Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07548034Recruiting
Ultrasound-Guided Treatment for Hip Pinching Pain
This trial tests a minimally invasive needle treatment combined with exercise for hip pain caused by tissue tightness near the hip joint. The treatment uses ultrasound imaging to guide a small needle that delivers electrical energy to reduce scar-like tissue, plus physical therapy to improve hip function.
Alcobendas, MadridAges 18–55 - NCT07550543Recruiting
PEMF Therapy for Chronic Shoulder Pain
This study tests whether pulsed electromagnetic field (PEMF) therapy—a treatment using magnetic pulses—can reduce chronic shoulder pain and improve how well your shoulder works. You would receive this therapy at a rehabilitation center over several weeks.
Constanța, TechirghiolAges 18–70 - NCT07551024Recruiting
Zygomatic Implant Placement Accuracy: Metallic vs Resin Guides
This study compares two types of surgical guides (metallic and resin-based) to help dentists place zygomatic implants—special dental anchors used when the upper jaw bone is severely worn down. The goal is to see which guide method places these implants more accurately.
New Cairo, Cairo GovernorateAges 18 years+ - NCT07551999Recruiting
Voice Analysis Tool for ME/CFS Diagnosis and Monitoring
This study tests a smartphone app that analyzes your voice to help diagnose and track myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)—a condition causing extreme tiredness and other symptoms. Researchers want to see if voice patterns can be a simple, at-home way to monitor your condition over time.
Rochester, MinnesotaAges 18 years+ - NCT07552519Recruiting
Patient Outcomes in Spinal Disease Treatment
This study tracks how patients feel and function after receiving treatment for spinal disease (which may include procedures like spinal cord stimulation). Researchers want to understand what matters most to patients during their recovery.
Hasselt, LimburgAges 18 years+ - NCT07553182RecruitingPhase 3
Continuing filgotinib treatment for juvenile arthritis
This study lets young people who benefited from filgotinib (a medication that reduces inflammation) in a previous trial continue taking it to see if it stays safe and effective over a longer period. It's designed for patients ages 8–17 who did well on this medicine before.
Le Kremlin-BicêtreAges 8–18 - NCT07553351RecruitingPhase 3
Growth hormone treatment for children with growth hormone deficiency
This trial tests a new growth hormone medicine (GB06) for children whose bodies don't make enough growth hormone naturally. The study will see if this treatment helps children grow taller over time.
Chengdu, SichuanAges 3–11 - NCT07554092Recruiting
Fast vs. Standard Casting for Baby Club Foot Treatment
This study compares two ways of treating club foot (a condition where a baby's foot is twisted inward at birth) using casts: a faster method and the traditional method. It will measure which approach works better using X-rays to see how well the foot straightens.
Peshawar, KPKAges 1 day–5 months - NCT07554495RecruitingPhase 3
Filgotinib for moderate to severe polyarticular juvenile arthritis
This trial tests filgotinib, a new medication that may help reduce joint swelling and pain in children and teens (ages 8–17) with polyarticular juvenile idiopathic arthritis—a type of childhood arthritis affecting multiple joints. You're eligible if your current arthritis medicines haven't worked well enough.
LeuvenAges 8–18 - NCT07554664Recruiting
Desk Work, Stress, and Muscle Pain With or Without Migraine
This study looks at how office work, job stress, and muscle tension relate to migraines and neck/shoulder pain in desk workers. Researchers want to understand if certain body changes (called central sensitization) connect these issues, which could lead to better ways to help office workers feel better.
Gaziantep, MerkezAges 18–65 - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT07555691Recruiting
Chinese herbal medicine for fibromyalgia pain relief
This trial tests whether a traditional Chinese herbal medicine called Yishen Shujin Decoction can reduce fibromyalgia pain. Fibromyalgia is a condition causing widespread body pain and fatigue; this study aims to see if this herbal treatment helps relieve those symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT07556003Recruiting
Physical Therapy After Knee Replacement Surgery
This study tests whether a physical therapy program helps improve walking ability and foot pressure patterns in women who have had knee replacement surgery or have knee problems. The goal is to see if structured rehabilitation helps you walk better and more comfortably.
