Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,610 recruiting studies in this area right now.
By phase
- Not applicable3,773
- Phase 2214
- Phase 4199
- Phase 1182
- Phase 3138
- Phase 1/Phase 270
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis173
- Rheumatoid Arthritis131
- Fibromyalgia104
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee65
- Shoulder Pain48
- Hip Osteoarthritis43
- Degenerative Disc Disease39
- Psoriatic Arthritis39
- Chronic Pain38
- Total Knee Arthroplasty38
- Systemic Lupus Erythematosus37
- Duchenne Muscular Dystrophy36
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital24
- Hacettepe University23
- Tanta University22
Where studies are running
- California206
- New York86
- Florida83
- Maryland76
- Arizona71
- Massachusetts71
- Texas66
- Alabama60
- Illinois50
- Pennsylvania47
Recruiting studies4,610 total
- NCT06934278RecruitingPhase 3
Plasma vs salt water for scoliosis surgery in kids
This study compares two types of fluids—one made from donated human blood plasma and one a standard salt-solution—given during scoliosis surgery in children and teenagers. The goal is to see which fluid helps patients recover safely and with fewer complications.
HelsinkiAges 10–21 - NCT06140927RecruitingPhase 3
Ketamine's effect on spinal monitoring during back surgery
This study tests if giving ketamine during certain back surgeries affects how well doctors can monitor your spinal nerves during the operation. It's for adults having a posterior spinal fusion.
San Francisco, CaliforniaAges 18–100 - NCT06666829Recruiting
Personalized rehab with robotics for kids with developmental disabilities
This trial tests a personalized rehabilitation plan that uses new technology and robotic devices to help children and teens with developmental disabilities. The goal is to see if combining these tools can improve daily skills and quality of life.
Genova, GenovaAges 5–21 - NCT07141004RecruitingPhase 4
Study of guselkumab for psoriatic arthritis in Indian patients
This trial tests if guselkumab, a drug given as an injection under the skin, can help people with psoriatic arthritis (PsA) who haven't had enough relief from standard treatments. It aims to find a new option for managing joint pain and swelling.
AhmedabadAges 18 years+ - NCT07138066Recruiting
Smart crutch tips for guided weight-bearing after tibia fracture
This trial tests a smart crutch tip that helps guide how much weight you put on your leg while recovering from a broken shin bone. It is for people who have had surgery to fix the fracture and are learning to walk again with crutches.
Kyiv, Kyiv OblastAges 18–80 - NCT07135817Recruiting
Pre-surgery radiation for spinal tumors
This trial tests whether giving focused radiation before surgery can improve treatment for spinal tumors that have spread from other cancers. It may help people who need surgery for a spinal tumor and have a life expectancy of more than 6 months.
GöttingenAges 18 years+ - NCT07135843Recruiting
Digital home exercise program after hip replacement
This study tests a home-based digital program that encourages physical activity in older adults after hip replacement surgery. It aims to help you stay active and recover better from home.
Heidelberg, Baden-WurttembergAges 65 years+ - NCT07138807Recruiting
Neck exercises for female nurses with neck pain
This study compares two types of neck exercises to see which works better for reducing neck pain and disability in female nurses. You may be able to join if you are a nurse with moderate neck pain and a tender spot in your upper back muscle, and haven't had treatment for it in the past month.
Faisalabad, Punjab ProvinceAges 18–30 - NCT07138729Recruiting
Imaging test for rheumatoid arthritis inflammation
This trial tests a new imaging scan (SPECT) that uses a special tracer (99mTc-TCR-FAPI) to see inflammation in the joints of people with rheumatoid arthritis. It aims to help doctors better understand and track disease activity.
Beijing, Beijing MunicipalityAges 18–75 - NCT07141888Recruiting
Probiotic supplement for high uric acid
This study tests whether a probiotic food supplement can lower high uric acid levels, which often cause gout. It might help you if your uric acid is high but you haven't had a recent gout attack.
