Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT05974553Recruiting
Dialectical behavior therapy for justice-involved veterans
This study tests whether dialectical behavior therapy (DBT, a structured therapy skills program) can help veterans with stress or behavior challenges related to justice system involvement. It may help by teaching practical coping skills in a group setting.
Aurora, ColoradoAges 18 years+ - NCT06035705Recruiting
Patient needs in hospital care
This study looks at how nurses assess how sick their patients are. It aims to improve care in medical wards.
GävleAges Any age - NCT05945199Recruiting
Brain stimulation to reduce cravings in chemsex users
This trial tests a non-painful brain stimulation method (tDCS) to help reduce cravings related to chemsex. If you qualify, you’ll be randomly assigned to real stimulation or a sham (placebo) and complete study visits and questionnaires.
DijonAges 18 years+ - NCT05973461Recruiting
Exercise and virtual reality study for depression
This study looks at whether doing regular exercise and using virtual reality can help with depression symptoms, compared to not doing them. You may be included even if you do not currently have depression symptoms, as long as you meet the safety and participation requirements.
Arlington, TexasAges 18–65 - NCT05933850Recruiting
Family program to improve parenting skills for caregivers
This trial tests a culturally adapted family support program aimed at improving parenting and family relationships for primary caregivers of children ages 8–15. If you qualify, you may receive structured sessions designed for families in Gilgit Baltistan, and outcomes will be tracked over the study period.
KarachiAges 18 years+ - NCT06067165Recruiting
Online emotion-regulation program for teens
This trial tests an online program called POET that helps teens learn skills to manage emotions. The program includes a parent part, so a guardian will also be involved. It may be a good option if you are between 12 and 17, have mild to moderate mental health struggles, and are not already in another treatment.
StockholmAges 12–17 - NCT05958654Recruiting
Screening for risk of readmission during home care visits
This study tests a universal “screening” approach during home-based primary care visits to spot which patients may be at higher risk of problems that could require urgent care or hospital return. It may help patients and their care team catch risks earlier and adjust care sooner.
Birmingham, AlabamaAges 18 years+ - NCT05974176Recruiting
Study on stress, trauma symptoms, and family support
This study looks at how racial and cultural stress may affect trauma-related emotional reactions in children and their parents/guardians. It may help researchers understand what kinds of support work best for families dealing with trauma.
New York, New YorkAges 5–17 - NCT06058455Recruiting
Online sexual assault resistance program for college women
This trial tests an online program to help first- and second-year college women resist sexual assault. It aims to empower you with skills and support from peers.
Orlando, FloridaAges 17–24 - NCT05921201Recruiting
RRE program to prevent depression in Chinese American teens
This trial tests an education and skills program (Relax, Reflect, and Empower, or RRE) designed to help prevent depression in Chinese American teens. It may help by teaching coping strategies before symptoms become more serious.
Boston, MassachusettsAges 14–18 - NCT05949047Recruiting
Phone-based training for family caregivers of Alzheimer’s patients
This study tests a smartphone program that teaches skills to better manage emotions for people who provide unpaid care for someone with Alzheimer’s disease. It may help caregivers feel less overwhelmed and cope more effectively during daily stress.
Houston, TexasAges 18 years+ - NCT05928247Recruiting
Behavior program for frequent challenging behaviors in children
This trial tests a structured (manualized) assessment and treatment approach for children who have very frequent challenging behaviors despite prior help. It aims to reduce these behaviors and improve daily functioning by targeting what keeps the behavior going.
Somerset, New JerseyAges 3–17 - NCT06034821Enrolling by invitationPhase 4
ECT vs. ketamine for suicidal depression in adults
This trial compares two treatments—ECT (electroconvulsive therapy, which uses electrical stimulation) and ketamine (a medicine given as a shot)—to see which works better for quickly reducing suicidal depression. It is for adults who are in a severe depressive episode with active suicidal thoughts.
San Francisco, CaliforniaAges 18–90 - NCT06127004Recruiting
Metacognitive training for negative symptoms
This study tests a training program designed to help people with schizophrenia or related conditions better manage challenging thoughts and feelings. It may be a good fit if you have trouble with motivation, social withdrawal, or low energy (negative symptoms).
Multiple LocationsAges 18 years+ - NCT06085937RecruitingPhase 1
Ketamine for suicidal patients in the ER
This trial tests if a single dose of ketamine can quickly reduce suicidal thoughts in people who come to the emergency department. If you are having active suicidal thoughts and need inpatient care, you may be able to join.
Kansas City, KansasAges 18–65 - NCT05965622Recruiting
Cost-effectiveness of ABFT for youth with suicidality
This study looks at whether ABFT (a family-based therapy) works well and is worth the cost for young adults who have strong suicidal thoughts. It also uses your family’s involvement to see how treatment affects safety and well-being over time.
Tongeren, LimburgAges 18–25 - NCT06018285Recruiting
Reducing suicide risk in teens in primary care
This study tests a step-by-step approach to reduce suicide risk in teens who get primary care. It's designed to help teens and their families get the right support, from talking to a care manager to more intensive help if needed.
Akron, OhioAges 12–17 - NCT06124846Recruiting
Cannabis break and brain changes in teens
This study looks at what happens in the brain when teens with cannabis use disorder stop using cannabis for 6 weeks. It uses MRI scans to see changes in areas that control habits and decisions.
Minneapolis, MinnesotaAges 15–18 - NCT05696704Recruiting
Telehealth program to support mental health in family caregivers
This study tests a video/phone-based program to help reduce anxiety and depression symptoms in people caring for a family member or friend with dementia. It may help caregivers feel better and cope more effectively while caring for someone they love.
Lubbock, TexasAges 18–120 - NCT05748730Recruiting
Care team support program for teens at risk of depression
This study tests an “integrated care” program that supports teens who are dealing with depression symptoms or recent suicidal thoughts. It also involves a parent or caregiver to help improve support at home and connect teens to the right help.
Gibbsboro, New JerseyAges 12–18 - NCT05843604Recruiting
Brain and thinking tests to study OCD treatment resistance
This study looks at brain and thinking (cognitive) markers to understand why some people with obsessive-compulsive disorder (OCD) don’t respond as well to treatment. If you have OCD, you may be asked to take tests and follow the study rules to help researchers better predict treatment resistance.
PoitiersAges 18–70 - NCT05722197Recruiting
Study of coping strategies when feeling suicidal
This study looks at what coping and emotion-regulation strategies you use when you feel suicidal, using frequent short check-ins on your phone. It may help researchers understand which strategies are most helpful during this difficult time.
Columbus, OhioAges 18 years+ - NCT05676827Enrolling by invitation
Study pain and stress in people with long-term jaw muscle pain
This trial looks at how long-lasting jaw (masticatory) muscle pain relates to the nervous system and emotional stress. It may help researchers understand why symptoms persist and guide future treatments.
WroclawAges 18–80 - NCT05902741Recruiting
Race-based stress program for Black women
This trial studies whether a specific stress-reduction program tailored to race can improve stress and health for Black women after menopause. It may help you learn coping skills that could benefit blood pressure, cholesterol, or diabetes-related outcomes.
Maywood, IllinoisAges 50–75
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.