Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,764 recruiting studies in this area right now.
By phase
- Not applicable6,413
- Phase 2492
- Phase 1247
- Phase 3239
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 367
Top conditions
- Anxiety388
- Depression381
- Alzheimer Disease338
- Autism Spectrum Disorder240
- Dementia226
- Mild Cognitive Impairment195
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder142
- Opioid Use Disorder140
- Stress117
- PTSD105
- Mental Health98
- Autism94
- Mild Cognitive Impairment (MCI)88
- Suicidal Ideation87
Leading sponsors
- VA Office of Research and Development105
- Yale University86
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University61
- University of California, Los Angeles58
- The University of Hong Kong51
- University of Pennsylvania51
- Karolinska Institutet50
Where studies are running
- California517
- Massachusetts266
- New York254
- Texas209
- Maryland175
- Pennsylvania169
- Florida147
- Alabama118
- Arizona109
- Illinois103
Recruiting studies7,764 total
- NCT07651319RecruitingPhase 1/Phase 2
IL-2 and Semaglutide Treatment for Alzheimer's Disease
This study tests whether two drugs—IL-2 (an immune-boosting medication) and semaglutide (a diabetes drug that may help brain function)—can slow memory loss in people with Alzheimer's disease. Researchers believe these drugs together might help reduce brain inflammation and protect memory.
Houston, TexasAges 50–86 - NCT07647380Recruiting
Brain Stimulation to Help Thinking in Schizophrenia
This trial tests a non-invasive brain stimulation technique called transcranial electrical stimulation (TIS) to improve thinking and memory problems in people with schizophrenia. Researchers want to see if this treatment, combined with antipsychotic medications, can help you think more clearly and function better in daily life.
Changsha, HunanAges 18–50 - NCT07650591Recruiting
Tapping and vibration to ease needle pain in children
This study tests whether rhythmic tapping and gentle vibration near the skin can help children ages 6–12 feel less pain and fear during blood draws. Researchers want to see if these simple techniques can make the procedure more comfortable.
Antalya, KepezAges 6–12 - NCT07654179Recruiting
Metformin for depression with obesity: a genetic study
This trial tests if adding metformin to antidepressants helps people who have both depression and obesity. It also looks at genetic factors that might affect treatment response.
Rawalpindi, Punjab ProvinceAges Any age - NCT07646834Recruiting
Brain-Gut Study of IBS with Anxiety and Depression
This study explores how stress and mood changes affect irritable bowel syndrome (IBS) using brain imaging. Researchers will scan your brain and collect health information to understand the connection between your gut and mental health.
Xi'an, ShaanxiAges 18–60 - NCT06687447Recruiting
Helping new moms with milk supply and breastfeeding confidence
This study tests two methods to help first-time mothers who had a C-section feel more confident about their milk supply, reduce anxiety and fatigue, and improve breastfeeding motivation. It compares different ways to support moms after childbirth.
GiresunAges 18 years+ - NCT06686186Recruiting
Hainan Community Memory Study
This study follows older adults in Hainan who live in the community. The goal is to understand thinking and memory changes over time.
Haikou, HainanAges 60–120 - NCT05457140Recruiting
Testing genes and other samples in youth with first psychosis
This study looks at many types of tests (including genetic testing and other lab data) to help understand what may be causing first-time psychosis symptoms in youth. It may help doctors learn more about the condition for future care, and it can involve analyzing family genetic information.
San Diego, CaliforniaAges 7–17 - NCT06197711Recruiting
PRISMA for mental health in pretrial detention
This study tests whether a program called PRISMA can help improve mental health for people in pretrial detention. It is designed for detainees in Zurich and Bern who speak one of nine languages and are not in immediate crisis.
Zurich, Canton of ZurichAges 18 years+ - NCT06419101Recruiting
Finding early signs of memory loss in China
This trial looks for new ways to diagnose memory and thinking problems earlier. It involves a memory test, brain scan, and blood draw to find markers that could help identify cognitive disorders.
BeijingAges 40–90 - NCT06683248Recruiting
Night shifts and menstrual cycle health study
This study looks at how working night shifts affects your health throughout your menstrual cycle. It aims to help understand the risks and support better health for shift workers.
