Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,843 recruiting studies in this area right now.
By phase
- Not applicable3,974
- Phase 2225
- Phase 4197
- Phase 1190
- Phase 3149
- Phase 1/Phase 275
- Phase 2/Phase 333
Top conditions
- Knee Osteoarthritis184
- Rheumatoid Arthritis140
- Fibromyalgia102
- Osteoporosis86
- Osteoarthritis74
- Osteoarthritis, Knee71
- Rheumatoid Arthritis (RA)66
- Shoulder Pain50
- Psoriatic Arthritis47
- Hip Osteoarthritis41
- Systemic Lupus Erythematosus41
- Duchenne Muscular Dystrophy39
- Degenerative Disc Disease38
- Chronic Pain37
- Total Knee Arthroplasty37
- Musculoskeletal Pain36
- Pain35
- Dermatomyositis31
Leading sponsors
- Riphah International University111
- Cairo University72
- Istituto Ortopedico Rizzoli71
- Assistance Publique - Hôpitaux de Paris37
- Foundation University Islamabad33
- Mayo Clinic29
- Massachusetts General Hospital27
- National Taiwan University Hospital25
- Chinese University of Hong Kong22
- Hacettepe University22
Where studies are running
- California211
- New York94
- Florida82
- Massachusetts76
- Arizona75
- Maryland73
- Texas65
- Alabama57
- Illinois55
- Pennsylvania50
Recruiting studies4,843 total
- NCT07565636Recruiting
Custom 3D-Printed Wrist Support for Ehlers-Danlos Syndrome
This trial tests a custom-made wrist brace designed with 3D printing technology to help stabilize loose, overly flexible wrists in people with Ehlers-Danlos syndrome. The goal is to see if this personalized support can improve wrist function and reduce pain or instability.
Lowell, MassachusettsAges 21 years+ - NCT07566351RecruitingPhase 2
Add-On Drugs for Rheumatoid Arthritis
This study tests whether two drugs—roflumilast and desloratadine—added to your current rheumatoid arthritis medications can reduce joint inflammation and pain. You'd take these as add-ons to your existing treatment to see if they help control your disease better.
Damietta, Damietta GovernorateAges 18–60 - NCT07567807Recruiting
Understanding Tests for Chronic Heel Pain
This study evaluates the best ways to diagnose and measure chronic heel pain (plantar fasciitis) in patients considering surgery. By comparing patients with long-lasting heel pain to those without foot problems, researchers aim to improve how doctors identify and assess this condition.
Bologna, BOAges 18–18 - NCT07568340Recruiting
Supervised versus home exercises for shoulder impingement
This trial compares two ways to treat subacromial impingement syndrome (a common shoulder condition causing pain with overhead movements): supervised rehabilitation sessions versus exercises you do at home. The goal is to see which approach works better for reducing pain and improving shoulder function.
Kırşehir, KırşehirAges 30–65 - NCT07569731Recruiting
Understanding Fibrous Dysplasia Through Patient Data and Tissue
This study collects information from patients with fibrous dysplasia (a bone condition where normal bone is replaced by fibrous tissue) and related syndromes to better understand the disease. Researchers will review your medical records, imaging scans, and stored tissue samples to learn more about how the disease develops and progresses.
Bologna, BOAges Any age - NCT07569848Recruiting
Custom ankle replacement for severe bone loss
This study tests a custom-designed ankle replacement device for people with severe ankle bone damage or loss. The device is made specifically for each patient at the Rizzoli Institute in Italy to help restore ankle function and reduce pain.
BolognaAges 35–75 - NCT07569835Recruiting
Long-Term Outcomes of Childhood Flatfoot Surgery
This study follows up with patients who had surgery to correct flat feet in childhood using special implants. Researchers want to see how well the surgery worked over 10 years and whether any changes occurred in the foot structure.
BolognaAges Any age - NCT07571122Recruiting
Brain Training to Help Heel Pain and Balance
This study tests whether cognitive training (exercises that challenge your thinking and memory) combined with physical exercises can reduce heel pain, improve balance, and strengthen foot function in people with plantar fasciitis. The goal is to see if training your brain alongside your body helps more than physical therapy alone.
CairoAges 18–60 - NCT07571993Recruiting
Tracking Rheumatoid Arthritis Remission and Treatment Changes
This study follows people with rheumatoid arthritis (RA) who have achieved remission—meaning their disease is well-controlled—to see how safely doctors can reduce or stop their medications over time. You would be monitored regularly to ensure your RA stays in remission.
Pavia, PaviaAges 18 years+ - NCT07574385RecruitingPhase 2
Nerve Block Pain Relief After Bunion Surgery
This study tests a new nerve-blocking medication (ALX006) injected near the sciatic nerve to reduce pain after bunion surgery. The goal is to see if it provides better pain relief compared to standard care.
