Clinical trials
Atrial Fibrillation, Paroxysmal or Persistent clinical trials
Below are recruiting atrial fibrillation, paroxysmal or persistent clinical trials, each written for real people, not researchers. We’re tracking 472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05565781Recruiting
Watch for hidden atrial fibrillation after unexplained stroke
This study uses a smartwatch and a longer heart-monitoring test (a Holter) to find an irregular heart rhythm called atrial fibrillation after a stroke whose cause is unclear. If they detect it, it may help guide better prevention and treatment to reduce future stroke risk.
Barcelona, CataloniaAges 55 years+ - NCT05794386Recruiting
Ablation plan guided by left-heart scar map for persistent atrial fibrillation
This study tests whether using a 3D heart “scar map” helps doctors choose a better catheter ablation strategy for people with persistent atrial fibrillation (AF). It may help reduce ongoing AF by targeting the scar area in the left atrium.
Seoul, Jongno-guAges 19 years+ - NCT05903170Recruiting
Shock energy study for heart rhythm conversion in atrial fibrillation
This trial tests whether using a specific “shock energy” during electrical cardioversion works safely and effectively for people with persistent atrial fibrillation. You might be eligible if your cardioversion is planned (not an emergency) and your doctors determine you can safely take blood thinners.
Wellington, Wellington RegionAges 18 years+ - NCT05908955Recruiting
Atrial fibrillation ablation with extra vein targeting
This trial studies a modified ablation procedure that targets the superior vena cava in addition to the pulmonary veins to help stop episodes of paroxysmal (coming and going) atrial fibrillation. It may help people whose symptoms continue despite antiarrhythmic medicines.
Beijing, Beijing MunicipalityAges 40–75 - NCT06023888Recruiting
Heart rhythm analysis for persistent atrial fibrillation
This study tests a new way to analyze heart signals in people with long-standing atrial fibrillation that hasn't gotten better with medication. It may help doctors understand your heart rhythm better and guide future treatments.
TaipeiAges 20–80 - NCT06363604Recruiting
Alcohol injection with ablation for persistent atrial fibrillation
This trial is testing a new approach to treat persistent atrial fibrillation (a type of irregular heartbeat) by combining standard catheter ablation with a special injection of alcohol (ethanol) into certain heart veins. It may help people whose symptoms haven't improved with medication.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06455098Recruiting
Pulsed field ablation for paroxysmal atrial fibrillation
This study tests a new procedure called pulsed field ablation using a special catheter to treat paroxysmal atrial fibrillation (AF), a type of heart rhythm problem that comes and goes. It may be an option for people whose AF hasn't been controlled well with medication.
Phoenix, ArizonaAges 18–80 - NCT06654401Recruiting
Using electrical shock to restore normal heart rhythm after surgery
This study looks at whether giving an electrical shock (cardioversion) right after heart surgery can help people with long-lasting atrial fibrillation keep a normal heartbeat. It may help guide future treatment decisions for patients who have not gotten better with medication.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06696170Recruiting
New catheter for atrial fibrillation using nanosecond pulses
This trial tests a new catheter that uses very short electrical pulses to treat atrial fibrillation (a type of irregular heartbeat). It may help people whose AF symptoms continue despite medication.
HasseltAges 18–75 - NCT06825104Recruiting
Long-term comparison of two ablation methods for persistent AF
This long-term study follows people who already completed a 12-month study comparing two types of heart ablation for persistent atrial fibrillation. It looks at how well the treatments worked over time.
BronAges 18 years+ - NCT06833138Recruiting
Pacing vs medication for heart rate control in AF with heart failure
This trial tests whether a procedure that regulates your heart rhythm (pacing) works better than medication for people who have permanent atrial fibrillation, heart failure with a normal pumping strength, and were hospitalized for heart failure in the past year.
AalstAges 18 years+ - NCT06960252Recruiting
Cycle length mapping for long-term atrial fibrillation
This study tests a new mapping technique to find chaotic electrical signals in the heart during persistent atrial fibrillation. It may help doctors better target treatment for people whose atrial fibrillation does not stop with medication.
