Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,784 recruiting studies in this area right now.
By phase
- Not applicable6,423
- Phase 2495
- Phase 1249
- Phase 3240
- Phase 4214
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety388
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress118
- PTSD104
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development102
- Yale University87
- Massachusetts General Hospital79
- Stanford University69
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts269
- New York254
- Texas209
- Maryland175
- Pennsylvania170
- Florida148
- Alabama119
- Arizona111
- Ohio104
Recruiting studies7,784 total
- NCT04323566Enrolling by invitationPhase 2
Rituximab for OCD or psychosis linked to immune inflammation
This trial tests rituximab (an immune system medicine) to see if it can reduce OCD symptoms and/or psychosis when there are signs the immune system may be involved. You may be considered if other standard psychiatric treatments have not helped enough and your illness seems relatively recent with possible inflammation clues.
UppsalaAges 18–55 - NCT04354077Recruiting
Deep brain stimulation for opioid addiction
This study tests whether deep brain stimulation (DBS), a surgical treatment that uses electrical pulses to target specific brain areas, can help reduce cravings and relapse in people with opioid use disorder who haven't found relief from other treatments.
Pittsburgh, PennsylvaniaAges 22–65 - NCT04299893RecruitingPhase 2/Phase 3
Ozone treatment for chemotherapy nerve pain
This trial tests whether ozone therapy can reduce painful nerve damage caused by chemotherapy. It is for adults with ongoing moderate-to-severe pain in the hands or feet after chemotherapy.
Las Palmas de Gran Canaria, Las PalmasAges 18–100 - NCT04370730Recruiting
Study brain and symptoms in youth with early psychosis
This study looks at how psychosis symptoms and development change over time in children and teens. It may help doctors better understand different patterns of illness and how to support young people with these disorders.
GentillyAges 7–20 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Birmingham, AlabamaAges 18 years+ - NCT04322734Recruiting
Blood tests study immune and metabolism markers in neurodevelopment
This study looks for biological “signals” in blood—related to the immune system and metabolism—to better understand conditions like autism and other brain or development-related disorders. It may help researchers find markers that could guide future diagnosis or treatment.
Phoenix, ArizonaAges Up to 18 years - NCT04355195Recruiting
Preventing delirium after surgery in older patients
This trial tests a “care plan” meant to lower the risk of confusion (delirium) after surgery in people age 70 and older. If you qualify, you may receive additional prevention-focused care before and around your operation.
BerlinAges 70 years+ - NCT04335487Recruiting
Online therapy program for PTSD symptoms in public safety workers
This study tests an internet-based cognitive-behavioral therapy (an online talk-therapy style program that helps you manage thoughts and feelings) to reduce PTSD symptoms in public safety personnel. You may be able to join if you have PTSD-like symptoms and can safely take part in online treatment.
Regina, SaskatchewanAges 18 years+ - NCT04278898RecruitingPhase 2
N-acetylcysteine to reduce repetitive behaviors in children with autism
This Phase 2 study tests whether a single dose of N-acetylcysteine can improve “restricted and repetitive behaviors” in children with autism. It’s meant for kids who are stable and still in early puberty stages.
Stanford, CaliforniaAges 3–12 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Birmingham, AlabamaAges 75 years+ - NCT04356274Enrolling by invitation
Improving access to addiction and mental health care at VA clinics
This study tests an approach to help VA clinics reach more Veterans with proven treatments for addiction and mental health conditions. It focuses on clinic-level processes (not individual medications) to increase how widely evidence-based care is delivered.
Palo Alto, CaliforniaAges 18 years+ - NCT04267003Recruiting
Brain stimulation study for thinking and brain chemistry in schizophrenia
This study tests whether a brain stimulation approach can improve thinking (cognition) in people with schizophrenia and how it changes brain electrical signals and a brain chemical called GABA. It may help researchers understand new ways to support thinking and symptoms.
Sacramento, CaliforniaAges 18–47 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT04279158Recruiting
Attention training after stroke or for ADHD
This study tests an attention-focused training approach to help people improve how the brain inhibits or filters information. It may be relevant after certain stroke-related attention problems, and also for people with ADHD, or for healthy volunteers for comparison.
BronAges 8–75 - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT04351958Enrolling by invitation
AR videogame to prevent alcohol use in teens
This trial tests whether an augmented-reality (AR) videogame can help teens avoid drinking and reduce harm from alcohol. If you’re 16–18 and in high school, you may be asked to play the AR game during short sessions to see how well it works.
New Haven, ConnecticutAges 16–18 - NCT04150198Recruiting
PET-MR brain scan study of resilience in Alzheimer’s
This study uses a combined PET and MRI brain scan to understand why some people with Alzheimer’s (and related “focal” types) may cope better than expected. It may help researchers find brain patterns linked to resilience and to different Alzheimer’s subtypes.
OrsayAges 40–80 - NCT04165460Enrolling by invitation
CBT programs for anxiety and coping in cervical cancer
This study tests two structured talk-therapy programs (cognitive-behavioral therapy) to help people with cervical cancer manage anxiety, depression symptoms, and unhelpful coping skills. It also looks at the role of a main caregiver during care planning and support.
Mexico City, TlalpanAges 18 years+ - NCT04165746Recruiting
Early care program for very young children in foster systems
This study looks at how an early support program affects the development of infants who are newly entering institutional care or foster care in the São Paulo area. It may help families and caregivers support healthy growth during a critical first period.
São Paulo, São PauloAges Up to 2 years - NCT04153838Enrolling by invitation
Track thinking skills in children over time
This study follows children’s thinking and learning over time using simple testing at school. It aims to better estimate how children’s thinking develops and how it changes as they grow.
Aberdeen, UKAges 6–17 - NCT04163081Recruiting
Help to quit smoking started from the emergency department
This study tests a program to help people who smoke quit, beginning when they are seen in the emergency department. It aims to see if starting nicotine-cessation support right away improves quitting over the next year.
Ottawa, OntarioAges 18 years+ - NCT04159662Recruiting
Brain scans to study thinking in schizophrenia and depression
This study uses brain imaging to better understand how thinking works in people with schizophrenia or major depression. Your results may help researchers learn what brain patterns match different thinking and symptoms.
Ottawa, OntarioAges 18–60 - NCT04239079Recruiting
Study of immune-related changes in Parkinson’s and Alzheimer’s
This study looks for “autoimmune-like” (immune-system) features in brain-related diseases such as Parkinson’s and Alzheimer’s, using genetic testing and other assessments. Results may help researchers understand what drives these conditions and who might be more likely to have immune-related changes.
New York, New YorkAges 55–90 - NCT04226898RecruitingPhase 2
Synbiotic supplement to lessen schizophrenia symptoms
This Phase 2 trial tests whether a “synbiotic” supplement (a mix of probiotics and prebiotics) can reduce symptoms of schizophrenia or schizoaffective disorder. It may help by targeting gut-related immune and inflammation pathways that could affect brain symptoms.
Batlimore, MarylandAges 18–65
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,784 recruiting psychiatry studies from the U.S. registry right now, out of 12,489 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.