ÖrebroAges 18–80 - NCT07140367Recruiting
Artery treatment for inflammatory knee arthritis
This trial tests if a minimally invasive procedure that blocks small arteries can reduce pain and swelling in arthritic knees. It's for people with moderate knee osteoarthritis who still have pain after trying other treatments and are already considering knee replacement surgery.
Bologna, BolognaAges 40 years+ - NCT07141017Recruiting
Global evaluation study for recent axial spondyloarthritis
This study is for people recently diagnosed with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine). It tests whether a standardized global review and education program can help patients better understand and manage their condition.
BesançonAges 18–80 - NCT07139938Recruiting
Spinal decompression without implants for lumbar stenosis
This trial tests whether removing pressure on spinal nerves alone, without any hardware, can help fix spine balance and reduce pain in people with lumbar stenosis. It is for those who have had leg pain or trouble walking for at least 3 months and plan to have surgery without implants.
MoscowAges 18 years+ - NCT07141069Recruiting
Art therapy for adults with chronic low back pain
This study tests whether making art (art therapy) can help adults with ongoing low back pain feel better. You would take part in art sessions to see if this approach reduces pain and improves your quality of life.
Hong Kong, Hong KongAges 18–59 - NCT07141043Recruiting
Bone health study after kidney transplant
This study looks at bone and mineral disorders in people on dialysis, after a kidney transplant, or with bone thinning. It aims to understand how these conditions affect bone health.
IașiAges 20–70 - NCT07137754Recruiting
Physiotherapy for minor injuries in the emergency department
This study tests whether a physiotherapy-led care model in the emergency department can help people with minor muscle or bone injuries recover better and at a lower cost. If you join, you'll see a physiotherapist instead of a doctor for your arm or leg injury.
Aarhus NAges 18 years+ - NCT07142174Recruiting
New implant for neck pain and nerve compression
This trial tests a new type of implant that is placed in the back of your neck to help open up space for nerves and improve spine alignment. It may help people with pain, numbness, or weakness from a pinched nerve or spinal cord compression caused by wear-and-tear changes.
RiyadhAges 18 years+ - NCT07138898RecruitingPhase 2
Managing immune medications for shoulder replacement in rheumatology patients
This trial tests two ways of managing your immunosuppressant medication around the time of shoulder replacement surgery. The goal is to see if one approach leads to fewer infections while still controlling your rheumatic disease.
New York, New YorkAges 18 years+ - NCT07136844Recruiting
Walking and arm movement study for nerve and muscle conditions
This study uses motion analysis to understand walking and arm function in adults with certain neurological or metabolic diseases. The goal is to find patterns that help doctors better manage these conditions.
LiègeAges 18 years+ - NCT07141082Recruiting
Art therapy for older adults with long-term back pain
This study tests whether expressive art therapy (like drawing, painting, or music) can help older adults manage chronic low back pain. It aims to reduce pain and improve quality of life without medication.
Hong KongAges 60 years+ - NCT07135765Recruiting
MRI muscle study for scoliosis in children
This study uses high-resolution MRI to look at back muscles in children with scoliosis (a curved spine). It may help doctors understand muscle differences between types of scoliosis.
GarchesAges 10–17 - NCT07138963Recruiting
Gene study in children with congenital muscle weakness
This study looks at how genes affect symptoms in children with congenital myopathies or congenital muscular dystrophies. It may help doctors better understand these conditions.
CairoAges 1–18 - NCT05555394Recruiting
Body Awareness Therapy for Fibromyalgia Symptoms
This trial studies whether a therapy focused on body awareness can improve symptoms in people with fibromyalgia. It also checks certain biological markers to better understand how fibromyalgia may change over time.
Igualada, BarcelonaAges 18–65 - NCT05721859Recruiting
Study of a hip implant viewing feature during revision surgery
This study checks how well a specific hip implant component (the M‑Vizion femoral component) can be used during revision total hip replacement. It aims to see whether the implant’s intended design works reliably for patients who need hip revision surgery.
Chicago, IllinoisAges 21–80
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,610 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,529 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.