Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07750379Recruiting
Acid-reducing medicine for aspiration in children with laryngomalacia
This study tests whether giving a common acid-reducing medicine (a proton pump inhibitor) to children with laryngomalacia can reduce choking and aspiration. It may help if your child has frequent choking episodes.
Minya, Minya GovernorateAges 6 months–5 years - NCT07756125Recruiting
Stretching exercises for neck pain from smartphone use
This study compares two types of exercises for people with neck pain from using smartphones. One is a hands-on technique by a therapist, and the other is exercises guided by an app on your phone. It aims to see which works better for reducing pain and improving neck function.
Kallar Kahār, Punjab ProvinceAges 18–30 - NCT07753291Recruiting
Yi Jin Jing exercise for muscle and bone health in adults
This study looks at whether a special exercise routine called Yi Jin Jing (a type of traditional Chinese exercise) can help improve muscle and bone health in adults. It might be good for you if you are mostly healthy and want to try a gentle exercise program.
BeijingAges 18–90 - NCT07752849Recruiting
Platelet-rich fibrin gel for cleft palate repair
This study compares two types of gel made from the patient's own blood, with or without an antibiotic, applied during cleft palate surgery to see if they improve healing and reduce complications.
SanaaAges 3 months–18 years - NCT07756229Recruiting
Physiotherapy for long-term neck pain
This study looks at how physiotherapy affects brain activity and symptoms in people with chronic neck pain lasting more than 3 months. It aims to see if physiotherapy can help reduce pain and improve function.
San Sebastián, GuipuzcoaAges 18 years+ - NCT07756307Recruiting
Shock wave therapy for calcium deposits in the shoulder
This trial tests whether a non-invasive treatment called shock wave therapy can reduce pain and improve function in people with calcium deposits in the shoulder tendon. It uses sound waves to break up the deposits, which may relieve pain and help you move better.
Taipei, TaipeiAges 20–70 - NCT07751718Recruiting
Pilates for office workers
This study tests whether Pilates exercises can help office workers feel better and reduce any pain or discomfort from sitting at a desk all day. If you work in an office, you might be able to join and try Pilates as part of the study.
ElâzığAges 18–65 - NCT07753122Recruiting
Hydrogen water for chronic fatigue syndrome
This trial tests whether drinking hydrogen water can help with symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). If you have ME/CFS, this study might show if hydrogen water is a helpful treatment.
Stony Brook, New YorkAges 18–65 - NCT07754175Recruiting
Stem cell knee treatment for osteoarthritis patients
This study tests a stem cell injection for knee osteoarthritis in patients who previously received a placebo. It aims to see if the treatment is safe and effective over a longer period.
SeoulAges 19 years+ - NCT07756658Recruiting
Tyrosol and creatine for exercise and thinking
This trial tests whether taking two supplements, tyrosol and creatine, can improve how well you exercise and think. If you join, you'll take these supplements while keeping your usual workout and diet, and the researchers will measure changes in your performance and memory.
Tampa, FloridaAges 20–55 - NCT06590701Recruiting
Wrist ligament surgery rehab: early motion study
This study compares two different ways of moving the wrist after surgery to repair a specific wrist ligament (the scapholunate ligament). The goal is to see which type of early motion leads to better recovery.
Zurich, Canton of ZurichAges 18 years+ - NCT06587724Recruiting
Testing a questionnaire for myositis
This study is testing a new questionnaire called the BETY-BQ to see if it is a good tool for measuring how well people with myositis are doing—things like symptoms and function. The goal is to make it easier for doctors to track your progress over time.
Ankara, AltındağAges 18 years+ - NCT06593041Recruiting
Platelets in lupus and other autoimmune diseases
This study looks at how platelets (small blood cells that help with clotting) might play a role in autoimmune diseases like lupus. By understanding this, researchers hope to find new ways to treat these conditions.
Strasbourg, FranceAges 18–70 - NCT05868863Recruiting
Cement procedure for pelvic bone lesions with or without screws
This trial reviews a procedure that uses bone cement to treat a lesion in the pelvis, sometimes with added screw support. It aims to understand outcomes for patients having cement treatment, with or without screws.
Saint-EtienneAges 80 years+ - NCT07745712Recruiting
Testing a robotic exoskeleton for children with walking difficulties
This trial tests a robotic exoskeleton called ABLE Kids to help children with walking difficulties due to neurological or muscle conditions. It checks if the device is safe and works well. Children who meet certain size and health requirements may be eligible to participate.
Girona, GironaAges Up to 17 years - NCT07748624RecruitingPhase 2
Testing a new drug for people with VEXAS
This study tests an investigational drug called arumakimig (MAS825) in people with VEXAS, a rare genetic condition that causes inflammation. The trial checks if the drug helps control symptoms and improve quality of life.
Yokohama, KanagawaAges 18 years+ - NCT07744659Recruiting
Spinal cord stimulation for stroke-related muscle stiffness
This trial tests a spinal cord stimulator to reduce muscle stiffness (spasticity) after a stroke. If you've had arm or leg tightness that hasn't improved with other treatments, this device might help you move more easily.
BeijingAges 18–75 - NCT07748728Enrolling by invitationPhase 2
Study of TLL-018 for rheumatoid arthritis after standard treatments fail
This study tests an investigational drug called TLL-018 for people with moderate to severe rheumatoid arthritis who have not improved enough with standard disease-modifying drugs. It aims to see if the drug can reduce joint pain and swelling.
Beijing, Beijing MunicipalityAges 18–70 - NCT07749066Recruiting
Laser treatment for hip pain
This study tests a high-intensity laser treatment to reduce hip pain and improve function in people with greater trochanteric pain syndrome (pain on the outside of the hip). It may help if you've had hip pain for at least 3 months and haven't had recent injections or other conservative treatments.
Ankara, YenimahalleAges 18–80 - NCT06594107Recruiting
A study on early axial spondylitis
This study looks at people who have just been diagnosed with a type of arthritis that affects the spine (axial spondyloarthritis) and have not yet started treatment. The goal is to understand the disease better.
Huddinge, Stockholm CountyAges 18 years+ - NCT06608134RecruitingEarly Phase 1
Umbilical cord injection for knee osteoarthritis pain
This trial tests whether a special injection made from umbilical cord tissue can safely help with knee osteoarthritis pain. If you have moderate knee arthritis and haven't had recent injections or surgery, you may be able to join.
Scottsdale, ArizonaAges 30 years+ - NCT07745218Recruiting
Testing a new companion therapy for LAMA2 muscular dystrophy
This study looks at a new protein that might help people with LAMA2-related muscular dystrophy. It uses stored samples to see if the protein could be a useful addition to future treatments.
MilanAges Any age - NCT07748793Recruiting
Fat grafting for treating chronic tendon pain
This trial injects your own fat into the painful tendon area to help it heal. It is for people with long-lasting tendon pain that has not improved with other treatments like physical therapy or injections.
New York, New YorkAges 18–80 - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.