Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 8,192 recruiting studies in this area right now.
By phase
- Not applicable6,797
- Phase 2511
- Phase 1258
- Phase 3244
- Phase 4213
- Phase 1/Phase 298
- Phase 2/Phase 371
Top conditions
- Depression420
- Anxiety412
- Alzheimer Disease342
- Autism Spectrum Disorder258
- Dementia226
- Mild Cognitive Impairment199
- Schizophrenia192
- Major Depressive Disorder188
- Cognitive Impairment157
- Insomnia152
- Alcohol Use Disorder150
- Opioid Use Disorder145
- Stress136
- PTSD110
- Autism95
- Mental Health92
- Suicidal Ideation92
- Anxiety Disorders85
Leading sponsors
- VA Office of Research and Development104
- Yale University95
- Massachusetts General Hospital78
- Stanford University72
- Assistance Publique - Hôpitaux de Paris65
- Johns Hopkins University63
- University of California, Los Angeles61
- The University of Hong Kong52
- University of Pennsylvania52
- Karolinska Institutet50
Where studies are running
- California529
- New York267
- Massachusetts263
- Texas223
- Maryland176
- Pennsylvania175
- Florida153
- Alabama118
- Arizona117
- Connecticut113
Recruiting studies8,191 total
- NCT06385223Recruiting
Personalized brain stimulation for hard-to-treat depression
This study tests a new, personalized form of brain stimulation (called TMS) using MRI scans to target the right areas for people whose depression hasn't improved with medication. It aims to see if this tailored approach works better than standard TMS.
SingaporeAges 21 years+ - NCT07157124Recruiting
Testing visual patterns to reduce alcohol cravings
This study tests whether a simple visual pattern on your computer screen can help reduce alcohol cravings and drinking. If you're a college student who drinks at least once a week and experiences cravings, you may be able to help find a new way to manage urges.
Laramie, WyomingAges 18–29 - NCT07396220Enrolling by invitation
Psychotherapy with esketamine nasal spray for suicidal thoughts
This study tests combining a specific type of therapy (BCBT-SP) with esketamine nasal spray to help people with treatment-resistant depression who are having ongoing suicidal thoughts. The goal is to see if this combination can reduce suicidal ideation more effectively than either treatment alone.
San Diego, CaliforniaAges 18–70 - NCT06735885Recruiting
Brain training with feedback app for depression
This trial tests whether a smartphone app combined with brain scanning (fMRI) can help people with depression. You will get real-time feedback on your brain activity to learn how to improve your mood.
Stanford, CaliforniaAges 18–80 - NCT06387732Recruiting
Exercise for depression: how it works
This trial looks at how physical activity helps improve mood in people with moderate depression. You will be asked to take part in either brisk walking or stretching sessions, so the researchers can measure changes in your depression symptoms and brain function.
LondonAges 18–60 - NCT06736522Recruiting
Youth leadership and mindfulness program for high school students
This study tests a program designed to build leadership skills, engagement, and mindfulness in high school students. If you're a teen in certain Massachusetts or Illinois schools, this program may help you grow personally and socially.
Chicago, IllinoisAges 14 years+ - NCT07085663Recruiting
Exergame brain and body training for adults 50-60 in China
This study tests whether combining exercise video games with memory and thinking tasks can help middle-aged adults who feel their memory is getting worse. It aims to see if this type of training can improve both physical and mental function.
Chengdu, SichuanAges 50–60 - NCT05820581Recruiting
Study of teen emotional regulation and behavior profiles
This study looks at how teens who show behavioral problems understand and manage emotions. It may help researchers better match support to different “mentalization” patterns, which could lead to improved care in the future.
BesançonAges 12–18 - NCT07536568Recruiting
Caffeine to speed recovery after eye surgery in older adults
This study tests whether a small dose of caffeine placed under the tongue helps older adults wake up faster and feel less confused after eye surgery under general anesthesia. Researchers want to see if this simple approach can improve how quickly patients recover and reduce post-surgery agitation.
CairoAges 65 years+ - NCT06740396Recruiting
Depression in heart disease patients in Baghdad
This study looks at how common depression is in people with coronary artery disease and how severe it is. If you have heart disease and are being treated at a hospital in Baghdad, you can help doctors understand the link between heart health and mental health.
