Enrolling by invitation
Study of attitudes toward fever and fever care changes
This study looks at how people think about fever and how fever care works in the healthcare system. You may be asked to record details of fever episodes at home or in outpatient care to help researchers understand real-world fever management.
PécsAges Up to 100 years - NCT04629547RecruitingPhase 2
Sleep study to help prevent Alzheimer’s disease
This trial tests whether treating sleep issues and measuring sleep can help lower the risk of Alzheimer’s disease before it starts. It focuses on older adults with no dementia signs yet.
St Louis, MissouriAges 65 years+ - NCT04616781RecruitingPhase 2/Phase 3
Ketone drink study for alcohol use disorder brain function
This study tests whether a ketone-based treatment (a ketone ester) can change brain activity in people with alcohol use disorder who are not currently seeking treatment. You may also have brain scans, so the study is looking for safe MRI eligibility and certain health factors.
Philadelphia, PennsylvaniaAges 21–65 - NCT04519229Enrolling by invitation
Feasibility study of child-parent therapy for foster infants and toddlers
This study tests whether a therapy program called Child-Parent Psychotherapy is practical and helpful for very young children in foster care and the adults caring for them. It’s mainly a “feasibility” study, meaning it focuses on whether the program can be delivered and followed in real life.
VaxjoAges birth–6 years - NCT04582916RecruitingPhase 1
PET scan study of inflammation in major depression
This Phase 1 study uses a PET brain scan to look at inflammation-related activity (cyclooxygenase) in people with major depressive disorder (MDD). It may help researchers better understand how depression is connected to inflammation in the brain.
Bethesda, MarylandAges 18–70 - NCT04580134RecruitingPhase 4
Clozapine study for people with a specific schizophrenia or bipolar type
This trial tests whether clozapine works better for people whose illness fits a specific “biotype-1” pattern. It may help reduce ongoing symptoms, but it also requires close safety monitoring.
Hartford, ConnecticutAges 18–60 - NCT04557891Recruiting
Low-intensity ultrasound for generalized anxiety disorder
This trial tests a non-drug brain treatment using low-intensity focused ultrasound to reduce symptoms of generalized anxiety disorder (GAD). It may help if your anxiety has been moderate to severe and you’ve already tried standard medications without enough relief.
Los Angeles, CaliforniaAges 18–65 - NCT04588285RecruitingPhase 2
Ambroxol for new and early dementia with Lewy bodies
This trial tests whether ambroxol (a mouth medicine) can help people with new or early dementia with Lewy bodies (DLB) or mild cognitive impairment linked to DLB. Participants take the medicine for about 18 months while the study tracks safety and changes over time.
Haugesund, HaugesundAges 50–85 - NCT04550377RecruitingPhase 2
Cannabidiol for PTSD, including PTSD after mild head injury
This Phase 2 study tests whether cannabidiol (CBD) can reduce PTSD symptoms, including in people who also had a mild traumatic brain injury (TBI). It’s meant to see if CBD is helpful and safe for PTSD symptoms over the study period.
New York, New YorkAges 18–70 - NCT04529031Recruiting
Study of reminder-based positive thinking for teens with PTSD
This study looks at whether a “reminder-focused positive thinking” approach can help teens with PTSD. It may benefit you by testing how certain cues and supportive thoughts affect PTSD symptoms and related wellbeing.
Los Angeles, CaliforniaAges 11–15 - NCT04579120Recruiting
Brain scan study in healthy aging or early Alzheimer’s
This study uses brain imaging to understand changes in the brain during normal aging and early Alzheimer’s disease (AD). It may help researchers spot early brain changes and evaluate how well imaging measures those changes.
St Louis, MissouriAges 18 years+ - NCT04570085RecruitingPhase 3
Caffeine treatment to improve thinking in Alzheimer’s disease
This trial tests whether changing caffeine intake can improve thinking and brain function in people with Alzheimer’s disease. You may qualify if you can follow a low-caffeine diet and have stable Alzheimer’s treatment and sleep/heart conditions.
AmiensAges 50 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,780 recruiting psychiatry studies from the U.S. registry right now, out of 12,464 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.