SakakahAges 40–70 - NCT07556042Recruiting
Machine Learning to Predict Scoliosis Progression in Teens
This study uses artificial intelligence to predict how adolescent scoliosis (curvature of the spine) might progress over time. By understanding which teens are most at risk, doctors hope to catch and treat the condition earlier.
Istanbul, EyupsultanAges 10–18 - NCT07556224Recruiting
Combining Chinese and Western Medicine for Ankylosing Spondylitis
This study tests whether combining traditional Chinese medicine with standard Western treatments can help ankylosing spondylitis (a condition causing spine stiffness and inflammation) work better and improve your quality of life. Researchers will follow patients over time to see how well this combined approach works.
Beijing, Beijing MunicipalityAges 18–75 - NCT07556874Recruiting
Study of Surgeries for Multiple Bone Tumors
This research looks at surgery records from patients who had multiple osteochondromas (benign bone tumors) treated at a major orthopedic hospital. The study aims to understand what surgical approaches work best for this condition.
Bologna, BolognaAges Any age - NCT07557446RecruitingPhase 2
Testing AGA2115 for Osteogenesis Imperfecta in Chinese Patients
This study tests a new medicine called AGA2115 in adults and teenagers with osteogenesis imperfecta (brittle bone disease). The trial aims to find the right dose and see if it can strengthen bones and reduce fracture risk.
Beijing, Beijing MunicipalityAges 12–75 - NCT07558564Recruiting
Platelet-Rich Plasma Treatment for Chronic Tendon Pain
This trial tests whether an injection of concentrated platelets from your own blood can help heal chronic tendon injuries that haven't improved with other treatments. Platelets contain natural healing factors that may reduce pain and improve function.
A CoruñaAges 18 years+ - NCT07558590Recruiting
Shoulder Replacement System Recovery and Function Study
This study follows patients who have received a new shoulder replacement device to see how well it works and how patients recover. Researchers will collect information about your shoulder function and satisfaction over time.
AmiensAges 18 years+ - NCT07558850Recruiting
CAR-T Cell Therapy for Treatment-Resistant Autoimmune Diseases
This study tests a new type of immune cell therapy (CAR-T cells) designed to treat severe autoimmune diseases like rheumatoid arthritis, lupus, dermatomyositis, and scleroderma that haven't responded well to standard treatments. The therapy works by modifying your own immune cells to target and eliminate the B cells that are causing your autoimmune disease.
Nanjing, JiangsuAges 18–70 - NCT07561255Recruiting
Testing a digital health app for everyday use and satisfaction
This study evaluates how well patients accept and use Axia, a digital health app designed for specific health conditions. Researchers want to understand if a 14-day trial period helps patients decide whether the app is right for them.
Würzburg, BavariaAges 18 years+ - NCT07561697Recruiting
Achilles Tendon Surgery Options for Clubfoot in Young Children
This study compares two surgical approaches to lengthen the Achilles tendon (the cord at the back of the heel) in young children with clubfoot—a condition where the foot is twisted inward and downward. The goal is to find which method works better and causes fewer complications.
Karachi, SindhAges 2–5 - NCT07563777Recruiting
Long-term study of human aging and health
This is a long-term research study that follows people over time to understand how humans age. Researchers will collect information about your health and lifestyle to learn what helps people stay healthier as they get older.
Boulder, ColoradoAges 18 years+ - NCT07564713Recruiting
Shock Wave vs. Laser Therapy for Tennis Elbow
This study compares two non-surgical treatments for tennis elbow (lateral epicondylitis): extracorporeal shock wave therapy and low-level laser therapy. Both treatments aim to reduce pain and improve function in people with chronic elbow pain caused by overuse.
ÇorumAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.