Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07508553Recruiting
Bone density in third trimester: singleton vs. twin pregnancy
This study compares bone density in the third trimester between women pregnant with one baby versus twins. If you qualify, you'll fill out questionnaires and have a quick, non-invasive bone scan to help researchers understand how pregnancy affects bone health.
Roma, RMAges 30–45 - NCT07509021Recruiting
Shoulder impingement, pain thoughts, and treatment sticking
This study looks at how pain, thinking patterns, and sticking to treatment relate in people with shoulder impingement. It aims to help improve physical therapy programs by understanding these factors.
BoluAges 18–65 - NCT07509307RecruitingPhase 3
Study of a new medicine for weight loss and knee pain in osteoarthritis
This trial tests if a new medicine, NNC0487-0111, can help people with excess weight and knee osteoarthritis lose weight and reduce knee pain. It is for people who have had knee pain for at least three months and who can stop taking pain relievers for short periods before study visits.
Escondido, CaliforniaAges 18 years+ - NCT07509775Recruiting
Chinese medicine and Western medicine for Ankylosing Spondylitis
This study tests if combining traditional Chinese medicine with standard Western medicine can better treat ankylosing spondylitis. The goal is to see if this approach can reduce inflammation and improve your symptoms, such as back pain and stiffness.
Beijing, Beijing, ChinaAges 18–75 - NCT07510789Recruiting
Low back pain impact in ankylosing spondylitis
This study looks at how different types of low back pain in people with ankylosing spondylitis affect their daily functioning and overall well-being. It aims to better understand these pain patterns so doctors can provide more personalized care.
Konya, SelçukluAges 18 years+ - NCT07511751Recruiting
Comparing treatments for myofascial pain syndrome
This trial compares three different treatments to find which works best for long-term back pain caused by myofascial pain syndrome, a condition where tight muscle knots cause pain. It is for people who have not found relief with standard treatments.
Adapazarı, SakaryaAges 18–65 - NCT07512934Recruiting
Pancreatic Function Study in Early Type 2 Diabetes
This study examines how the pancreas works in people newly diagnosed with type 2 diabetes. Researchers will assess pancreatic function to better understand early diabetes and potentially improve treatment.
Aktobe, AktobeAges 18–74 - NCT07513350Recruiting
Exercise and anti-fibrotic treatment for frozen shoulder
This study tests whether exercise combined with an anti-fibrotic medication (a drug that reduces scar tissue) helps people with frozen shoulder regain shoulder movement. Frozen shoulder causes stiffness and pain that limits your ability to move your arm.
IstanbulAges 18 years+ - NCT07513415Recruiting
Injectable knee filler for osteoarthritis pain relief
This trial tests a new injectable filler called ALLOHEAL, injected directly into the knee joint to reduce pain and improve function in people with knee osteoarthritis. The filler is designed to cushion the knee joint and may help reduce pain and stiffness.
Uijeongbu-siAges 40–80 - NCT07515235Recruiting
DMD Gene Variants and Heart Function in Young Males
This study examines how different genetic changes in the DMD gene affect heart function in boys with dystrophinopathy (a muscle-weakening condition). Understanding this connection may help doctors better monitor and treat heart problems in affected boys.
ThessalonikiAges 2–24 - NCT07516067Recruiting
Spinal Cord Stimulation to Help Children With Cerebral Palsy Move Better
This study tests whether a mild electrical stimulation applied to the skin over the spine can help children with cerebral palsy improve their movement and walking. Researchers will compare children who receive this treatment with children who don't have cerebral palsy to see if it makes a real difference.
Pittsburgh, PennsylvaniaAges 5–17 - NCT07516652Recruiting
Comparing two surgical approaches for trigger finger
This trial tests two different surgical techniques for treating trigger finger, a condition where a finger gets stuck or clicks when you bend it. The study compares the outcomes of two ways surgeons can release the tight tissue causing the problem.