Millcreek, UtahAges 18 years+ - NCT07574632Recruiting
Testing a New Scoliosis Brace for Growing Kids
This study tests a new brace called RESILIENT designed to help prevent scoliosis curves from getting worse in children. You'll wear the brace and the research team will track whether it helps slow or stop curve progression.
Wilmington, DelawareAges 9–16 - NCT07574606Recruiting
Soft Tissue Coverage for Zygomatic Implants in Jaw Bone Loss
This study compares two surgical methods to cover zygomatic implants (special anchor posts for teeth) in patients with severe jawbone loss. Researchers will measure how much soft tissue (gum and fat) builds up over the implants to see which method produces better, longer-lasting results.
Cairo, New CairoAges 18 years+ - NCT07574762Recruiting
Knee Replacement: Computer Navigation vs. Robotic Surgery
This study compares two advanced surgical techniques for knee replacement in patients with knee arthritis. Researchers want to see if robotic-assisted surgery offers any advantages over computer-guided navigation surgery for placing the artificial knee.
Paris, ParisAges 18 years+ - NCT07575009RecruitingPhase 3
Home-based continuous antibiotic infusion for children
This study tests whether children can safely receive antibiotics continuously through a pump at home instead of in the hospital. The goal is to help children recover while staying with their family and avoiding prolonged hospital stays.
TampereAges Up to 16 years - NCT07575425Recruiting
Balance Platform Exercises for Knee Osteoarthritis
This study tests whether special balance exercises on a moving platform can improve steadiness and walking in people with moderate knee osteoarthritis. The goal is to see if this type of training helps reduce pain and improve mobility.
AnkaraAges 45–65 - NCT07576127Recruiting
Gongs Mobilization and Stretching for Frozen Shoulder
This study tests two hands-on treatment techniques—gongs mobilization and proprioceptive neuromuscular facilitation (a type of guided stretching)—to help reduce stiffness and improve movement in frozen shoulder. Frozen shoulder causes pain and loss of motion in the shoulder joint; this trial aims to see if these treatments can help restore function.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07576504Recruiting
Physical therapy technique for flat feet in children
This study tests whether a special movement-based technique can help reduce flat feet in school-age children. Flat feet can affect how kids walk and play, and this therapy may help improve foot arch height.
Lahore, Punjab ProvinceAges 7–12 - NCT07576816Recruiting
Hip vs. Knee Exercises for Flat Feet
This study compares two types of exercises—one focusing on hip muscles and one on knee muscles—to see which better improves flat feet, balance, and leg strength. If you have flexible flat feet without pain, this trial may help you strengthen your feet and improve stability.
Faisalābad, Punjab ProvinceAges 25–40 - NCT07576829Recruiting
Wrist and shoulder exercises for tennis elbow pain
This study tests whether specific wrist and shoulder exercises can reduce pain and improve grip strength in people with tennis elbow (pain on the outside of the elbow). You'd do resistance exercises and stabilization work to see if they help you regain function.
SādiqābādAges 30–50 - NCT07578220Recruiting
New Acupotomy Method for Ankylosing Spondylitis
This trial tests a new acupuncture-based procedure called acupotomy to help people with ankylosing spondylitis (a condition that causes spine stiffness and pain). The study aims to see if this improved technique reduces pain and improves mobility.
Henan, ZhengzhouAges 18–75 - NCT07578610Recruiting
Registry study of symptom descriptions using OpenGenome platform
This is an observational registry study that collects and analyzes symptom descriptions from patients using the OpenGenome platform. The goal is to better understand and extract health information from how people naturally describe their symptoms.
Friedrichshain, State of BerlinAges 18 years+ - NCT07578831Recruiting
Neck Pain Relief: Comparing Two Exercise Methods
This study compares two types of therapeutic exercises—Kendall and Feldenkrais—to help reduce neck pain and improve posture in people with upper crossed syndrome (a common postural condition where neck and shoulder muscles become tight and weak). You'll do one type of exercise program to see which helps your neck pain and function better.
Lahore, Punjab ProvinceAges 20–50 - NCT07578974Recruiting
Foot-Strengthening Training for Children with Flat Feet
This study tests whether special exercises that strengthen the small muscles in your child's foot—with or without visual feedback on a screen—can improve flat feet and balance in children ages 7–12. Flat feet are common in kids and usually improve on their own, but this trial explores whether targeted training helps.
Lahore, Punjab ProvinceAges 7–12 - NCT07579585Recruiting
Light therapy for knee bleeding in hemophilia children
This study tests whether a special type of light therapy (photobiomodulation) can help reduce pain and swelling in the knees of children with hemophilia who experience bleeding into the joint. Hemophilia is a bleeding disorder where blood doesn't clot properly.
Sialkot, Punjab ProvinceAges 9–14
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,843 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,987 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.