Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT06936202Recruiting
Spirulina pill study for healthy adults
This study tests whether a supplement called spirulina (a type of algae) can improve mental health in healthy adults. You would take spirulina daily and have your mood and well-being checked over several weeks.
Phoenix, ArizonaAges 16–65 - NCT06713616RecruitingPhase 3
Esketamine vs. ketamine for hard-to-treat depression
This study compares the effectiveness of esketamine (Spravato) and another similar drug, ketamine, for adults with major depression that has not improved after trying at least two other antidepressants. It aims to find out which treatment works better.
Milford, ConnecticutAges 18 years+ - NCT06521099Recruiting
A new method to help adults cope with loneliness
This study tests a new approach to reduce loneliness in adults. It may help you if you feel lonely and do not have certain health conditions.
Hong KongAges 18 years+ - NCT06366334Recruiting
Ketamine for Teens with Suicidal Thoughts in the ER
This study tests whether a single dose of ketamine, given through an IV, can quickly reduce suicidal thoughts in teenagers who come to the emergency department. It aims to find a faster way to help teens in crisis.
Ottawa, OntarioAges 12–17 - NCT06720792Recruiting
Escape game for student mental health
This trial tests if playing an escape game can help improve the mental health of university students. If you are a student in France, you may be able to join.
BordeauxAges 18 years+ - NCT07649733Recruiting
Virtual Reality Wellness Program for Healthcare Workers
This study tests whether using virtual reality can help healthcare workers reduce stress and improve well-being. You would attend weekly sessions using a VR headset designed to help you relax.
Badalona, BarcelonaAges 18 years+ - NCT06677359Recruiting
Creatine and exercise for older adults
This study tests whether a creatine supplement, taken with or without a gentle exercise program, can help older adults stay stronger and more independent. It's designed for people aged 75 and older who can still walk.
Pamplona, NavarreAges 75 years+ - NCT06725277Recruiting
Observing ketamine and Spravato for depression
This study follows people who are already taking or about to start IV ketamine or Spravato® for hard-to-treat depression. Researchers want to learn more about how these treatments work in real life.
Milford, ConnecticutAges Any age - NCT07586553Recruiting
Walking Test Study for Older Adults With Memory Concerns
This study tests a special walking pattern called the figure-of-8 walk in older adults who are noticing memory problems but don't have dementia yet. Researchers want to understand how walking ability connects to thinking and memory changes.
Balıkesir, BigadiçAges 65 years+ - NCT06886776Enrolling by invitation
Firearm storage safety program for Illinois families
This trial tests a program that helps parents and caregivers learn about safe firearm storage during their child's checkup at health clinics in Illinois. It aims to prevent injuries by providing secure storage options and education.
Chicago, IllinoisAges Any age - NCT07068971Enrolling by invitation
Sleep well at night for advanced cancer patients
This study tests a sleep program for people with advanced cancer who have trouble sleeping. It aims to help you sleep better at night.
DublinAges 18 years+ - NCT06375083RecruitingPhase 2
Computer therapy for suicide prevention and depression in Veterans
This trial tests two different computer-based therapy programs for Veterans: one for preventing suicide and one for treating depression. Both programs are designed to be done at home on your computer or tablet.
Aurora, ColoradoAges 18–65 - NCT07424781Recruiting
Fluoxetine and emotional experience in young adults
This study looks at whether fluoxetine, a common medication for mood, affects how young adults (18-24) experience emotions. It aims to understand emotional processing in healthy individuals without psychiatric history.
Oxford, OxfordshireAges 18–24 - NCT06728280Recruiting
DTMS for teens with depression: safety and effectiveness
This trial tests if a new type of brain stimulation called DTMS can safely help adolescents with major depression. It may be an option if you have tried other treatments and are looking for a non-medication approach.
Taiyuan, ShanxiAges 11–23 - NCT06671977RecruitingPhase 1
Safety and effects of DMT in healthy adults and those with depression
This trial studies the safety and effects of DMT, a psychedelic compound, in healthy volunteers and people with major depressive disorder (MDD) who haven't responded well to antidepressants. It aims to see how DMT affects the brain and mood.
West Haven, ConnecticutAges 21–65 - NCT07540338RecruitingPhase 1/Phase 2
New Lithium Capsule Study for Bipolar I
This study compares a new lithium capsule (AL001) to a standard lithium capsule in people with Bipolar I Disorder. It aims to see how well your body absorbs each capsule and whether AL001 is safer or more tolerable.
Boston, MassachusettsAges 18–65 - NCT07162493Recruiting
Feasibility trial of ATTACH program for families in Denmark
This trial tests a program called ATTACH to help parents and young children who are facing tough challenges, like mental health problems, substance abuse, or having a child in foster care. If you are a parent with a child under 5.7 years, speak English or Danish, and are getting support from a family treatment center, you may be able to join.
GribskovAges 18 years+ - NCT06379633Recruiting
Virtual reality therapy for teens with social anxiety
This study tests if virtual reality (VR) can help teenagers with social anxiety feel less nervous in social situations. You would use a VR headset to practice facing fears in a safe environment.
LeuvenAges 12–16 - NCT07565428RecruitingPhase 3
Study of roluperidone for negative symptoms of schizophrenia
This trial tests a new medicine called roluperidone for people with schizophrenia who have ongoing negative symptoms (like low motivation or social withdrawal) but stable positive symptoms (like hallucinations). It aims to see if the drug helps with these symptoms and if it can reduce the chance of relapse compared to other medications.
Bellflower, CaliforniaAges 18–55 - NCT07096271Recruiting
Relationship education for military couples
This study tests a relationship education program designed for military couples. It aims to help couples strengthen their bond and improve communication through a retreat.
Bethesda, MarylandAges 18 years+ - NCT05845333Recruiting
Study brain changes in women with recent stimulant use
This trial looks at neurocognitive (thinking and brain function) differences in high-risk women who have used stimulant drugs recently. It may help researchers understand how stimulant use affects the brain and which brain changes are linked to thinking and behavior.
Albuquerque, New MexicoAges 18–70 - NCT07542665Recruiting
Aromatherapy vs Music for Calming Children During Dental X-rays
This study tests whether calming scents (aromatherapy) or soothing music helps children feel less anxious during a routine dental X-ray called panoramic radiography. Researchers want to see which approach works better to make the experience easier for kids.
NiğdeAges Any age - NCT07541716Recruiting
Parenting support to help infants with feeding and sleep difficulties
This study tests a new parenting program designed to help parents of young infants who have feeding, sleeping, or crying challenges. The program uses video lessons and a mobile app to teach parents techniques that may help their baby become calmer and more regulated.
AntwerpAges 18 years+ - NCT07020572Recruiting
Teen mood support program (iMATTER) in primary care
This study tests a group program to help teenagers with mild to moderate depression symptoms feel better. It takes place in primary care and uses a phone, computer, or tablet for activities.
Philadelphia, PennsylvaniaAges 13–17
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.