Rheumatology & orthopedics
Bones, joints & muscles clinical trials
Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We’re tracking 4,611 recruiting studies in this area right now.
By phase
- Not applicable3,768
- Phase 2217
- Phase 4200
- Phase 1182
- Phase 3139
- Phase 1/Phase 271
- Phase 2/Phase 334
Top conditions
- Knee Osteoarthritis172
- Rheumatoid Arthritis132
- Fibromyalgia105
- Osteoporosis82
- Osteoarthritis71
- Rheumatoid Arthritis (RA)68
- Osteoarthritis, Knee64
- Shoulder Pain48
- Hip Osteoarthritis43
- Psoriatic Arthritis40
- Degenerative Disc Disease39
- Chronic Pain38
- Total Knee Arthroplasty38
- Duchenne Muscular Dystrophy37
- Systemic Lupus Erythematosus37
- Musculoskeletal Pain35
- Osteoarthritis (OA) of the Knee32
- Pain32
Leading sponsors
- Riphah International University85
- Istituto Ortopedico Rizzoli69
- Cairo University65
- Assistance Publique - Hôpitaux de Paris36
- Foundation University Islamabad31
- Mayo Clinic28
- Massachusetts General Hospital25
- National Taiwan University Hospital25
- Hacettepe University23
- Tanta University22
Where studies are running
- California207
- New York87
- Florida82
- Maryland76
- Arizona72
- Massachusetts71
- Texas67
- Alabama59
- Illinois51
- Pennsylvania48
Recruiting studies4,611 total
- NCT07703332Recruiting
Stretching methods for arm pain from overuse
This study tests two different stretching techniques to see which one better relieves arm pain and improves movement in people with overuse injuries. It may help you if you have long-lasting discomfort from repetitive activities like typing or manual work.
Faisalabad, Punjab ProvinceAges 20–50 - NCT07699562Recruiting
EMG device study in healthy people and ICU patients
This study tests a device that records muscle activity (EMG) in healthy volunteers and critically ill patients in the ICU. It aims to learn how well the device works in different groups, which could help monitor muscle function in the future.
Evanston, IllinoisAges 18–90 - NCT07706244Recruiting
Does reducing pre-surgery anxiety help orthopedic patients recover better?
This study tests if a program to reduce anxiety before surgery (Enhanced Recovery After Surgery) improves how patients feel one year after major orthopedic surgery like knee, hip, or spine procedures, compared to standard care.
Hualien City, Hualien CountyAges 20–100 - NCT04116723Recruiting
Flexible brace treatment for teens with scoliosis
This trial tests whether a flexible brace can help improve or control adolescent idiopathic scoliosis in teenagers whose curve is in a specific range. You may be eligible if you already tried a rigid brace and meet other physical and safety requirements.
Hong KongAges 10–15 - NCT06648070Recruiting
Exercises for Upper Cross Syndrome in IT Workers
This study compares two types of physical therapy exercises to see which helps IT professionals with Upper Cross Syndrome (rounded shoulders and forward head posture) feel better. If you qualify, you'll get free treatment and help improve your posture and pain.
Rawalpindi, Punjab ProvinceAges 20–40 - NCT06533410Recruiting
Testing a new Chinese pain scale for fibromyalgia diagnosis
This study tests a new Chinese questionnaire to help doctors diagnose fibromyalgia more accurately. It is for people with long-lasting, widespread pain who can fill out a simple form.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06650046Recruiting
Topping-off technique for lower back arthritis
This trial tests a 'topping-off' surgical technique for people with arthritis and disc problems in the lower back. If you have tried 3 months of non-surgical treatments without success, this surgery may be an option to relieve pain and improve function.
Jinan, ShandongAges 18–85 - NCT06644729Recruiting
Shoulder surgery long-term study
This study looks at how patients who had rotator cuff repair surgery between 2010 and 2014 are doing now, including their shoulder function and x-ray results. It helps doctors understand long-term outcomes and when more surgery like reverse shoulder replacement may be needed.
OsloAges 18–95 - NCT06652061Recruiting
AI model to predict bone density from X-ray
This trial is testing an artificial intelligence (AI) model that uses X-ray images to predict bone density. If you have X-rays and a bone density scan, the AI may help doctors screen for osteoporosis without extra tests.
DhakaAges 18 years+ - NCT06653868Recruiting
Sticky bone grafts for front tooth implants
This trial tests two different types of sticky bone graft materials placed around a dental implant right after a tooth is removed. It aims to see which type helps the bone heal better around the implant in the front of your mouth.
CairoAges 20–50 - NCT06652724Recruiting
Psychological help for chronic pain in fibromyalgia and migraine
This study looks at how psychological factors and treatments might help with chronic pain in people with fibromyalgia and/or chronic migraine. It compares different groups to understand what works best.
