Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT03192267Recruiting
Study of lung changes in early rheumatoid arthritis
This study looks at lung health in people with early rheumatoid arthritis (RA). It may help doctors understand how RA affects the lungs soon after diagnosis and guide better care.
Omaha, NebraskaAges 19–90 - NCT06486506Recruiting
Results of thigh bone replacement after bone tumor surgery
This study looks back at patients who had surgery to replace the top part of the thigh bone after a bone sarcoma. Researchers want to understand how well these surgeries worked over time.
Bologna, BOAges 18–90 - NCT06486753Recruiting
A study testing a new stitch for bunion surgery
This trial is testing a new way to close the incision during a specific type of bunion surgery (called a Chevron osteotomy). The goal is to see if this stitch helps with healing and reduces scarring.
Houston, TexasAges 18 years+ - NCT06487130Recruiting
Australia menopause registry study
This study is building a registry to better understand and support Australians going through perimenopause or menopause. By joining, you help researchers learn about the experiences and needs of people in this stage of life.
AdelaideAges 18 years+ - NCT06487624RecruitingPhase 1
Study of HCB301 for advanced solid tumors and Hodgkin lymphoma
This trial tests a new drug called HCB301, which targets proteins that help cancer hide from the immune system. It is for people with advanced solid tumors or classical Hodgkin lymphoma who have tried other treatments without success.
Greenville, South CarolinaAges 18 years+ - NCT06487741Recruiting
Stretching at home for fibromyalgia pain relief
This study tests whether a simple home stretching program can help relieve fibromyalgia symptoms. You would be asked to do stretches at home and report how you feel.
AalborgAges 18–60 - NCT06488144RecruitingPhase 3
Knee arthritis rehab: helping veterans keep improving
This study tests a program that helps veterans with knee osteoarthritis keep up the gains they make in physical therapy. It uses a Fitbit and a smartphone app to support you and track your activity after your PT sessions end.
Birmingham, AlabamaAges 40–90 - NCT06488547Recruiting
Stress and muscle health study for Greek workers
This trial looks at how stress affects muscle and bone health in employees. If you join, you'll answer questions and be measured with simple electronic devices. The goal is to find ways to help workers stay healthy.
Larissa, Biopolis- LarissaAges 19 years+ - NCT06488872Recruiting
Using CT scans to check bone and muscle health in older adults
This study checks if CT scans can measure bone and muscle health as well as standard tests in older adults. If you've had a recent CT scan and simple strength or walking tests, your data may help improve care for seniors.
Basel, Canton of Basel-CityAges Any age - NCT06489873Recruiting
Lutein, Zeaxanthin, and Fish Oil for Macular Health
This study tests whether taking daily supplements of lutein, zeaxanthin, and fish oil can improve the protective pigment in your eyes. It may help people with low macular pigment and good vision who are not already taking high doses of these nutrients.
College Station, TexasAges 18–45 - NCT06489977Recruiting
Rigid corset for spine infection: a care practice study
This study looks at how rigid corsets are used to immobilize the spine in patients with a spinal infection called spondylodiscitis. It aims to understand current practices and may help improve care.
Clermont-FerrandAges 18 years+ - NCT06490692Recruiting
Blood flow restriction training for tennis elbow
This trial tests if adding blood flow restriction training to physical therapy can improve grip strength and wrist movement for people with recent tennis elbow. It aims to find a better way to recover from this condition.
BeirutAges 18–28 - NCT06490887Recruiting
Spine unit modeling with high-throughput analysis (SUIT)
This study looks at cells from people with degenerated discs or from donated fat or placenta tissue. It aims to understand how these cells work and might help develop new treatments for back pain.
Milan, MIAges 18–60 - NCT06491212Recruiting
Flat feet linked to breathing and balance study
This study looks at whether people with flat feet have differences in their diaphragm (a breathing muscle), balance, and foot pressure compared to people with normal arches. It may help understand how flat feet affect overall movement and stability.
Antalya, AlanyaAges 18–30 - NCT06491745Recruiting
Shock wave therapy for frozen shoulder
This study tests whether adding shock wave therapy to standard treatments (physical therapy and a corticosteroid injection) helps people with frozen shoulder recover faster. If you have significant shoulder stiffness and pain, you might benefit from this extra treatment.
TaipeiAges 20–80 - NCT06492148Recruiting
Myofascial Release for Period Pain in Women
This study tests a gentle hands-on technique called myofascial release to see if it can reduce period pain in women who have primary dysmenorrhea (painful periods without an underlying condition). If you have moderate to severe cramps and don't use hormonal birth control, you may be able to join.
AnkaraAges 18–35 - NCT06492200Recruiting
High-Fiber Diet for Rheumatoid Arthritis
This study tests whether eating more high-fiber foods can improve rheumatoid arthritis symptoms by changing the bacteria in your gut. You would follow a special diet and have your disease activity monitored.
WürzburgAges 18–99 - NCT06494618Recruiting
Botulinum toxin plus shockwave for leg spasticity in cerebral palsy
This study tests if combining botulinum toxin injections with radial extracorporeal shockwave therapy (RESWT) works better than injection alone for reducing leg spasticity in children with cerebral palsy. If your child has spasticity in leg muscles and is already receiving botulinum toxin, they may benefit from this additional therapy.
Istanbul, KadikoyAges 2–18 - NCT06494709Recruiting
Eye-tracking study of attention to faces after jaw surgery
This trial uses eye-tracking to measure how people look at faces after jaw surgery (orthognathic surgery). It is designed to help researchers understand changes in social attention following the procedure.
Amiens, PicardieAges 18 years+ - NCT06495866Recruiting
Ultrasound study of inflammation in spine and joint areas
This study uses ultrasound to look at inflammation where tendons and ligaments attach to bones in people with a type of arthritis called spondyloarthritis. It aims to understand these changes better, especially in those who also have fibromyalgia.
Sohag, Sohag GovernorateAges 19–60 - NCT06497140RecruitingPhase 3
Genicular artery embolization for painful knee osteoarthritis
This trial tests a new procedure called genicular artery embolization to treat knee pain from osteoarthritis. If you have moderate to severe knee pain and are not a candidate for knee replacement or other surgery, this treatment may help reduce pain and improve function.
ParisAges 40–90 - NCT06498167Recruiting
Rinvoq safety study
This study is checking the safety of the medicine Rinvoq (upadacitinib) in people who have been prescribed it. It involves answering a few questions over the phone to help doctors understand how the medicine is working for you.
PortoAges 18 years+ - NCT06500390Recruiting
TMD and levonorgestrel IUD use study
This study looks at whether using a levonorgestrel intrauterine device (a hormone-releasing IUD) for at least 3 months is linked to jaw joint problems (temporomandibular disorder). It may help women understand potential side effects of this birth control method.
Istanbul, MaltepeAges 18–45 - NCT06500364RecruitingPhase 4
Knotless implants for hip capsule closure study
This study tests a new knotless device for closing the hip capsule during hip arthroscopy. It may help patients heal better after surgery.
Des Plaines, IllinoisAges 18–60
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.