Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07745218Recruiting
Testing a new companion therapy for LAMA2 muscular dystrophy
This study looks at a new protein that might help people with LAMA2-related muscular dystrophy. It uses stored samples to see if the protein could be a useful addition to future treatments.
MilanAges Any age - NCT07749534Recruiting
Living with spinal deformity: quality of life study
This study follows adults with spinal deformity to understand how the condition and its treatments affect daily life, emotions, and physical function. It aims to improve care and support for people like you.
LeuvenAges 18 years+ - NCT07742397Recruiting
Leg strength and balance in adults over 65
This study looks at how differences in strength and function between your left and right legs might affect your risk of falling. If you join, you'll help researchers understand why some older adults fall and others don't, which could lead to better fall prevention.
Milan, MilanAges 65 years+ - NCT07749547Recruiting
Personalized exercise program for polymyalgia rheumatica
This study tests a personalized rehabilitation program to help people with polymyalgia rheumatica (PMR) become more active and reduce disease symptoms. It aims to see if tailored exercise can improve your condition and daily life.
St Louis, MissouriAges 50 years+ - NCT07744542Enrolling by invitation
Physical therapy for shoulder arthritis pain
This study tests if a specific physical therapy program can help people with shoulder arthritis (wear-and-tear in the shoulder joint) feel better and move more easily without surgery. It may help you if you have this type of arthritis and have not tried physical therapy recently.
Buffalo, New YorkAges 18 years+ - NCT07746284Enrolling by invitation
Understanding knee osteoarthritis through computer modeling
This study looks at how knee osteoarthritis pain works and aims to build a computer model to better understand it. By joining, you may help doctors improve future treatments for chronic knee pain.
Herndon, VirginiaAges 18–99 - NCT07744789Recruiting
Knee ligament stiffness and osteoarthritis treatment
This study looks at how knee ligament stiffness changes in people with knee osteoarthritis and compares it to healthy volunteers. It may help find better ways to treat knee pain and stiffness.
Taipei, Taipei CityAges 20 years+ - NCT07741227Recruiting
Electric acupuncture for chronic neck pain
This study tests whether electric acupuncture can reduce stiffness and pain in the neck muscles. It may be a treatment option if you have had neck pain for at least 3 months and would like to try a non-drug approach.
Hong KongAges 18–65 - NCT07745426RecruitingPhase 2
Comparing add-on treatments for rheumatoid arthritis
This trial compares two additional medicines (diosmin or rebamipide) taken with standard arthritis treatment to see if they help reduce joint pain and swelling better than standard treatment alone.
TantaAges 18–70 - NCT03643926Recruiting
Arthroscopic vs open surgery for ankle instability
This trial compares two surgical approaches to treat ongoing ankle “giving way” or instability. It aims to find which method works better for people whose ankle instability has lasted at least several months.
Belo Horizonte, Minas GeraisAges 18–65 - NCT06613295Recruiting
Spine cancer trial: Surgery plus radiation vs radiation alone
This trial compares two treatments for cancer that has spread to the spine: surgery followed by precise radiation versus radiation alone. It aims to see if adding surgery improves pain, movement, and quality of life.
AalstAges 18 years+ - NCT06028646Recruiting
Using CT scans to diagnose airway collapse in children
This trial tests if a special CT scan can help diagnose tracheomalacia (a condition where the airway collapses during breathing) in children who have already had a bronchoscopy.
New York, New YorkAges birth–18 years - NCT02979951Recruiting
IV fosfomycin for serious bacterial infections
This trial studies whether IV (through a vein) fosfomycin can treat severe bacterial infections in adults. It may help people whose infection is covered by the standard fosfomycin use and who need hospital-level care.
Hall in TirolAges 18 years+ - NCT04238143Recruiting
Knee and other joint arthritis tissue therapy
This trial tests a regenerative therapy made from a patient’s own fat tissue (a “cellular” treatment) to reduce pain and improve function in arthritis-related problems. It may help people with inflammatory or degenerative arthritis changes, if they meet safety and tissue-donation requirements.
Valencia, CaliforniaAges 18–90 - NCT05447819Recruiting
Shoulder replacement for worn rotator cuff joint
This trial studies a specific type of reverse shoulder implant to improve shoulder function after severe joint wear. It’s for people whose shoulder pain and loss of function did not improve enough with non-surgical treatments and who need shoulder arthroplasty.
Hellerup, DenmarkAges 50 years+ - NCT07733739Recruiting
Mandala coloring for pain, fatigue, and sleep in fibromyalgia
This trial tests whether coloring mandalas can help reduce pain, fatigue, and improve sleep in people with fibromyalgia. You will be asked to color mandalas regularly and report how you feel.
ArtvinAges 18 years+ - NCT07733869Recruiting
Core training for faster tennis serves
This trial tests if adding core muscle exercises to your routine can improve your serve speed. If you play tennis regularly and want to boost your game, this study may help you serve harder.
Beirut, BeirutAges 18–35 - NCT07734051Enrolling by invitation
Mobilization for kneecap pain
This trial tests if adding a groin-area mobilization to foot mobilization helps with kneecap (patellofemoral) pain. It may be for you if you have one-sided kneecap pain for at least 3 months, especially when climbing stairs, squatting, or sitting for long periods.
Fāqūs, SharkeyaAges 18–40 - NCT07736144Recruiting
Herbal formula study for fibromyalgia pain relief
This study tests a Chinese herbal formula called Yangyin Roujin (which nourishes yin and softens the muscles) to see if it helps reduce pain and other symptoms of fibromyalgia. If you have fibromyalgia and a pain level of 4 or more, you may be able to join.
Beijing, Beijing MunicipalityAges 18–75 - NCT07736456Enrolling by invitation
Exercise program for teens with mild to moderate scoliosis
This study tests a 16-week corrective exercise program for adolescents with idiopathic scoliosis. It aims to see if these exercises can improve spinal curves and posture without surgery or bracing.
Pristina, KosovoAges 10–18 - NCT07739082Recruiting
Virtual reality for teens with hunched back
This study tests if virtual reality exercises can improve posture in teens with a hunched back (thoracic hyperkyphosis). It may help by making therapy more engaging and effective.
CairoAges 13–18 - NCT07735195Recruiting
Grip strength test for healthy children
This study measures how strong children's grips are to create a reference range for what is typical. It may help doctors understand normal grip strength in kids.
Minneapolis, MinnesotaAges 2–12 - NCT07733518Recruiting
Exercise comparison for knee osteoarthritis
This trial compares two types of exercise—eccentric training and low-load blood flow restriction training—to see which is better for reducing pain and improving function in people with knee osteoarthritis.
Rawalpindi, Punjab ProvinceAges 40–70 - NCT07732803Recruiting
Robotic surgery results for bone injuries
This study looks at how well robots can help in surgery for broken bones and other orthopedic injuries. If you are an adult with a fracture and need surgery, you may be able to join.
Hong KongAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.