Rome, RMAges 18–50 - NCT07692113Recruiting
Taping vs. movement control for big toe stiffness in athletes
This study compares two treatments for athletes with a stiff big toe (functional hallux limitus) that affects running. It tests whether a special tape or a movement retraining technique works better to improve toe motion and reduce pain.
Cairo, Zahraa AlmaadyAges 18–35 - NCT07696650Recruiting
Choose to Move Replacement Ready study
This study looks at a program called Choose to Move Replacement Ready (CTM-RR) for older adults and the people who help them get active. It tests how well the program works for activity coaches, participants, and healthcare referral partners.
Vancouver, British ColumbiaAges 50 years+ - NCT07689747Recruiting
Brain training and ankle tests for athletes with weak ankles
This study tests if adding a special computer-based brain training activity to regular ankle function tests can help teenage and young adult athletes who have ongoing ankle problems. If you are a licensed football, basketball, or volleyball player aged 16–25 with chronic ankle instability for at least a year, you may be eligible.
Istanbul, SarıyerAges 16–25 - NCT07694882Recruiting
Gentle pressure techniques for chronic neck pain
This study tests two different types of gentle pressure techniques (myofascial release) to see which one helps relieve long-term neck pain and improve everyday function. It is for people with chronic neck pain that isn't caused by a specific injury or disease.
Famagusta, HatayAges 18–45 - NCT07693634Recruiting
Online rehab for knee pain in active adults
This study tests a home-based tele-rehabilitation program for people with front knee pain (patellofemoral pain syndrome) who are recreational athletes. It aims to see if online guided exercises can reduce pain and improve function.
Faisalābad, PunjanAges 18–35 - NCT07689045Recruiting
Comparing two nerve blocks for shoulder surgery pain
This trial compares two types of nerve blocks for pain control during and after Bankart or Latarjet shoulder surgery. The goal is to see which block provides better pain relief and preserves arm strength.
Cairo, Cairo GovernorateAges 18–65 - NCT07690514Recruiting
Ultrasound treatment for cervical dystonia
This study tests a new type of ultrasound treatment for cervical dystonia (neck muscle spasms). It uses focused sound waves to target the brain areas causing the condition, and aims to see if it can reduce symptoms without surgery.
Toronto, OntarioAges 18–90 - NCT07688915Recruiting
High-intensity laser vs. steroid injection for chronic back and leg pain from a herniated disc
This study compares two treatments for long-lasting low back and leg pain caused by a herniated disc: high-intensity laser therapy and a steroid shot near the spine. Researchers want to see which option works better to reduce pain.
AnkaraAges 18–65 - NCT07692126Recruiting
Neck pain and hand strength: core vs shoulder exercises
This study compares two types of exercises to see which better improves hand grip strength and neck pain. If you have had chronic myofascial neck pain (trigger points) in the upper shoulder muscle for over 6 months, this trial may help find which exercise works best for you.
Giza, Giza GovernorateAges 25–45 - NCT07692061Enrolling by invitation
Speech therapy study for Cantonese-speaking kids with cleft palate
This study tests a new speech therapy program for children and teens (ages 4–17) who had cleft palate repair before age 2 and have certain speech sound errors. It aims to improve their speech clarity and communication.
Shatin, New TerritoriesAges 4–17 - NCT07695883RecruitingPhase 3
Vitamins and minerals for teen girls' health
This study tests whether giving teen girls extra vitamins and minerals improves their growth and health. It may help girls who are still growing and living at home.
Rangpur CityAges 10–18 - NCT07694999Recruiting
Ice packs vs cold baths for heel pain relief
This study compares using ice packs or cold baths along with standard exercises to treat plantar fasciitis, a common cause of heel pain. It aims to see which method works better for reducing pain and improving function.
Peshawar, Khyber PakhtunkhwaAges 18–65 - NCT07688863Enrolling by invitation
Comparing breathing muscle training methods for heart failure
This trial compares two different types of breathing muscle training to see which works better for people with heart failure and weak breathing muscles. You may join if you have heart failure with reduced pumping ability and are stable overall.
Viña del Mar, ValparaisoAges 18 years+
Common questions
- How many bones, joints & muscles clinical trials are recruiting?
- Clin2 is tracking 4,611 recruiting rheumatology & orthopedics studies from the U.S. registry right now, out of 7,492 we cover in this area in total.
- What does “Bones, joints & muscles” cover here?
- Arthritis, osteoporosis, and other conditions of the bones, joints, and muscles. We group each study into bones, joints & muscles based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a bones, joints & muscles trial near me?
- Use the search to filter bones, joints & muscles studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.