BaghdadAges 18 years+ - NCT07082998Recruiting
Heated yoga vs. sauna for depression
This study compares heated yoga with sauna sessions to see which helps reduce depression. You'll also use a mindfulness app. Both treatments are meant to boost mood and well-being.
Boston, MassachusettsAges 18–65 - NCT07021872Recruiting
Reducing loneliness in older adults by boosting positive feelings
This trial tests a program to help older adults feel less lonely by increasing positive emotions. If you are 65 or older, speak Cantonese, and sometimes feel lonely, you may be able to join.
Hong Kong, Hong KongAges 65 years+ - NCT06971549Recruiting
Faster TMS for depression with brain monitoring
This study tests a faster version of TMS (called iTBS) to treat depression, while using a special headband to monitor brain blood flow in real time. It's for people whose depression hasn't gotten better with at least one antidepressant medication.
Hong KongAges 18–65 - NCT07021404Recruiting
Suicide attempts and thoughts in Flanders
This study looks at how many people come to the emergency department in Flanders after a suicide attempt or with suicidal thoughts. It aims to understand the patterns of these events to help improve care and prevention.
AalstAges 12 years+ - NCT07548463Recruiting
Theater Program for Young People with Depression and Anxiety
This study tests whether a playback theater program—where actors improvise scenes based on your stories—can help reduce depression and anxiety in teenagers and young adults. Playback theater is a creative activity that might help you feel heard and connected.
Kowloon Tong, Hong KongAges 13–24 - NCT07536360Enrolling by invitation
Music Therapy for Emotional Health in Nursing Homes
This study tests whether group music therapy sessions can improve emotional well-being and mood in older adults living in long-term care facilities. You would attend group music sessions and answer some questions about how you're feeling.
Taichung, Taichung CityAges 65 years+ - NCT05824728RecruitingPhase 2
Levetiracetam for Parkinson’s psychosis with study partner support
This Phase 2 study tests whether AGB101 (levetiracetam) can reduce hallucinations, delusions, or related symptoms in people with Parkinson’s disease psychosis, while checking safety. You and a study partner will help with dosing and regular check-ins, including MRI scans.
Baltimore, MarylandAges 40–85 - NCT06745765Recruiting
Virtual reality for anxiety during CT-guided biopsy
This study tests whether using a virtual reality (VR) headset during a CT-guided biopsy can help lower anxiety. If you are having this procedure while awake, you may be able to use VR to feel more comfortable.
Bologna, BolognaAges 18 years+ - NCT05638204Recruiting
Suicide crisis support after an attempt or crisis
This trial tests a structured intervention to help people after a suicidal crisis or suicide attempt. It may offer extra support and coping help during a high-risk time, and it also involves a close person when possible.
BeernemAges 18 years+ - NCT07585006RecruitingPhase 1
How nicotine affects the body: comparing e-cigarette liquids
This study compares different nicotine products to understand how they affect your body. Researchers will measure your heart rate, breathing, and blood samples during three short lab visits. The results may help scientists better understand nicotine's effects.
Columbus, OhioAges 21 years+ - NCT07550881RecruitingPhase 2
Intranasal Dexmedetomidine for Sudden Anxiety in Adults
This study tests whether a medication called dexmedetomidine, given as a nasal spray, can quickly relieve sudden anxiety. The goal is to see if this approach works better or faster than current treatments for acute anxiety episodes.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT06746740Recruiting
Trauma-informed exercise for women veterans
This study tests an exercise program designed for women veterans who have experienced sexual violence. The program is virtual and focuses on being safe and supportive.
Boston, MassachusettsAges 21–65 - NCT06630728RecruitingPhase 4
How Addictive Are Very Low Nicotine Little Cigars?
This study is testing whether little cigars with very low nicotine are less addictive than regular ones. Researchers want to see how smoking these affects your mood, cravings, and smoking behavior.
Columbus, OhioAges 21–75 - NCT06747637Recruiting
Spanish-language program for Latino dementia caregivers
This study tests a program designed to support Latino and Hispanic caregivers of people with dementia. It is delivered in Spanish and aims to see if it helps caregivers manage their role and well-being.
Los Angeles, CaliforniaAges 18–100
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 8,192 recruiting psychiatry studies from the U.S. registry right now, out of 13,292 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.