Uppsala, Uppsala CountyAges 18–35 - NCT06689254RecruitingPhase 2
Testing mifepristone for hard-to-treat PTSD in Dutch adults
This study tests a new medicine (mifepristone) to see if it helps people with PTSD that hasn't improved after standard treatments. You must be fluent in Dutch and have tried at least two PTSD treatments, including trauma-focused therapy.
Amsterdam, North HollandAges 18 years+ - NCT07639697Recruiting
Stress Training via Phone for Young Adults
This study tests a phone-based program to help young adults (ages 18–30) manage stress. You'll use a smartphone app and wear a small monitor for 14 days to see if guided training can help you feel better.
Pittsburgh, PennsylvaniaAges 18–30 - NCT07638657Recruiting
Testing a Digital Autism Support App
This study tests Autimia, a digital tool designed to help adults with autism manage stress and emotional difficulties. You'll use the app at home while researchers track whether it improves your wellbeing.
HamburgAges 18–65 - NCT07644052RecruitingPhase 3
Study of a new medicine to ease cannabis withdrawal
This study tests a new medicine, PP-01, to help adults who use cannabis daily and want to quit. It aims to reduce withdrawal symptoms like anxiety, irritability, and sleep problems during the first week after stopping.
Little Rock, ArkansasAges 18–55 - NCT04980794Recruiting
Family conflict resolution program for two-caregiver families
This study tests a family conflict-resolution program to help reduce conflict and improve how families handle disagreements over time. It’s designed for families with two primary caregivers and a child age 4 to 17.
Fort Wayne, IndianaAges 4 years+ - NCT03495440Recruiting
Family skills program for youth with developmental disabilities
This trial studies a parent-and-family intervention designed for families of youth with developmental disabilities. It may help parents and siblings better understand needs and improve day-to-day support at home through guided, theory-based activities and surveys.
Fort Wayne, IndianaAges Any age - NCT05813093Recruiting
Brain stimulation and brain scans for hard-to-treat depression
This trial tests an alternating combination of brain stimulation and brain imaging to see if it helps people with depression that hasn’t improved with usual treatments. The goal is to find a safer, more effective approach for people whose depression has been very difficult to treat.
Toronto, OntarioAges 20–65 - NCT05867940Recruiting
Exercise program for people with disabilities who are not active
This trial studies whether a structured physical activity program can improve health for people with disabilities who currently do not meet recommended activity levels. It focuses on reducing long periods of sitting and encouraging safer movement.
MalmöAges 8 years+ - NCT06032715Recruiting
Reducing sleep medication use in older adults
This trial tests a brief program to help older adults who use sleep medications (Z-drugs) too often or for too long, and see if they can safely reduce or stop them.
LørenskogAges 60 years+ - NCT07639359RecruitingPhase 2
Ketamine for depression in intensive care patients
This study tests whether low-dose ketamine infusions can reduce depressive symptoms in patients staying in the intensive care unit for at least 6 days. Ketamine is a medication that may work differently than standard antidepressants and could provide faster relief.
Jacksonville, FloridaAges 18–99 - NCT07638046RecruitingPhase 2
Mindful Walking and Brain Function in Older Adults
This study looks at how mindful walking—combining walking with focused attention—affects thinking and memory in older adults at risk for dementia. Researchers will track your brain activity and daily movement to see if this approach helps protect brain health.
Columbia, South CarolinaAges 60 years+ - NCT07642661RecruitingPhase 2
Folinic Acid for Autism in Young Children
This study tests whether folinic acid (a B-vitamin supplement) can help improve autism symptoms in children ages 3–6. Folinic acid may support brain function, and researchers want to see if it works better than placebo (a dummy pill).
Jerusalem, N/A = Not ApplicableAges 3–6 - NCT07638553RecruitingPhase 3
Psilocybin to prevent alcohol relapse with depression
This study tests whether psilocybin (a psychedelic compound) can help people with severe alcohol use disorder stay sober longer, especially if they also have depression. Participants receive guided psilocybin sessions alongside counseling to reduce the risk of returning to heavy drinking.
BayonneAges 18 years+
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,764 recruiting psychiatry studies from the U.S. registry right now, out of 12,350 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
- Injuries & trauma
- Mouth & dental
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.