Chicago, IllinoisAges 18 years+ - NCT07517172Recruiting
Brain Stimulation Patch for Jaw Pain: Home Treatment Study
This study tests whether a small, stick-on electrical patch placed on your ear can reduce temporomandibular disorder (TMD) jaw pain when used at home. You would apply the patch yourself and complete surveys about your pain to help researchers learn if this non-invasive approach is safe and feasible.
Minneapolis, MinnesotaAges 18–65 - NCT07517250Recruiting
Study of Canakinumab for Fever and Joint Disease
This is a study looking back at patients who were already treated with a medicine called canakinumab for familial Mediterranean fever or Still's disease (rare conditions that cause fevers and joint pain). Researchers want to understand how well this medicine worked over time and what happened to patients who took it.
BaselAges 1 year+ - NCT07517575RecruitingPhase 2
Olokizumab for Children with Juvenile Idiopathic Arthritis
This trial tests a new medicine called olokizumab in children and teenagers with juvenile idiopathic arthritis (JIA)—a condition where the immune system causes joint inflammation and pain. The study checks if this drug is safe and effective for children whose arthritis hasn't improved enough with standard treatments.
Kazan'Ages 2–17 - NCT07518615Recruiting
Safety and Effectiveness of Guided Dental Implant Surgery System
This trial tests a new computer-guided system (Straumann Dynamic Navigation Falcon) that helps dentists place dental implants more precisely. If you need one or more dental implants and have healthy gums and jaw, this study may help determine if this guided approach is safe and works well.
GhentAges 18 years+ - NCT07520656Recruiting
Heart Valve Surgery and Sleep Breathing Problems
This study looks at whether fixing heart valve problems with minimally invasive procedures (TAVI or MTEER) can improve sleep-related breathing issues. Researchers will monitor your sleep patterns before and after your scheduled heart valve procedure.
Athens, AtticaAges 18 years+ - NCT07520721Recruiting
Shoulder Replacement Materials: Plastic vs Hybrid Implants
This trial compares two types of shoulder replacement implants for people with long-standing shoulder arthritis. It tests whether a hybrid design (combining different materials) works better than a traditional plastic design for pain relief and shoulder function.
Hoofddorp, North HollandAges 18 years+ - NCT07523399Recruiting
Joint Health and Balance in Adults with Hemophilia A
This study looks at how hemophilia A affects joint health, balance, and quality of life in adults. Researchers will assess your joints and balance to understand the relationship between joint damage and everyday function.
VanAges 18–65 - NCT07523893Recruiting
Shockwave therapy versus exercises for tennis elbow
This study compares two treatments for lateral epicondylitis (tennis elbow): shockwave therapy and eccentric exercises. It aims to see which approach works better for reducing pain and improving arm function.
IslamabadAges 20–50 - NCT07524244Recruiting
Ketogenic and carnivore diets for IBD and rheumatoid arthritis
This study tests whether special diets (ketogenic or carnivore/meat-based) can help reduce inflammation and symptoms in people with inflammatory bowel disease or rheumatoid arthritis. You'll follow dietary guidelines for 3 weeks, then continue in the study while researchers track how you respond.
Charlottesville, VirginiaAges 18–64 - NCT07525557Recruiting
Understanding Fear and Disability in Long-Term Neck Pain
This study explores how fear of movement, pain, and daily difficulties relate to each other in people with chronic neck pain lasting 3+ months. Understanding these connections may help improve future treatment approaches.
Samsun, SamsunAges 18 years+ - NCT07525921Recruiting
Dry Needling for Calf Pain in Amateur Football Players
This study tests whether dry needling—inserting thin needles into tight muscle knots in the calf—can reduce pain and improve running speed and performance in young football players. Researchers want to see if this treatment helps athletes play better and feel less discomfort.
Islamabad, Punjab ProvinceAges 18–25 - NCT07526129Recruiting
Ridge Preservation After Back Tooth Extraction
This study looks at whether a procedure called ridge preservation, done after removing upper back teeth, helps prevent the need for sinus bone grafting later. Researchers will compare patients who had this procedure with those who didn't, using 10 years of X-ray records.
Beirut, BeirutAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.