Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT07185802Recruiting
PRP injection for recent ACL injury
This trial tests whether a shot of your own concentrated platelets (PRP) into the knee improves healing after a recent ACL injury. It's for people with mild to moderate ACL tears and no major other knee damage.
DhakaAges 18–50 - NCT07184554Recruiting
Nerve block for chronic back pain from disc herniation
This study tests whether a nerve block (called an erector spinae plane block) can help relieve chronic low back and leg pain caused by a herniated disc at L4-L5 or L5-S1, when other treatments have not worked.
AnkaraAges 18–75 - NCT07190339Recruiting
Nerve block for hip osteoarthritis pain
This trial tests whether blocking specific nerves in the hip and groin area can reduce pain from hip osteoarthritis when standard treatments like painkillers or physical therapy haven't worked.
AnkaraAges 18–75 - NCT07191743Recruiting
Functional Assessment in ICU Patients
This study observes how well adults in the intensive care unit (ICU) can function in daily activities, like moving and caring for themselves. It aims to understand recovery and may help improve care for future ICU patients.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07189819Recruiting
Closed-loop FES system for improving walking after stroke
This study tests a new electrical stimulation system that adapts in real time to help people who have had a stroke walk better. It may improve your step and make walking feel more natural.
Atlanta, GeorgiaAges 40–90 - NCT07188285Enrolling by invitation
Immune system study for active autoimmune diseases
This study uses a blood test called mass spectrometry to look at the immune system in people with active autoimmune diseases. It aims to find patterns that could help doctors better understand and treat these conditions.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06946940RecruitingPhase 2
Cannabis oil for fibromyalgia pain
This trial tests whether cannabis oil can help people with fibromyalgia who still have pain despite trying other treatments. Participants will receive cannabis oil, and researchers will look for biological markers that predict who responds best.
HaifaAges 30 years+ - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT06947213Recruiting
Orthorexia nervosa in women with postmenopausal osteoporosis
This study looks at whether women with osteoporosis after menopause have a higher risk of orthorexia nervosa, an unhealthy obsession with healthy eating. It aims to compare women with and without osteoporosis to understand the connection.
IstanbulAges 55–75 - NCT06947655Recruiting
Tourniquet types for knee replacement surgery
This study compares different types of tourniquets (tight cuffs) used during knee replacement surgery to see how they affect blood loss and how satisfied surgeons are with them.
Bonn, North Rhine-WestphaliaAges 18 years+ - NCT07183579Recruiting
Finding the right dose of burosumab for XLH
This study looks at how young people with X-linked hypophosphataemia (XLH) respond to different doses of burosumab. The goal is to find the best dose to manage the condition.
NottinghamAges 2–18 - NCT07177378Enrolling by invitation
Double flap closure for jaw bone damage from medication
This trial tests a surgical technique using a double tissue flap to close the jawbone in patients with medication-related osteonecrosis of the jaw (MRONJ). The goal is to improve healing and reduce complications.
TantaAges Any age - NCT07178223Recruiting
Thumb base replacement surgery for arthritis
This study tests a new type of thumb joint replacement surgery for people with arthritis at the base of the thumb. The goal is to see if it relieves pain and improves function better than current treatments.
StockholmAges Any age - NCT07180979RecruitingPhase 4
Nerve blocks for pain relief after hip replacement
This trial compares three types of nerve blocks to find which provides the best pain relief after a hip replacement. It may help you have less pain and a smoother recovery.
PoznanAges 65–100 - NCT07180940RecruitingPhase 4
Comparing two medicines added to a nerve block for back surgery
This study compares two medicines (dexamethasone and dexmedetomidine) added to a nerve block for pain control during and after lower back surgery. It aims to see which one works better for reducing pain and the need for other painkillers.
PoznanAges 18 years+ - NCT07178288Recruiting
Pain sensitivity test for tennis elbow patients
This study measures how sensitive your elbow is to pressure and how your body controls pain, comparing people with and without tennis elbow. It aims to understand pain processing in tennis elbow.
Zarqa, Zarqa GovernorateAges Up to 60 years - NCT07180537Recruiting
Health course for joint and mood conditions
This study tests an online health course that helps improve diet and self-care to support cell health and wellbeing. It is for people with certain rheumatological conditions like rheumatoid arthritis, lupus, or psoriatic arthritis, who also have mood concerns.
Iowa City, IowaAges 18–100 - NCT07178353Recruiting
How bedrest affects leg muscles in young adults
This study looks at how 5 days of complete bedrest changes the leg muscles of healthy young adults. It may help researchers understand muscle loss and how to prevent it.
Kingston, OntarioAges 18–30 - NCT07183774Recruiting
Does muscle loss affect shoulder tear patterns?
This study looks at whether sarcopenia (age-related muscle loss) affects the type of rotator cuff tear you have. You'll get a shoulder MRI to check your rotator cuff and muscle measurements.
Istanbul, ÜsküdarAges 40–75 - NCT07177521Recruiting
Short dental implants after tooth extraction
This study tests whether short implants placed right after a tooth is pulled are stable and work well. It may be a good option if you need a single back tooth replaced and are generally healthy.
BariAges 18–75 - NCT07183215Enrolling by invitationPhase 2/Phase 3
Turmeric capsules for knee osteoarthritis inflammation
This study tests whether a turmeric capsule (curcumin) can reduce inflammation in people with knee osteoarthritis. It may help with pain and swelling without the side effects of standard anti-inflammatory drugs.
YogyakartaAges 60 years+ - NCT07178028Enrolling by invitation
Balance check: in-person vs. video for older adults
This study compares in-person balance assessments with video-based (telehealth) assessments for older adults. It aims to see if balance can be checked reliably over a video call, making it easier for you to participate from home.
Istanbul, BüyükçekmeceAges 65 years+ - NCT07179016Recruiting
Acupressure for chronic pain in rural areas
This trial tests if a self-managed acupressure program can help people living in rural areas manage long-term muscle or joint pain, like neck, back, or knee pain. You would learn to press small seeds on your ear to ease pain.
Columbia, South CarolinaAges 18–85
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.