Clinical trials
Respiratory Mechanics clinical trials
Below are recruiting respiratory mechanics clinical trials, each written for real people, not researchers. We’re tracking 111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06514209Recruiting
Muscle relaxation levels in severe ARDS patients
This study is testing whether different levels of muscle relaxation (called neuromuscular blockade) during breathing support can improve lung function in people with serious ARDS. It might help doctors choose the best relaxation level for patients on a breathing machine.
Nanjing, JiangsuAges 3 weeks–85 years - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT07761468Enrolling by invitation
Standardized medication dosing for ICU patients on ventilators
This study is testing a standardized way to adjust a medication used to help people on ventilators in the ICU. It aims to see if a more consistent dosing approach can help patients breathe better and possibly come off the ventilator sooner.
Querétaro City, QuerétaroAges 18 years+ - NCT06474559RecruitingTeam says not enrolling
Comparing two breathing tubes during urology surgery
This trial compares a special breathing tube (LMA Protector) with a standard tube (ETT) to see which one works better for patients having planned urological surgery. It checks how easy it is to breathe with the machine and the risk of stomach contents getting into the lungs.
PátraiAges 18 years+ - NCT06014138RecruitingPhase 2/Phase 3
Volatile sedation study for ARDS patients
This trial is comparing a new type of inhaled sedative (volatile sedation) to usual IV sedatives for people with ARDS who are on a ventilator in the ICU. It aims to see if it can help patients breathe better and recover more quickly.
London, LondonAges 17 years+ - NCT07175194Recruiting
Matching lung scans to ventilator settings in acute breathing failure
This study uses two lung imaging tests—CT scan and EIT (a non-invasive electrical test)—to find the best ventilator pressure for people with sudden breathing failure. The goal is to tailor settings to your lungs and potentially improve breathing support.
Milan, MilanAges 18 years+ - NCT07325812Recruiting
Lung opening maneuvers during spine surgery
This study tests whether periodic lung opening maneuvers during back surgery can reduce lung collapse and improve breathing mechanics. Doctors will use ultrasound to monitor your lungs.
IstanbulAges 18–65 - NCT06994442RecruitingPhase 3
Best pain relief for children on a breathing tube
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
Little Rock, ArkansasAges 2 months–17 years - NCT04524585Recruiting
Tested a muscle-relaxing treatment for severe low-oxygen breathing
This study tests whether partially relaxing the breathing-related muscles can help people with severe low oxygen while they are on a breathing machine. It may improve how well the lungs work by changing the way the muscles affect breathing.
Toronto, OntarioAges 18 years+ - NCT07001696Recruiting
Predicting breathing support needs with chest X-ray and blood gas
This trial looks at whether combining a chest X-ray and a blood gas test can help doctors decide if a critically ill patient needs a breathing machine (mechanical ventilation). It aims to find a better way to make this important decision.
Zagazig, Al SharqiaAges 18 years+ - NCT03963622Recruiting
Test of careful breathing support for severe lung distress
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
New York, New YorkAges 18 years+ - NCT06203405Recruiting
Sedation guided by breathing effort in ICU patients
This trial tests a new way to manage sedation (medication to keep you calm and comfortable) for people on a breathing machine. The goal is to see if adjusting sedation based on your breathing effort leads to better outcomes and shorter time on the machine.
Bangkok, BangkokAges 18 years+ - NCT05689476Recruiting
Measuring diaphragm breathing signals during ICU ventilation
This study measures electrical activity of the diaphragm and how your breathing system works while you are on a breathing machine in the ICU. It may help doctors better understand breathing during recovery after major lung events.
Padova, ItalyAges 18 years+ - NCT06961227Recruiting
Comparing two breathing machine settings in the ICU
This trial compares two different ways a breathing machine can help you breathe. It uses a special imaging technique to see which method works better for patients in the intensive care unit.
SanliurfaAges 18 years+ - NCT06483529Recruiting
Measuring lung function in ventilated patients
This trial is testing a new way to measure how your lungs are working while you are on a ventilator. It uses a gentle, low-frequency wave to check your lung function without any extra stress.
Jette, Brussel Hoofstedelijk GewestAges 18 years+ - NCT07550738Recruiting
Breathing machine settings during laparoscopic cancer surgery
This study compares two different ways of controlling breathing machines during laparoscopic (minimally invasive) abdominal cancer surgery. Researchers want to see which method keeps your heart and blood flow stable and protects your lungs during surgery.
AsyutAges 20–80 - NCT07392086Recruiting
Comparing two types of ventilation during one-lung surgery
This trial compares two ways of helping you breathe during chest surgery: flow-controlled ventilation and volume-controlled ventilation. The goal is to see which method works better for oxygen and lung protection while one lung is temporarily deflated.
Ankara, YenimahalleAges 18–80 - NCT06448988Enrolling by invitation
Lung function in two surgical positions
This study measures how well your lungs work while you are lying on your back versus in the side-lying park-bench position during brain or spine surgery. It aims to help doctors understand which position is easier for you to breathe in.
RomeAges 18 years+ - NCT04912960Recruiting
PEEP breathing support for adults with acute lung failure
This trial studies whether a specific breathing setting called PEEP can help adults whose lungs are failing and who need a breathing machine. Doctors will compare outcomes in patients who fit this critical illness pattern and are safe for the required positioning and ventilator settings.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT06936618Recruiting
Electrical impedance guided ventilator settings for breathing failure
This trial tests whether using electrical impedance tomography (EIT), a safe and non-invasive monitoring technique, helps doctors set the ventilator better for patients with low oxygen levels. It may improve your breathing support during mechanical ventilation.
BangkokAges 18 years+ - NCT06501118Recruiting
Oxygen levels in ICU patients on breathing machines
This study tests whether giving a little more oxygen to ICU patients on breathing machines leads to better recovery. It compares usual oxygen levels to a more liberal target to see which is safer and more effective.
Aurora, ColoradoAges 18 years+ - NCT06464224Recruiting
Breathing effort patterns in patients coming off the ventilator
This study observes how your breathing effort changes as doctors try to remove you from the breathing machine (ventilator). It helps understand why some patients have trouble breathing on their own after being on the ventilator.
Rio de JaneiroAges 18 years+ - NCT06042621Enrolling by invitation
Improving communication in the ICU for patients, families, and staff
This study looks at how doctors, nurses, and other healthcare team members talk with patients and their families in the intensive care unit (ICU). It aims to improve understanding and support for everyone involved.
Chicago, IllinoisAges 18 years+ - NCT05207046Recruiting
Study for people on a breathing machine after spine trauma
This trial studies how care is given to people who have a traumatic injury to the spine and need a breathing machine. It may help improve treatment and recovery for people who are ventilated after injury, including those with or without spinal cord damage.
Toronto, OntarioAges 16 years+
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Common questions
- Are there clinical trials for respiratory mechanics?
- Yes. Clin2 currently lists 111 recruiting respiratory mechanics studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a respiratory mechanics trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a respiratory mechanics trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.