Taipei, Outside USAges 20 years+ - NCT07095959Recruiting
Ethanol vein infusion plus pulsed field ablation for paroxysmal AF
This study compares two treatments for paroxysmal atrial fibrillation (AF that comes and goes): using pulsed electric field ablation alone versus combining it with ethanol infusion into a specific vein. The goal is to see which approach works better for first-time ablation patients.
Beijing, Beijing MunicipalityAges 18 years+ - NCT02558699Recruiting
Virtual mapping guided catheter ablation for atrial fibrillation
This trial tests whether a “virtual” computer map created from your heart scans can help doctors do catheter ablation to treat atrial fibrillation (AF). It aims to improve the procedure for people whose AF symptoms were not controlled well with anti-arrhythmia medicines.
SeoulAges 19–80 - NCT02932007RecruitingPhase 2
Chloroquine to treat ongoing atrial fibrillation symptoms
This trial tests whether chloroquine can reduce symptoms in people with persistent atrial fibrillation (AF), an irregular heartbeat that lasts longer than a week. It will also closely monitor heart rhythm and safety, since the medicine can affect the heart and other organs.
Tampa, FloridaAges 18 years+ - NCT07508618RecruitingPhase 4
Qidong Yixin Granule for preventing atrial fibrillation after ablation
This trial tests whether a traditional Chinese medicine granule, Qidong Yixin, can help prevent atrial fibrillation from coming back after a heart ablation procedure. It is for people with persistent atrial fibrillation who have not had good results from other heart rhythm medications.
HangzhouAges 18–80 - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT07096219Enrolling by invitation
Catheter Ablation for Leaky Mitral Valve in Persistent Atrial Fibrillation
This trial tests if catheter ablation—a procedure to fix heart rhythm—can help people with a leaky mitral valve that is caused by atrial fibrillation (functional mitral regurgitation). If you have persistent atrial fibrillation and moderate leaky valve, you may benefit from this treatment.
Guangzhou, GuangdongAges 18–75 - NCT07308847Recruiting
Study of a new catheter system for treating atrial fibrillation
This trial tests a new catheter and mapping system designed to treat paroxysmal atrial fibrillation (AF), which is a type of irregular heartbeat that comes and goes. If you have this condition, the study aims to see how well the new system works with a minimally invasive procedure.
Jonesboro, ArkansasAges 18–80 - NCT06929897Enrolling by invitation
Comparing Two Ablation Methods for Persistent Atrial Fibrillation
This study compares two types of ablation (a procedure that uses energy to fix irregular heartbeats) for people with persistent atrial fibrillation. It tests whether adding extra treatment to the back of the heart's left upper chamber helps improve outcomes compared to standard treatment alone.
SeoulAges 20–80 - NCT05292209RecruitingPhase 2
RiLuzole pill to reduce atrial fibrillation on heart monitoring
This Phase 2 study tests whether riLuzole can reduce episodes of atrial fibrillation (an irregular heart rhythm) around the time of planned cardioversion. Doctors will monitor your heart using a Holter monitor to count and compare rhythm episodes.
Salt Lake City, UtahAges 18 years+ - NCT05826665Recruiting
Study of heart rhythm mapping during AF ablation
This is an observational study that looks at how a special heart mapping system may affect the procedure and outcomes for people having ablation for persistent atrial fibrillation (AF). It may help doctors better understand what works best and how procedures turn out.
Jonesboro, ArkansasAges 18–80 - NCT06096246Recruiting
Comparing treatments for persistent atrial fibrillation
This study compares two treatments for persistent atrial fibrillation (AF) that lasts more than 7 days but less than 2 years: electrical cardioversion (a shock to reset your heart rhythm) versus catheter ablation (using radio waves to fix the heart's electrical pathways). It aims to find which option works better for patients like you.
LondonAges 18–85 - NCT06383975Recruiting
Two new treatments for AF that returned after first procedure
This trial tests two new treatments for persistent atrial fibrillation that came back after an initial procedure. One uses a targeted chemical injection, the other uses a special energy field to re-isolate the veins involved.
BrugesAges 18 years+
Hear when a new Atrial Fibrillation, Paroxysmal or Persistent trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for atrial fibrillation, paroxysmal or persistent?
- Yes. Clin2 currently lists 472 recruiting atrial fibrillation, paroxysmal or persistent studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a atrial fibrillation, paroxysmal or persistent trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a atrial fibrillation, paroxysmal or persistent trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.