Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT06686719Recruiting
Stretching and relaxation for kids with spastic cerebral palsy
This trial compares three gentle stretching and muscle relaxation techniques to see which one best helps children with spastic cerebral palsy move more easily and feel less stiff. The goal is to find a safe, non-invasive way to improve daily function.
RawalpindiAges 8–18 - NCT06686732Recruiting
Multimodal rehab for tennis elbow
This study tests a combination of treatments (multimodal rehabilitation) for people with tennis elbow (lateral epicondylitis) that has lasted at least 2 months. It aims to see if this approach helps reduce pain and improve function.
Wāh, Punjab ProvinceAges 18–45 - NCT06688214Recruiting
Kinesiology taping and shoulder exercises for shoulder pain
This trial tests if kinesiology taping (a special type of tape applied to the shoulder) plus exercises that strengthen the shoulder blades works better than just exercises alone for people with shoulder impingement syndrome (a common cause of shoulder pain). You may qualify if you have had pain on the front or side of your shoulder for at least 3 months and have certain positive tests from a physical therapist.
Lahore, Punjab ProvinceAges 18–55 - NCT06688851Recruiting
Custom implants for jaw cysts
This study tests custom-made implants to help treat jaw cysts that are near important structures. It may be an option for people whose cysts are in tricky locations where standard surgery might be risky.
Budapest, BudapestAges 18 years+ - NCT06690710RecruitingPhase 1
Gene therapy injection for knee osteoarthritis
This trial tests a new gene therapy injection for knee osteoarthritis. It aims to see if the treatment is safe and if it can help with knee pain and joint function in people with moderate knee osteoarthritis.
OxfordAges 40 years+ - NCT06692244Recruiting
Custom 3D-printed mesh for jawbone regrowth
This trial is testing a custom-made titanium mesh (built with a 3D printer) to help regrow bone in your jaw where teeth are missing. It may be an option if you have moderate to severe bone loss and need a strong foundation for dental implants.
Guangzhou, GuangdongAges 18–60 - NCT06692426RecruitingPhase 1
Cell therapy for Duchenne muscular dystrophy
This trial tests a new cell-based treatment for Duchenne muscular dystrophy in adults who can no longer walk. The goal is to see if the therapy can help improve muscle function.
Minneapolis, MinnesotaAges 18 years+ - NCT06693479Recruiting
Using a feedback device to help manage shoulder pain at work
This study tests whether a feedback device can help people with work-related shoulder pain manage their symptoms. You may qualify if you have shoulder pain from rotator cuff issues, arthritis, or rheumatoid arthritis and work full-time.
Québec, QuebecAges 18 years+ - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT06694532RecruitingPhase 1/Phase 2
Arthrocentesis with hyaluronic acid for TMJ disorders
This trial tests two types of hyaluronic acid (high vs low molecular weight) given during a jaw joint procedure (arthrocentesis) to see which better relieves pain and improves jaw function in people with TMJ disorders.
AsyutAges 18–100 - NCT06696027Recruiting
Loss of Y chromosome in autoimmune and lung disease
This study looks at how the loss of the Y chromosome in blood cells may be linked to autoimmune and lung diseases in older men. By joining, you help researchers understand this connection better.
Bonn, North Rhine-WestphaliaAges 50 years+ - NCT06696287Recruiting
6-minute hand and arm test in fibromyalgia
This study tests a simple 6-minute hand and arm exercise (pegboard and ring test) in people with fibromyalgia. It helps researchers understand how well you can use your hands and arms during daily activities.
KırşehirAges 18–65 - NCT06701474Recruiting
Knee replacement recovery: comparing body composition groups
This study looks at how well people recover after total knee replacement, comparing those with different body composition levels. The goal is to see if a measure called 'phase angle' affects recovery of strength and function.
Yongin-si, Gyeonggi-doAges 55 years+ - NCT06702046Recruiting
Pulsed radiofrequency acupuncture for knee osteoarthritis
This trial tests whether a special type of acupuncture using mild radiofrequency energy can reduce knee pain and improve function in people with knee osteoarthritis. It involves 4 weeks of treatment and a 3-month follow-up to see if the benefits last.
Taipei, StateAges 45–85 - NCT06702176Recruiting
Testing a multisite TENS suit for fibromyalgia symptoms
This trial tests a special suit that uses gentle electrical pulses to help reduce fibromyalgia pain and other symptoms. If you qualify, you might find new relief for your fibromyalgia.
Créteil, VAL DE MARNEAges 18–75 - NCT06703736Recruiting
Understanding leg function in multiple osteochondromas
This study aims to understand how multiple osteochondromas (bony growths that can form near joints) affect walking and leg function. It compares people with the condition to healthy volunteers, using motion analysis and imaging.
BolognaAges 6–40 - NCT06704061Recruiting
Online yoga vs ACT for chronic pain in veterans
This study compares online yoga with Acceptance and Commitment Therapy (ACT), a type of talk therapy, to see which helps veterans better manage long-lasting muscle or bone pain. You can join from home through the internet.
Palo Alto, CaliforniaAges 18 years+ - NCT06704893RecruitingPhase 3
Amniotic fluid injection for knee arthritis pain
This study tests if an injection made from amniotic fluid can reduce knee pain and improve function in people with moderate knee osteoarthritis. The goal is to give a long-lasting alternative to steroid or gel shots.
Kaohsiung, TaiwanAges 18–80 - NCT06704906Recruiting
Spine fusion surgery with a new bone graft material
This study tests a new bone graft material (Fibergraft BG Putty) used with a special screw system (Viper Prime) during spine fusion surgery. It is for adults with lower back problems who need 1 to 3 vertebrae fused, and who are not smokers or have a very low bone density.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06704919Recruiting
Spinal fusion using conduit cages and bone graft putty
This trial tests a new combination of a cage and bone graft putty for spinal fusion surgery. It is for people with degenerative disc disease or a herniated disc in the neck or lower back that needs surgery.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06706037Recruiting
Reformer exercise for chronic muscle and joint pain
This study tests if Reformer Pilates exercises can reduce pain for people with long-term muscle or joint pain. It may help you feel better and move more easily.
Ankara, Select StateAges 30–50 - NCT06707194RecruitingPhase 4
Penicillin plus etanercept for spondyloarthritis
This trial tests whether adding a common antibiotic (benzathine penicillin) to a standard biologic drug (etanercept) can better treat spondyloarthritis. It may help if you have active disease and are free of certain infections.
Hefei, AnhuiAges 18–59 - NCT06707532Recruiting
Muscle relaxants for safer heart rhythm treatment
This study tests if giving muscle relaxants before a heart ablation procedure can protect muscles from damage. Ablation uses energy to fix irregular heartbeats, and muscle relaxants might make it safer.
Wroclaw, Lower Silesian VoivodeshipAges 18–90 - NCT06341023Recruiting
Balance training for older adults with MS
This study tests a balance training program for people with MS who have mild walking and memory difficulties. It aims to improve balance and prevent falls.
Chicago, IllinoisAges 18–90
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.