Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07386925Recruiting
Pelargonium oil for baby tooth pulpotomy
This trial tests using Pelargonium graveolens essential oil, a natural plant oil, as a treatment for cavities in baby (primary) molars. It compares the oil to standard treatments to see if it can help preserve the tooth and avoid pain or infection.
Tanta, Cairo GovernorateAges 4–7 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07373184Recruiting
Virtual planning for jaw joint replacement
This study looks back at past jaw joint (TMJ) replacement surgeries to see how virtual planning helped. If you already had this surgery at a specific hospital between 2010 and 2025, you might be included.
LundAges Any age - NCT07377240Recruiting
Understanding barriers to changing eating habits in families with severe tooth decay in young children
This study talks to parents of young children (under 6) with severe early childhood cavities to understand what makes it hard to change risky eating habits. The goal is to help dentists support families better.
Clermont-FerrandAges Any age - NCT07376954Enrolling by invitationPhase 1
Bite correction for children with underbite
This trial tests a special dental device that is glued to the teeth to correct an underbite in children aged 8-11. It aims to improve the way the upper and lower jaws fit together.
Al MansurahAges 8–11 - NCT07374354Recruiting
Pain and anxiety control for kids with MIH
This study tests a pain-relieving medicine given before dental treatment to see if it helps reduce pain and anxiety in children with molar incisor hypomineralization (MIH), a condition that causes weak enamel on molars and front teeth.
GizaAges 6–12 - NCT07377344Recruiting
Gum health care during pregnancy
This trial tests ways to improve gum health during pregnancy. If you have gum disease or are at risk, the study may provide dental care that could help both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT07375940Recruiting
Understanding Behçet Disease in children and teens
This study looks at the health records and blood tests of children and young adults with Behçet disease to learn more about the condition. It also compares their results with healthy children to find clues that may help doctors better understand and treat Behçet disease.
Florence, FlorenceAges 6 months–70 years - NCT07371481Recruiting
Gum graft vs collagen for dental implant gum thickness
This trial compares two ways to thicken the gum tissue around a new dental implant in the lower back jaw. One method uses a small piece of your own gum tissue, the other uses a collagen material.
HanoiAges 18–65 - NCT07377890Recruiting
Digital vs traditional denture impressions: which is more accurate?
This study compares digital scan impressions to traditional putty impressions for making complete dentures. It aims to find out which method is more accurate for people who have no teeth left and need a full set of dentures.
DubaiAges 18–85 - NCT07374341Recruiting
Botox for jaw fractures near the joint
This trial is testing whether guided Botox (botulinum toxin) injections into the chewing muscles can help treat certain types of jaw fractures near the joint. It may be an option if you have a mild to moderate break on one side and your bite is stable.
AlexandriaAges 18–40 - NCT07371468RecruitingPhase 1
Study of an experimental drug for lupus, rheumatoid arthritis, and related conditions
This trial tests a new drug called GSK5926371 for people with certain autoimmune diseases that affect the joints, skin, and other tissues. It aims to see if the drug is safe and how well it works.
Buenos AiresAges 18–70 - NCT06842368Recruiting
Immediate implants with vitamin D or hyaluronic acid bone graft
This study compares two types of bone graft materials mixed with either vitamin D or hyaluronic acid for dental implants placed immediately after a tooth is removed. It aims to see which helps the implant heal better.
CairoAges 18–60 - NCT06843928Recruiting
Titanium brush for treating infected dental implants
This study tests whether using a special titanium brush during a deep cleaning helps treat infected dental implants (peri-implantitis) better than cleaning alone. It's for people who have had gum disease before and have at least one implant with ongoing infection and bone loss.
Barcelona, CataloniaAges 18 years+ - NCT07364565Recruiting
Green tea mouthwash for plaque and gum health
This trial tests whether a pure green tea mouthwash can reduce plaque and gum inflammation better than a placebo or an essential oils mouthwash. It may be a good option if you have healthy gums and are looking for a natural alternative.
Irbid, Irbid GovernorateAges 18 years+ - NCT07362160Recruiting
Comparing two types of palate expanders for kids
This trial compares a newer clear palate expander to the traditional Hyrax expander in children aged 10-14 with a crossbite. The goal is to see which device works better and is more comfortable.
Baghdad, Al-Rusafa, Bab Al-moadhamAges 10–14 - NCT07367737Enrolling by invitation
Comparing histatin-1 levels in smokers and non-smokers with gum disease
This study looks at a protein called histatin-1 in your saliva to see how it changes with gum disease treatment. Researchers want to compare levels between smokers and non-smokers before and after deep cleaning (a non-surgical treatment for periodontitis). It may help understand how smoking affects gum healing.
Baghdad, Medical CityAges Any age - NCT07367464Recruiting
Bone Grafting Methods for Upper Jaw Implants
This trial tests two ways to rebuild the jawbone so there's enough space for a tooth implant. One method uses a mix of man-made bone and donated bone, the other uses man-made bone and your own bone chips. It might help you if you need more bone for an implant in your upper jaw.
CairoAges 20–50 - NCT07368699Recruiting
Gum disease treatment with oxygen gel and light therapy
This trial tests a new gel that releases oxygen combined with a special light treatment to help heal advanced gum disease. It might help if standard treatments haven't been enough.
Alexandria, Bab SharqAges 30–70 - NCT07362979RecruitingPhase 2
Toripalimab with chemo for advanced nasopharyngeal cancer
This trial tests adding toripalimab (an immunotherapy) to two different platinum-based chemotherapy regimens as initial treatment for locally advanced nasopharyngeal carcinoma. The goal is to see if this combination is more effective than standard treatment.
Dongguan, GuangdongAges 18–70 - NCT07368621Recruiting
Gum graft with or without platelet-rich fibrin for dental implant thickness
This trial tests if adding a special blood concentrate (platelet-rich fibrin) to a standard gum graft helps thicken the gum tissue around a dental implant. It is for people with thin gums who are missing a single tooth.
Cairo, Cairo GovernorateAges 18–60 - NCT07364006Recruiting
Accuracy of metal-free guided implant surgery
This study tests a new way to place dental implants in people who need a full set of replacement teeth. It compares the accuracy of a method that uses a metal guide vs. one without it, to see if the simpler method works just as well.
Madrid, MadridAges 18 years+ - NCT07363031Enrolling by invitationPhase 2
Valacyclovir for mouth sores during head and neck radiation
This trial tests whether the antiviral drug valacyclovir can prevent or reduce painful mouth sores caused by radiation therapy for head and neck cancer.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06074952Recruiting
Color stability of denture teeth in staining solutions
This trial tests how well different acrylic denture teeth keep their color when soaked in various staining liquids. It uses only specific front teeth (maxillary central incisors) that are flat on the surface and made of a special acrylic called IPN.
Karachi, SindhAges Any age
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.