Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07759362RecruitingPhase 3
Study of a new treatment for flexible hammertoe
This trial tests an investigational treatment called KN3835 for flexible or semi-flexible hammertoe, a condition where one of your toe joints bends downward. The treatment is given as an injection and may help straighten the toe and reduce pain.
Corona, CaliforniaAges 18–75 - NCT07766395Recruiting
Daily powder for women's wellness and fitness
This trial tests a daily powder supplement designed to support lean muscle, hormone balance, digestion, and skin, hair, and nail health. If you're an active woman with some common wellness concerns, this study may help you see if the supplement makes a difference.
Las Vegas, NevadaAges 21–45 - NCT07766720Recruiting
Eggshell membrane and turmeric supplements for exercise recovery
This trial tests whether taking eggshell membrane, curcumin (turmeric), or both together can help your muscles recover faster after intense exercise. It may reduce soreness and help you bounce back sooner.
College Station, TexasAges 18–40 - NCT07765082Recruiting
Textured insoles for foot function in plantar fasciopathy
This trial tests whether textured shoe insoles can improve foot function and reduce pain in people with long-standing plantar fasciopathy (a common cause of heel pain). You may join if your condition has lasted at least 3 months and you can walk for 20 minutes, but you must be otherwise healthy without recent leg injuries or other balance issues.
Lexington, KentuckyAges 18–55 - NCT07760142Recruiting
Electrical stimulation with core exercise for chronic low back pain
This study tests whether adding electrical stimulation to a core exercise program helps relieve chronic low back pain. You would attend two sessions a week for six weeks.
ŞırnakAges 18–55 - NCT07766031Recruiting
Comparing endoscopic and open surgery for herniated disc pain
This study compares two types of surgery for a herniated disc in the lower back: endoscopic (using a small camera) and open surgery. It aims to see which approach leads to less pain and less need for painkillers after the operation.
Saint-GrégoireAges 18 years+ - NCT07761780Recruiting
Comparing two surgical approaches for tibia fracture repair
This study compares two ways surgeons reach the tibia bone during a procedure to fix a broken shinbone (tibia) with a metal rod. It aims to find which method leads to better recovery of leg function.
Lahore, Punjab ProvinceAges 18–60 - NCT07765173Recruiting
Muscle function after ACL reconstruction in active people
This study looks at how well your thigh muscles work after ACL reconstruction surgery. It aims to understand muscle power recovery in active people, which could help improve rehabilitation programs.
Challes-les-EauxAges 18–65 - NCT07760662Recruiting
Oxidative stress and heart risk in rheumatoid arthritis
This study looks at how oxidative stress (an imbalance of harmful molecules in the body) relates to cardiovascular risk in people with rheumatoid arthritis. It aims to see if these factors are linked, which could help in better managing heart health for RA patients.
Santa Cruz de Tenerife, Canary IslandsAges 18 years+ - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07763327Recruiting
Wearable device and app for posture in university students
This study tests whether using a wearable posture belt, a phone app, and simple exercises can improve posture in university students. If you sit a lot and notice postural issues, this may help improve your neck, shoulder, and back alignment.
IslamabadAges 18–30 - NCT07763158Recruiting
Treatment for severe knee pain using artery embolization
This study tests a procedure that blocks tiny arteries in the knee to reduce pain from severe arthritis. It is for people who cannot have knee replacement surgery because of other health issues.
Jeddah, Mecca RegionAges 18 years+ - NCT07763522Enrolling by invitation
Measuring ankle strength in people with herniated disc weakness
This study tests a new way to measure ankle strength in people who have weakness from a herniated disc in the lower back. The goal is to confirm the measurement tool works well for tracking such weakness.
Helsinki, UusimaaAges 18–65 - NCT07758712Recruiting
Horse riding simulator for teens with scoliosis
This study tests whether using a horse riding simulator can help improve posture and reduce spine curvature in teenagers with scoliosis. It may be a fun and safe way to support your treatment.
IstanbulAges 10–19 - NCT07766980RecruitingPhase 2
Nutritional supplement for quality of life in Duchenne muscular dystrophy
This study tests whether a daily nutritional supplement called VM100 can improve quality of life for people with Duchenne muscular dystrophy. If you are 8 or older and your medications have been stable for at least 3 months, you may be able to participate.
Gainesville, FloridaAges 6 years+ - NCT07763080Recruiting
Shoulder exercise for pain after breast cancer treatment
This study tests if a specific shoulder exercise can reduce pain from a common side effect of breast cancer treatment. It may help women who have had a mastectomy and are taking aromatase inhibitors.
CairoAges 50–70 - NCT06581562RecruitingPhase 1
Testing rituximab plus AB-101 for autoimmune diseases
This trial tests a new treatment (AB-101) combined with rituximab for people with certain autoimmune diseases like rheumatoid arthritis, pemphigus vulgaris, vasculitis, or lupus. It is for those who have not had success with standard therapies.
Plantation, FloridaAges 18 years+ - NCT06581978Recruiting
Early warning for foot health in children
This study looks at the health of children's feet and aims to spot early signs of foot problems. It may help guide how to prevent issues like flat feet.
Guangzhou, GuangdongAges 6–18 - NCT05569161Recruiting
Testing a shoulder replacement called Embrace for 2 years
This study looks at how safe an Embrace reverse shoulder replacement is over two years and what results you can expect on imaging scans. You may qualify if you’re an adult with a shoulder problem that can be treated with this specific type of replacement and have recent CT or MRI scans.
MadridAges 18 years+ - NCT06258369Recruiting
How people with hip arthritis start walking
This study looks at how people with hip arthritis begin to walk and shift their weight from one leg to the other. It aims to understand movement changes before hip replacement surgery.
LilleAges 18 years+ - NCT07752849Recruiting
Platelet-rich fibrin gel for cleft palate repair
This study compares two types of gel made from the patient's own blood, with or without an antibiotic, applied during cleft palate surgery to see if they improve healing and reduce complications.
SanaaAges 3 months–18 years - NCT07756203Recruiting
Comparing two hand-held treatments for shoulder pain
This study tests two non-surgical treatments for shoulder pain caused by shoulder impingement. Both treatments use hand-held tools to ease pain and improve movement.
Istanbul, BeykozAges 40–60 - NCT07753122Recruiting
Hydrogen water for chronic fatigue syndrome
This trial tests whether drinking hydrogen water can help with symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). If you have ME/CFS, this study might show if hydrogen water is a helpful treatment.
Stony Brook, New YorkAges 18–65 - NCT07751718Recruiting
Pilates for office workers
This study tests whether Pilates exercises can help office workers feel better and reduce any pain or discomfort from sitting at a desk all day. If you work in an office, you might be able to join and try Pilates as part of the study.
ElâzığAges 18–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.